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Doctor insights on: Lip Biopsy Side Effects

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What does a lip biopsy diagnose? Only sjorgens?

What does a lip biopsy diagnose? Only sjorgens?

Usually: Sjorgens is commonly DX with a lip bx, but if you have a lesion on your lip or some other abnormality of unknown cause, a bx of that area may also be warranted. ...Read more

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Dr. Debra Rosenblatt
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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How much does a lip biopsy hurt?

How much does a lip biopsy hurt?

Painful: Necessary esp if smokes, heals fast but will be painful but can be numbed well. ...Read more

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Lip biopsy for sjorgrens - is it really needed, or are blood tests enough?

Sjogren's : Sjogren's is diagnosed based on symptoms, good clinical exam , laboratory data and anti body levels. At times imaging studies are done to evaluate salivary glands, eye exam for dryness , chest x-ray for lung involvement and kidney tests for kidney involvement . At times lip biopsy to confirm diagnosis. ...Read more

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Lip biopsy- seronegative sjogren's. What's diff in + & -? See dr 11/25. Any suggestions or where to find info? Very sick year. Had 2 ivig's for my ms

Lip biopsy- seronegative sjogren's. What's diff in + & -?  See dr 11/25. Any suggestions or where to find info? Very sick year. Had 2 ivig's for my ms

Complex: I gather you have MS diagnosed, associated with Sjogren's if lip biopsy was positive, but am confused as to why you ever had IVIG, which is ineffective in most MS situations. There are 13 disease modifying agents, and if you have MS, you should be on one of these. Seek info form MS Society, American Academy of Neurology, and Sjogren's Association. ...Read more

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Dx w/ undifferentiated connective tissue disease 9/11/13. Where & how do I find any good info. Lip biopsy may prove sjorgrens. Relieved i'm not crazy.

Auto immune diseases: These are diseases of immune system that involves joints , cartilage, muscles and skin in multiple organs including eyes, heart, lungs, kidneys, GI tract, blood vessels, nervous system and bone marrow to name few and include lupus, vasculitis , sjogrens etc . Some patients do not fulfill the criteria established for any disease and are called undifferentiated connective tissue disease.Fu with rheumato. ...Read more

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ENT says salivary lip biopsy only 40% accurate to Dx Sjogrens, and suggests parotid gland biopsy, saying 80 accurate%. Is this correct?

ENT says salivary lip biopsy only 40% accurate to Dx Sjogrens, and suggests parotid gland biopsy, saying 80 accurate%.  Is this correct?

Sjogren's: I've not seen those exact percentages noted in the medical literature, but they may certainly be reasonable. The key to diagnosis of this disorder is the salivary gland cells. The best place to perform biopsies to get salivary cells are in the lower lip and the tail of parotid. A lip biopsy can be done without a visible scar. A tail of parotid biopsy will scar, but you can usually hide it well ...Read more

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Can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? My rheumatologist says yes so only a lip biopsy will show sjogrens. Have all symptoms.

Can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? My rheumatologist says yes so only a lip biopsy will show sjogrens. Have all symptoms.

Sometimes: Remember, a lip biopsy is not always a definitive test. If the biopsy specimen does not contain salivary glands, then the diagnosis cannot be confirmed. Rather than a lip biopsy, why not just treat the symptoms? ...Read more

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Dx sjogrens 11/2/13. diangosis MS 3/05/2001. Ms ? Thens?Tap showed +. 1 doc thought nom labs -. Sjogrens labs - lip biopsy was + 24 out of 4. I am in wheelchair. No reflexes in lower limbs. Is nom possible

Dx sjogrens 11/2/13.  diangosis MS 3/05/2001. Ms ? Thens?Tap showed +. 1 doc thought nom labs -. Sjogrens labs - lip biopsy  was + 24 out of 4. I am in wheelchair. No reflexes in lower limbs. Is nom possible

Do you mean NMO?: This is complex. Gather you do have sjogren's, and seems that you must have some spinal cord issues, but do you really have multiple sclerosis or neuromyelitis optica? An anti-aquaporin 4 test can help, and would just to be safe, recheck ss-a and ss-b, but also get b-12, methylmelonic acid, homocysteine, updated spinal cord mri. Suggest you get evaluated at mayo clinic. ...Read more

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Why do u think my md still suspects sjogrens vs lupus(ana 1:640, negative lip biopsy, raynauds, fatigue, photosens, rashes, jt/muscle pain, sicca ?

Why do u think my  md still suspects sjogrens vs lupus(ana 1:640, negative lip biopsy, raynauds, fatigue, photosens, rashes, jt/muscle pain, sicca ?

Undifferentiated CTD: Clinical presenation can be classified as an undifferentiated connective tissue disease (uctd). Likely not primary sjogren's since lip biopsy (usually gold standard for diagnosis of sjogren's) was negative. Would recommend additional evaluation including specific antibodies such as dsdna and ena. Also would recommend rheumatology consult. ...Read more

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What are the side effects of a parathyroid biopsy?

None: Unclear how this biopsy was done. If it was needle biopsy there should be no side effects. If during surgery unlikely to cause problems. ...Read more

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