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Life Expectancy Prostate Cancer Bone Metastases
Can be years: These patients can survive years, depending on if they don't have other organ involvement also if they are responsive to hormone treatment. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
What does the pain from bone metastases feel like what other symptoms are there and any specific to metastases from breast cancer?
My aunt is recently diagnosed with secondary bone metastases from breast cancer, which sounds really bad?
Treatable, incurable: I am sorry for your aunt. When the cancer has spread to other area beyond the primary organ-i.e.Breast- it is called stage iv. It is incurable, however treatable and there are many treatment options available-which will depend on the er/pr and her2neu status of the cancer. Bisphosphonates such as zometa or xgeva (denosumab) are available to decrease risk for fracture. Radiation tx is available to reduce pain. ...Read more
What can we expect from a stage 4 lung cancer patient with bone metastases- what can be done in case all treatments are ruled out?
Hospice: Palliative of pain and comfort care only. ...Read more
Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more
Can you explain if it's possible that someone is expected to live for 3 months with prostate cancer with bone marrow metastasis?
For treatment of bone metastasis associated with prostate cancer, is xgeva (denosumab) a better one compared to zometa? How much does xgeva (denosumab) cost?
Xgeva (denosumab): Zolmera can have more side effects, that is my view. ...Read more
Dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. What kind of hormone therapy shall he use?
Surgical vs medical:
There are 2 ways to address this.
Surgical castration with bilateral orchiectomy is a good option with a one time surgery and good relief.
Medical castration ie combined androgen blockade is done with Casodex and Lupron (leuprolide) (expensive and need to be given at periodic intervals. Talk to your oncologist and see how your father wishes to proceed. Palliative radiation is a good option for bone pain. ...Read more
What do you suggest if my grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones,?
No major interventions.
Kindness. Caring, listening, loving!
Dad has advanced prostate cancer with bone metastasis. After orchirectomy, psa down from 270 to 10. Shall he start zometa or xgeva (denosumab)? Which is better?
Bones: Xgeva (denosumab) has less side effect profile in my opinion. ...Read more
My grandfather 94yrs old having prostate cancer and also has metastasis in pancrease (pancrelipase) and bones. Treatment options?
No treatment: In spite of your grandfathers clinical condition, the pattern of behavior of prostate cancer after 80, for the most part typified by an indolent form of metastasis. One uses drugs like Lupron (leuprolide) to reduce hormones but at his age there are probably little or no hormones secreted. Chemo such as Taxol not utilized. Therefore he should live normal expected time for a 90yo without further intervention ...Read more
My dad is 68 years old. Recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. What kind of hormone therapy shall he use? Is orchiectomy ok?
Orchiectomy OK but: The standard of care is an lhrh agonist (such as lupron, zoladex) injection combined with a drug taken by mouth called casodex. The Casodex should be used for a minimum of 1 month and then can be stopped. The advantage is that these injections can be as little as once every 6 months. Alternatively, a drug called Firmagon (degarelix) (an lhrh antagonist) can be given monthly without the casodex. ...Read more
Advanced Cancer: Once prostate cancer has spread to the bones, the prognosis becomes poorer. Treatment revolves around suppressing growth by decreasing testosterone. This hormone deprivation, however, only helps for a little while. Eventually the disease will progress. Other treatments are possible, but all in all only 1/3 men in this situation survive 5 years. ...Read more
What is the life expectancy for a 65 year old with metastic prostate cancer in the bones lungs and liver. The doctors have stopped all cancer treatmen?
Radical Remission: Is the name of a book by Kelly Turner. She investigated the cases of people who had dire prognoses and yet lived long beyond them. It might be worth a read for the situation you mention. Peace and good health. ...Read more
It depends: There are 2 factors that are important. One is the type of cancer and the second is the response to treatment. For metastatic breast or prostate cancer to bone that responds to hormone treatment it could be years. For melanoma that is not responsive it could be a few months. ...Read more
Looking for....: Any abnormalities of the bone. Most specialists are very used to seeing "normal" bone - this makes us very keen on seeing anything that is not normal. Sometimes metastases are obvious and sometimes very subtle. ...Read more
Usually: Bone metastases are where cancer from one site (breast, prostate, lung) spreads through the blood and begins to grow in the bone. This can have a characteristic appearance on scans. The way to prove it is cancer is to take a biopsy. However, if cancer has already been diagnosed, bone metastases can be diagnosed by a characteristic bone scan or other radiographic test. ...Read more
For bone metastases what are the benefits and costs of local infiltration of anesthetic over palliative radiation?
Talk to an expert: Radiation oncologists are experts in the treatment of bone metastases by radiation, and are the best doctors to answer this question for you. If pain is the chief problem, consult a pain specialist. Local infiltration with an anesthetic such as Lidocaine will provide only brief, temporary pain relief and is not a solution. The kind of cancer is important to know before treatment. ...Read more
Not great: X-RAYs are relatively insensitive in the detection of early or small metastatic lesions. Although CT scans are superior, CT scanning is relatively insensitive in showing small lesions, and it has the disadvantage of limited skeletal coverage. Bone scans are very sensitive (they'll pick up everything) but nonspecific (could be just arthritis). MRI and PET scanning are accurate but very expensive. ...Read more
The prostate is a gland that lies at the base of the bladder and surrounding a segment of urethra. It secretes a milky fluid that is discharged by excretory ducts into the urethra during the emission of semen. It is clinically important because enlargement of the prostate with age, and prostate cancer are two common ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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