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Doctor insights on: Linzess Is For Long Term Use

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Is amitiza (lubiprostone) or linzess safer for long term use for ibs? 18 year old male with Wolff-Parkinson-White syndrome.

Is amitiza (lubiprostone) or linzess safer for long term use for ibs? 18 year old male with Wolff-Parkinson-White syndrome.

Ok: Neither are contraindicated for WPW but Amitiza (lubiprostone) has no black box warnings and Linzess does - since clinical experience with both is limited, i'd go with the former. ...Read more

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I use oxymorphone ER for pain. I have constipation tried oc's & linzess, amitiza, relistor (methylnaltrexone). I use enema evry 3 days. Is this safe 4 long term usage?

I use oxymorphone ER for pain. I have constipation tried oc's & linzess, amitiza, relistor (methylnaltrexone). I use enema evry 3 days. Is this safe 4 long term usage?

Constipation: You don't say why you're using the narcotic or how much time or how much. Constipation is a serious problem over a long time. Using laxatives or any thing of the sort can can lead to dependence on those medications. You end up in later years being very miserable. Of course if you're legitimately taking opiates constipation is a side effect. Minimize the problem. ...Read more

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How long has the drug "linzess" been in the market?

How long has the drug "linzess" been in the market?

Few months: Only out for several months but seems to be very effective for irritable bowel with constipation as primary symptom. Tested for a long time as per fda prior to its release. ...Read more

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I was taking linzess and it worked great, but, insurance will no longer cover the cost and it is expensive. Is there a cheaper med that works similar?

I was taking linzess and it worked great, but, insurance will no longer cover the cost and it is expensive. Is there a cheaper med that works similar?

Amitiza (lubiprostone): An equivalent medication would be amitiza (lubiprostone). Check with your doctor to see if it is right for you and if your insurance will cover it. Alternatively your doctor can ask for special authorization for you for linzess. ...Read more

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Was the IBS drug linzess tested long enough to be considered safe?

Was the IBS drug linzess tested long enough to be considered safe?

FDA approved...: Getting drugs approved for use in the us is far more stringent than in other countries. The data on Linzess demonstrates a very favorable side effect profile. Like with any new drug, long term safety remains largely unknown. Good luck! ...Read more

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I have IBS-C w/ severe, chronic constipation. Started Linzess (145mcg) 2 days ago, but no difference in symptoms yet. How long does it take to work?

I have IBS-C w/ severe, chronic constipation. Started Linzess (145mcg) 2 days ago, but no difference in symptoms yet. How long does it take to work?

You must: Measure in terms of WEEKS not DAYS since you should be following a dietary intake consistent with your IBS type! Consult with your Gastroenterologist about what you should be eating. One thing I can advise...DRINK LOTS OF FLUIDS!!!!!!!!!! and start NOW!

Good luck
Hope this helps!
Dr Z ...Read more

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I just started taking linzess, the highest dose. How long will it take for it to start working and my bowel movements to become regular?

I just started taking linzess, the highest dose. How long will it take for it to start working and my bowel movements to become regular?

Great drug choice: Linzess is a non-systemic agent that works within 1 week to improve both the frequency and completeness of emptying, and within 6-8 weeks to reduce the sense of abdominal discomfort that often accompanies constipation. Take one pill before your first meal daily. ...Read more

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Hw long does pantoprazol 40mg take 2work. On day 3.still have bitter taste n some acid. Can I tke simethicone 80mg to help w. Gas. Start linzess today.

Hw long does pantoprazol 40mg take 2work. On day 3.still have bitter taste n some acid. Can I tke simethicone 80mg to help w. Gas. Start linzess today.

Protonix (pantoprazole): Protonix (pantoprazole) starts to work fairly quickly - although takes 2-3 days to reach maximal effect (ie, you should have noticed some improvement by now). Remember to take any PPI at least 1 hour before or 2 hours after eating - as food decreases absorption by up to 70%. Linzess should help with any constipation. Hope that helps! ...Read more

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What number of linzess 145 mcg capsules do I take?

Start with one: The starting dose is one tablet, but there is also a dose of 290, (which obviously is equal to two of the 145 mg tabs). Either dose can be effective, depending on the patient ...Read more

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Linzess linaclotide 290mcg capsule treats what disorder

Linzess linaclotide 290mcg capsule treats what disorder

Linzess (linaclotide: Was approved by fda at end of august 2012 to treat chronic idiopathic (= cause unknown) constipation & irritable bowel syndrome with constipation it's approved is for adult patients only. Increases cgmp in intestine, which stimulates secretion of chloride & bicarbonate (sodium bicarbonate) resulting in increased intestinal fluid & accelerated transit. ...Read more

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What will happen if you take more than one linzess a day?

What will happen if you take more than one linzess a day?

Maximum dose 290 mcg: Read more re: safety questions at: https://www. Accessdata.fda.gov/drugsatfda_docs/nda/2012/202811Orig1s000MedR. Pdf ...Read more

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I took two linzess 290 mcg one at 11 and one at 11:57 I'm not 100% sure I took it will I be okay?

I took two linzess 290 mcg one at 11 and one at 11:57 I'm not 100% sure I took it will I be okay?

Potential overdose: Check out http://www. Drugs. Com/linzess. Html. "What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide." ...Read more

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What's the difference between linzess and amatiza?

What's the difference between linzess and amatiza?

Constipation Rxs: Both medicines are used for treatment of constipation. The mechanism of action of the two medicines are different. Linzess usually works faster. ...Read more

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What are the side effects of linzess?

What are the side effects of linzess?

Linzess side effects: You should stop using Linzess and call your doctor immediately if you have a serious side effect such as severe or ongoing diarrhea, black, bloody, or tarry stools. Or severe stomach pain. Other common Linzess side effects may include mild diarrhea, heartburn, vomiting, gas, bloating, mild stomach discomfort; cold symptoms and headache. ...Read more

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Why did the medication "Linzess" kill juvenile mice in the clinical studies? Should this be a concerning result?

Why did the medication "Linzess" kill juvenile mice in the clinical studies? Should this be a concerning result?

Let's think: Mouse studies are animal studies, not clinical studies. It is no surprise that an anti-constipation drug in a huge dose caused fatal diarrhea. Two new Big Pharma meds are competing for the chronic constipation market and it's no wonder there's distortion in what you read. For constipation, check for hypothyroidism, porphyria, and practice good hydration and diet first. Best wishes. ...Read more

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On linzess for about 3 weeks. Hasn't worked. If anything made me feel worse. Could there be more wrong. With me? Maybe a blockage?

On linzess for about 3 weeks. Hasn't worked. If anything made me feel worse. Could there be more wrong. With me? Maybe a blockage?

Great drug choice: Linzess is a non-systemic agent that works within 1 week to improve both the frequency and completeness of emptying, and within 6-8 weeks to reduce the sense of abdominal discomfort that often accompanies constipation. If you've taken one pill before your first meal daily without benefit, consider either a dose adjustment or proceed with further evaluation. ...Read more

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Can I take probiotics with linzess?

Can I take probiotics with linzess?

Yes: Hi, yes u can. There is no real interaction that we know of. Having said that a few normal pts who have tried probiotics describe diarrhea probably as a consequence of the change in the flora of the intestine. So monitor for the same and discuss with the physician who prescribed the linzess. Hope this helps. ...Read more

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Could I take probiotics while on linzess?

Could I take probiotics while on linzess?

Yes: Linzess is used to treat the constipation associated with ibs. Most common reported adverse reaction with Linzess is diarrhea. There is no specific contraindication to taking probiotics and best to monitor consistency of bowel movements. ...Read more

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Which is better for gastroparesis amitiza (lubiprostone) or linzess?

Which is better for gastroparesis amitiza (lubiprostone) or linzess?

Gastroparesis: Have you already been diagnosed with gastroparesis? Documentation of delayed emptying of gastric contents is required before treatment. All patients with symptoms of gastroparesis which include nausea, vomiting, early satiety &fullness/bloating need to be screened for diabetes mellitus, hypothyroidism, neurological disease, autoimmune disease, past surgery. Please see your MD for a full exam. ...Read more

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Can u take lactlouse and linzess and prilosec all at the same time?

Can u take lactlouse and linzess and prilosec all at the same time?

Separate or together: Your question is best answered by prescribing doctor who may not agree w/unknown anonymous online guy. There's potential minor interaction btwn Linzess & other 2 drugs (http://www. Drugs. Com/interactions-check. Php? Drug_list=1427-0, 3413-15864, 1750-1118). 1st 2 are for constipation while 3rd is for heartburn. I don't see any issue w/taking together except that Linzess is to be taken 30min b4 breakfas ...Read more

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I've taken Nexium (esomeprazole) this morning can I take linzess this afternoon

I've taken Nexium (esomeprazole) this morning can I take linzess this afternoon

Probably fine: Linzess (linaclotide) is usually taken on an empty stomach, about 30 minutes before breakfast. If taken soon after a high-fat meal, it can cause diarrhea or more frequent movements. I would avoid taking both Nexium (esomeprazole) and Linzess on the same day if Nexium (esomeprazole) has ever caused you to have diarrhea (a possible side effect). ...Read more