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Doctor insights on: Life After Stem Cell Transplant

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Life expectancy of myeloma patients after autologous stem cell transplant?

Life expectancy of myeloma patients after autologous stem cell transplant?

Myeloma : There are many things that go into predicting life expectancy of somebody with myeloma who has an autologous stem cell transplant. The rough estimate for somebody getting a transplant in first remission is about 6-7 years now. However, this is something your oncologist or transplant doctor can talk to you about with more specific information. ...Read more

Dr. Keith Stockerl-Goldstein
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Stem Cell Transplantation (Definition)

A stem cell transplant may be needed if you have a disease that damages the cells in the bone marrow or if your received high doses of chemotherapy or radiation. Depending on the type of transplant, your procedure may be called a bone marrow transplant, a cord blood transplant, or a peripheral blood stem cell transplant. All three use stem cells, which are immature cells that give rise to specific cell types. Stem cell transplants are similar to blood transfusions and generally ...Read more


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What are the survival rates for cll cancer after donor stem cell transplant?

What are the survival rates for cll cancer after donor stem cell transplant?

Select patients: Allogeneic (donor) stem cell transplants can be conducted using less intensive (non-ablative) regimens with excellent results for patients with CLL. It is not the first line of therapy, since patients can have remissions of several years with simpler therapies. Fatal complications still may occur in 25% of patients, but unlike other treatments, the remainder have a good chance of being cured. ...Read more

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What's involved in allogeneic stem cell transplantation?

What's involved in allogeneic stem cell transplantation?

Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease. ...Read more

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For leukemia has anyone had a successful stem cell transplant?

For leukemia has anyone had a successful stem cell transplant?

Many: There are different types of leukemia, lymphoid vs myeloid, acute vs chronic. Some leukemia can be treated for chemotherapy only, some leukemia will need to be treated by stem cell transplant. The outcome of stem cell transplant is different depending on what type of leukemia a patient has. However, stem cell transplant has an established record to cure leukemia. ...Read more

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Stem cell transplant for ovarian cancer--will it prolong survival rate?

Stem cell transplant for ovarian cancer--will it prolong survival rate?

Yes possible: With out knowing stage and cell type of ovarian cancer , in general high dose chemotherapy with autologous ( patients own ) stem cell transplantation is promising to prolong the life, cure is not near yet, as most of the tumors are drug resistant ( or right drug is not there ) and have residual tumor in the body. ...Read more

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How risky are stem cell transplants?

How risky are stem cell transplants?

Stem Cells: Stem cell injections are now being used to treat painful joints (shoulders, hips, etc), Alzheimers, ALS, Lyme, Cerebral Palsy, etc. Still there are not great published studies proving its benefit in many of these conditions. We have been using limbal stem cell transplants in eye surgery for years with excellent results. See [email protected]: depends on where the stem cell is from & for. ...Read more

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Has anyone had a successful stem cell transplant for cancer?

Has anyone had a successful stem cell transplant for cancer?

For certain diseases: Stem cell transplants (bone marrow transplants) are often successful at treating cancers of the blood and bone marrow such as leukemias, lymphomas and multiple myeloma. They can also be used to treat some disorders of the red blood cells and immune system. ...Read more

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Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

Dr. Al Hegab Dr. Hegab
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Refractory ALL in adolescent male 21 years management other than Allogeneic Stem Cell Transplant?

Dr. Al Hegab Dr. Hegab
4 doctors agreed:
Refractory ALL in adolescent male 21 years management other than Allogeneic Stem Cell Transplant?

Complex question: only experts in the field, hematologists/oncologists would answer this question after careful review of the case and different options available, I know it might be frustrating at times, but complex condition as ALL need to be managed in specialized hospitals/institutions, it's your right as a patient to have second and even third opinion, but in the end you have to trust the treating team, good luck ...Read more

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When is a stem cell transplant used nowadays?

Several diseases: Including acute leukemia, multiple myeloma, some forms of resistant lymphoma, aplastic anemia and a few other rare disorders. ...Read more

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Is a bone marrow transplant life threatening?

Is a bone marrow transplant life threatening?

There are risks: There is a risk of dying of a complication of a bone marrow transplant. The risk is dependent on whether the cells are your own or from a donor. Also, the degree of matching impacts the risk. The major life threatening complications are related to infections, organ failure and an immune system problem called graft-versus-host disease. ...Read more

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Is it reasonable to have second autologous stem cell transplant for myeloma?

Yes: This is a very difficult question today because every situation with myeloma is different. We do not double transplant all myeloma patients like we have done in the past. It is sometimes reasonable if the first was previously successful and donor cells remain. We now have so many treatments for myeloma that sometimes we do an allogeneic transplant or treat with other drugs (velcade, carfilzomab. ...Read more

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Does getting radiation, chemotherapy, and a stem cell transplant affect chances of having kids later in life?

Yes: I am not sure of your gender, but for women, usually this leads to cessation of ovulation, that may recover later. For men, sperm count may be significantly reduced, and depending on what chemo agent used, this may be permanent. ...Read more

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Can stem cells cure a blind patient who has a failed corneal transplant before?

Possibly: If the patient has a corneal limbal stem cell deficiency then a transplant may be beneficial. Ask your corneal surgeon. ...Read more

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What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

Multiple sclerosis : Researchers are optimistic. Yet, no proven efficacy as of yet. Mortality is down to 1-2%. Check following site: http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/18565456/. ...Read more

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160 days Post auto stem cell transplant for NHL double hit cell counts low hemoglobin 9.6 platelets 63 white cells 1.7. Can this resolve on its own in time? How long? Fearing MDS.

Several possibilitie: There are several possibilities, but this may simply be a slow recovery after engraftment, especially if the trend is one of gradual improvement. You should be checked for vitamin B12 and folate (folic acid) deficiency. If the low counts are progressing, then discuss with your transplant physician a bone marrow with cytogenetics to rule out MDS, although MDS usually occurs at a longer interval after SCT. ...Read more

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Does stem cell transplantation treat hematologic cancer?

Does stem cell transplantation treat hematologic cancer?

Yes: Stem cell transplant is used to treat leukemias and lymphomas, both are types of hematologist malignancies. ...Read more

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What's the life expectancy after a double lung transplant?

What's the life expectancy after a double lung transplant?

Multiple factors: It is a complex question, since survival varies depending on a number of factors, including infection and rejection episodes. One year survival is usually 90% at most centers. ...Read more

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Can stem cell transplants cure multiple myeloma?

Remission: Multiple myeloma is treated classically with chemotherapy and autologous stem cell transplantation. Both modalities can put the disease on remission and prolong life substantially. I personally do not offer allogeneic stem cell transplant for multiple myeloma unless on clinical trial or under very stringent circumstances. Multiple myeloma remains an incurable but very treatable disease. ...Read more

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Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


Dr. Sewa Legha
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Stem Cell (Definition)

The capacity to "grow up" or differentiate to produce mature cellular elements. In blood production rbc, WBC and platelets. Fundamentally, stem cells can also self-replicate and thus provide a pool of ...Read more