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Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
What is the life expectancy of a person with chronic lgl leukemia that is under control but not in remission?
Are there other need as effective for treating lgl leukemia as methotrexate that aren't as hard on kidneys.
Obesrvation or Tx: Large granular lymphocyte (lgl) leukemia (t-cell or nk-cell) may be observed until there are symptoms due to -- anemia (low hgb), neutropenia (low wbc, anc), thrombocytopenia (low platelets). Treatment may be with methotrexate, cyclosporine, cyclophosphamide, steroids. These drugs all may have associated side effects and should be monitored. ...Read moreSee 1 more doctor answer
Yes: This is a malignancy arising from the white cell forming elements of the bone marrow. It crowds out the red cells and platlets leading to anemia, bleeding tendency and since the white cells produced are ineffective, infection is common. This is lethal unless treated and modern treatment can be very effective. Your friend probably is in the right track if the diagnosis has been made. ...Read moreSee 1 more doctor answer
Many things: These can increase your risk, but do not mean you will get leukemia: 1. Family history of leukemia 2. Exposure to certain chemicals, eg benzene (found in degreasers) 3. Exposure to high or chronic radiation eg nuclear reactors 4. Previous chemotherapy or radiation therapy 5. Myelodysplastic syndrome 6. Downs syndrome and other genetic diseases 7. Smoking! ...Read moreSee 2 more doctor answers
Blood or bone marrow: Typically this s diagnosed by a bone marrow test. In the marrow will be the abnormal proliferation of cells of the same type. At times, these cells in the can "spill" into the blood. When this occurs, the leukemia s diagnosed on blood tests. Even when noticed in the blood, a marrow test is usually performed as well. ...Read moreSee 1 more doctor answer
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