Doctor insights on:
Levophed Norepinephrine Dopamine
Receptors: These three medications are used to support the heart and cardiovascular system ie. blood pressure and heart rate. They are known as sympathomimetics and have a similar response to what you would think of as adrenaline. Each has variable effect on either heart rate, heart function (in terms of strength of 'squeeze') and on blood vessels which would translate to higher blood pressure. ...Read more
I was wondering what are the differences of levophed, (norepinephrine) dopamine and dobutamine in terms of their action?
You Asked for It----:
Dobutamine- direct b1 receptor stimulant or agonist in the sympathetic nervous system.
Levophed- vasoconstrictor peripherally (alpha adrenergic effects) and beta adrenergic stimulant at the level of the heart and coronary vessels
dopamine- dual b1 and Alpha adrenergic effects. Useful in hypovolemic shock because of conservancy of renal blood flow. Also, works centrally in other complex ways. ...Read more
Catecholamines: Behavior is much more complex than neurotransmitter levels alone. But norepinephrine (ne) acts mainly in an area of your brainstem called the locus coeruleus. When released, ne triggers the stress response. Ne is also involved in pain, cognition, mood, emotions, movement and blood pressure. Dopamine is involved in regulating mood, pleasure, delusions, psychosis and drug abuse -- and more. ...Read more
Catecholamines: These are both catecholamines, synthesized from the Amino Acid tyrosine. Norepinephrine (ne) acts mainly in an area of your brainstem called the locus coeruleus -- triggering the stress response. Ne is also involved in pain, cognition, mood, emotions, movement and blood pressure. Dopamine is involved in regulating mood, pleasure, delusions, psychosis and drug abuse -- and more. ...Read more
Wellbutrin (bupropion): Wellbutrin (bupropion) acts by enhancing the levels of serotonin, dopamine, and norepinephrine at the site of each neurotransmitter. For this reason, it's an excellent medication choice for depression and executive functioning, such as conditions with attention and concentration impairments. However, due to its actions upon dopamine, it is relatively contraindicated in psychotic conditions. ...Read more
St Johns wort: Is a very potent herb and should not be used with other anti-depressants. ...Read more
Yes, since: Acetylcholine is the preganglionic transmitterGet a more detailed answer ›
Motivation: Actually, the 3 working in harmony.Get a more detailed answer ›
Sine seratonin depletes other nerotransmitters like dopamine, norepinephrine, and epinephrine...By "deplete" does it mean a permanent thing?
Not correct: Serotonin does not deplete other neurotransmitters, but there is a balance especially between Dopamine and serotonin. This balance is dynamic and constantly re-establishing itself. Unless there is damage to neurons (which there can be when abusing certain drugs) neurotransmitter changes would not be permanent. ...Read more
What p450 enzymes are inhibited/induced by seroquel, (quetiapine) and what does a dopamine/norepinephrine antagonist do? Reduce dopamine levels? Specifics please?
Neither: Seroquel (quetiapine) passes through the cyp450 3a4 pathway & is extensively metabolized, but it neither inhibits nor induces the pathway itself. On the other hand, it's metabolism may be significantly affected by other medications. For instance, Dilantin induces the pathway causing seroquel (quetiapine) to be rushed through the pathway, leading to less-effective, lower blood levels. Antagonists are blockers. ...Read more
14/male results/ catecholamine norm? Norepinephrine, supine 136.0 pg/ml * epinephrine, <10 pg/ml *dopamine, <10 pg/ml norepinephrine, stand 457.0 pg/ml epinephrine, 14.0 pg/ml dopamine, 16.0 pg/m
Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?
Go after it!: Kenneth, that's a great question. I encourage you to get a Ph. D. in neurobiology and devote your career to finding out the answer, because if you do, you will win about three Nobel Prizes in Medicine. In fact, you'll win if you can find an effective way to measure neurotransmitters in the living brain all at once for more than a minute at a stretch AT ALL, let alone for Tourette's. ...Read more
How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor, without affecting dopamine?
Strattera (atomoxetine) blocks: Reuptake of norepinephrine but rat studies show that it also raises levels of Dopamine in the prefrontal cortex 3x without raising levels in the nucleus accumbens that controls addiction and where the other stimulant drugs also act. Dr. Stephen stahl calls some of the cells in the prefrontal cortex promiscuous because they contain both norepinephrine and dopamine. There is more to be learned. ...Read more
Can Xanax (alprazolam) cause brain fog? Also can low norepinephrine cause brain fog? I feel as if my dopamine is fine anything besides stims help with "fog"?
"Low"? "Normal"?: You're treating the human brain like a casserole. You're reducing to absurd simplicity an organ whose complexity surpasses human understanding. Neurotransmitters SO don't work that way. There is no "low" or "normal" the way you' think of it. Neurochemistry isn't a New Age fad. Your awareness of it is commendable but you labor under major misconceptions. You can learn more. It's not beyond you. ...Read more
I have been prescribed Vyvanse and Adderal to treat my ADHD for the past six years. I am concerned that my dopamine & norepinephrine levels will not be restored when I get off my Rx. Should I be worried about permanent collateral damage to my brain?
You are already worried and it is imperative that you discuss this with the doctor who is controlling your medicines.
I would appreciate learning what your doctor (s) have told you. ...Read more
Does ibuprofen raise or lower levels of serotonin dopamine or norepinephrine in the brain? Or something else?
There are no levels: There are no "levels" of neurotransmitters (NTs) in the brain. They don't just float around freely as if in blood. NTs are constantly being dynamically synthesized in neurons, being released into synaptic clefts, & within milliseconds undergoing reuptake either before or after the molecules have been destroyed & recycled into making more NTs. Furthermore, NTs differ depending on the brain region. ...Read more
See below: Levophed’s dosing is variable, depends on the condition treated, and may itself change depending the reference or guideline you consult). A common treatment is for low blood pressure/shock, 0.1-0.5 mcg/kg/minute, adjusted to desired pressure response. An older approach some still use is flat dosing (without regard to patient weight) of 8-12mcg/minute to start and a maintenance dose of 2-4mcg/min. ...Read more
Is levophed (norepinephrine) being used more now as a first choice of treatment for head injuries?
Levophed (norepinephrine): Norepinephrine is not specifically used for treatment of head injuries per se but it is used routinely in ICU settings for maintaining blood pressure in critically ill pt's such as those suffering from acute neurologic trauma to attempt to maintain cerebral perfusion in the face of elevated intracranial pressure. ...Read more
Atomoxetine inhibits serotonin transporter, dopamine transporter and naroephinephrine. What does inhibit mean?
Strattera (atomoxetine): Inhibition is the opposite of stimulation, so the effectiveness is reduced. ...Read more
What are the best foods to increase dopamine and norephinephrine? I am allergic to soy, dairy, wheat, fish and am a vegetarian. Thanks
None: There are no foods, vegetarian or non-vegetarian that would increase these hormones. ...Read more
Here's a nice wikihow on this topic:
http://www. Wikihow. Com/increase-dopamine. Some foods high in tyrosine are almonds, avocados, bananas, low-fat dairy, lima beans, sesame seeds and pumpkin seeds. Limit refined carbohydrates - sugar and flour. Eat a diet high in antioxidants to prevent the degradation of dopamine. ...Read more
Dopamine production: There is no proven way to increase dopamine. Ingested Dopamine is broken down in the stomach and small intesting (unless combined with a special medication...Carbidopa, for example in the medicine given to Parkinson's patients carbidopa/levodopa). It can be given intravenously, which is done sometimes to help increase blood pressure. See also: http://en. Wikipedia. Org/wiki/dopamine. ...Read more