Doctor insights on:
Lupron (leuprolide) depot not covered by ins. Pharmacy will not accept medication discount from drug company. Any lower cost alternatives for tx of endometriosis?
Endo: First off, I wouldn't give up so easily. Call the pharmaceutical company and ask for help obtaining your prescription from a different pharmacy. But if that fails, there are other less effective options: Depo-Provera provera, (medroxyprogesterone) continuous low dose birth control pills, and danocrine. And, I've seen people get pain relief from acupuncture! also an herbal supplement called "pine bark extract" may help. ...Read more
I was on Depo Lupron (leuprolide) for 3mnths which ended Dec 2013.I wanna conceive. Does that medication would interfere with conception now? My mens is normal now
My 7 year old daughter has been diagnosed with cpp and her doctor wants to start her on lupron (leuprolide) depot ped 7.5mg monthly. How safe is this medication?
No time limit: It really depends upon its benefit to your husband. Men with metastatic disease can have long term benefit. ...Read more
I read the drug Lupron (leuprolide) can be given to make young women grow taller. Will it also cause height to grow in adult women (over 35) if taken for IUIs?
Can drugs in IVF make endometriosis worse? If yes, what is the solution to get pregnant and deal with endo? How can Depo-Provera lupron (leuprolide) help?
Endometriosis & IVF: Depo-lupron monthly or 3-month injections are used for women with endometriosis, pelvic pain or fibroids, men with prostate cancer, and children with puberty too young. Subcutaneous injections of leuprolide are used in fertility treatment to prevent ovulation in in vitro fertilization cycles, as a trigger shot for egg donors and ivf patients, and in very low doses for microdose flare ivf protocols. ...Read more
Leuprolide is used to turn of the pituitary from making the hormones-fsh and lh thus turning off ovarian estrogen and Progesterone production (medical menopause).
Using this concept we can reduce pain, bleeding issues, fibroids, abnormal hair growth, precocious growth in adolescents- and in the treatment of infertility.
If one doesn't use "add-back" hormones, one can get hot flashes and bone los. ...Read more
Hormone inhibitor: Lupron (aka leuprolide) inhibits the production of testosterone and estrogen from the testes and ovaries, respectively. It is used in the treatment of a number of things including endometriosis, prostate and breast cancer and inappropriately early puberty in kiddos, each of which is made worse by excessive testosterone or estrogen secretion. ...Read more
Menopausal effects: Lupron (leuprolide) injections are used for many reasons in gynecology, most commonly in the treatment of fibroids and endometriosis. Essentially, Lupron (leuprolide) shuts down ovarian function and leads to a menopausal state. Therefore, side effects include hot flashes, vaginal dryness, mood swings, decreased libido, and bone loss. ...Read more
Depends/ indications: I agree with the prior answer in context, but want to weigh in on other uses. Studies show Lupron (leuprolide) in the depot form is effective at shrinking fibroid volume by about 1/3 in 3 months. This gives a proven statistically lower blood loss in women preparing for surgical myomectomy. Also Lupron (leuprolide) in the non-depot form is safe, effective and routinely used in stimulations for ivf. ...Read more
Lupron is a powerful suppressor of estrogen activity (mediated through the hypothalamus and pituitary), and it is used to suppress symptoms of endometriosis. It has many side effects including hot flashes and bone loss.
Many doctors use this but I do not. It is my professional opinion (and profession) that women with endometriosis would benefit more from expert excision of their disease. ...Read more
After Lupron (leuprolide): A 3.75 lupron (leuprolide) depot dose well generally take a while to wear off. After 4 weeks, the dose should be gone and your would start growing a follicle for the next cycle, if you have regular cycles. Expect a subsequent period about 6-8 weeks after the last injection. The hot flashes usually subside about 4-6 weeks after the last injection. The more doses you have receive, the longer it may take. ...Read more
Varies: There are three forms of lupron, (leuprolide) one is a subcutaneous injection daily which will wear off very quickly. The second type is a depot form which last for approximately 30 days in the body, and lastly there is a 90 day form. A woman will usually ovulate 2 to 4 weeks after the effects of the Lupron (leuprolide) has worn off. ...Read more
Usually: Within 1 cycle or 1 month. Good wishes. ...Read more
By far, the most common side effect is hot flashes, because Lupron (leuprolide) causes a temporary menopause. Poor sleep resulting in emotional side effects or head ache are also common. A serious effect from long-term Lupron (leuprolide) is osteoporosis. Many of these side effects are reduced or eliminated with extra "add-back" hormones.
Some women have no side effects at all. ...Read more
Terrible: Lupron (leuprolide) causes reversible menopause. So as soon as the medicine takes effect the estrogen drops to zero same as complete menopause. Hot flashes, night sweats, moods, memory issues and joint pain etc. Many dr. S use this for endometriosis but endo is a surgically treated disease. Lupron (leuprolide) only temporarily diminishes symptoms but makes people miserable. Excisional surgery is needed via laparoscopy! ...Read more
Endometriosis. ..: Depo-lupron monthly or 3-month injections are used for women with endometriosis or chronic pelvic pain, men with prostate cancer, and children with puberty too young. It may be used to shrink uterine fibroids before surgery. Depo-lupron is used in fertility treatment to prevent ovulation in frozen embryo transfer cycles & egg donor recipients, and can be used before ivf in women with endometriosis. ...Read more
Lupron for what?: Need more information. For what problem are you on Lupron? What symptoms are you having that are not going away on Lupron. Best wishes! ...Read more
Assume Pelvic Pain: ? Diagnosis endometriosis and pain. If Lupron (leuprolide) is not helping, the pain is either coming from very severe endo, or from another source. A common associated pain is from the inguinal region and is often associated with endo. Surgery to correct this relieves pain in more than 80%. There are other potential causes of pain that should be evaluated. Seek pelvic pain/endo specialist for more help. ...Read more
1 or 3 months: Lupron (leuprolide) comes in 1 or 3 month doses (3.75 or 11.25 mg) and these injections usually cause menopause symptoms which I've seen as both mild or severe. It rarely continues beyond the treatment period & is a good way to pre-treat or reverse endometriosis or to shrink fibroid tumors prior to surgery. Discuss with your doc if your symptoms are severe or if you need estrogen to counter the severe effects. ...Read more