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Doctor insights on: Leukotriene Inhibitor

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Dr. Jeffrey Satinover
16 doctors shared insights

Leukotriene Inhibitor (Overview)

Leukotriene inhibitors are a kind of asthma drug (lung drug).


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Asthma question. How do leukotriene inhibitors work?

Asthma question. How do leukotriene inhibitors work?

Prevention: Leukotriene is one of chemical mediators responsible for airway inflammation and bronchospasm leading to airway obstruction when asthma flares up. Singulair (montelukast) and accolate, known as leukotriene inhibitors, therefore prevent or reduce flare-ups. ...Read more

Dr. Jeffrey Satinover
16 doctors shared insights

Leukotriene Inhibitor (Overview)

Leukotriene inhibitors are a kind of asthma drug (lung drug).


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Just started on enalapril 5.0 mg (vasotec) it is an ACE inhibitor. I - is that a possible side effect if pregnant?

Just started on enalapril 5.0 mg (vasotec) it is an ACE inhibitor. I - is that a possible side effect if pregnant?

Yes: All ace inhibitors cause fetal abnormalities including cranial malformation and kidney problems in a large percentage of fetuses who are exposed although not 100%. It is absolutely critical you not take this medication while pregnant. A few doses early in pregnancy are less likely to be harmful. All these drugs carry a "black box warning", that is they are dangerous in pregnancy. ...Read more

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What are the side effects of pump inhibitor medcine?

What are the side effects of pump inhibitor medcine?

Few: Most common side effects are on the label or insert. Most are not common. You can find them on the web at sites such as pub med health.Watch for any drug interactions with your other medications. ...Read more

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Asthma question. How do leukotriene inhibitors work?

Prevention: Leukotriene is one of chemical mediators responsible for airway inflammation and bronchospasm leading to airway obstruction when asthma flares up. Singulair (montelukast) and accolate, known as leukotriene inhibitors, therefore prevent or reduce flare-ups. ...Read more

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If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

If u get a steroid tendon inj & r taking a cyp450 3a4 inhibitor at the same time is it like getting 3 steroid injections?

No: It is still one steroid injection. Biotransformation in liver is important for drugs given trough mouth, im and IV since those effect depend on concentration of drug in blood. Liver (and p450 enzyme system) has relatively little effect on drugs injected in joints, epidural space, tendons, body cavities. ...Read more

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What are inhibitors? What is the normal level in our body?

Question unclear: Inhibitors of what? Substances which are inhibitors block a physiologic pathway and often there is a balance between stimulators and inhibitors which shifts with body needs. There are also numerous medications which inhibit physiologic or pathophysiological functions. ...Read more

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What are the cox-1 and cox-2 inhibitors? Are they pain blockers?

What are the cox-1 and cox-2 inhibitors?  Are they pain blockers?

No and Yes: Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys. Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker. ...Read more

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Can you tell me examples of enzyme inhibitors?

Can you tell me examples of enzyme inhibitors?

Viagra (sildenafil) !: Sildenafil (Viagra), a common treatment for male erectile dysfunction is a potent inhibitor of cGMP specific phosphodiesterase type 5, the enzyme that degrades the signalling molecule cyclic guanosine monophosphate. ...Read more

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If you take a cyp450 3a4 inhibitor with a cyp4503a4 inducer, what happens?

Complex question!: D, there exists a situation where a single drug acts as both inducer and affected drug, called autoinduction. Carbamazepine and artemisinin are examples of cyp3a4 and cyp2b6 substrates and inducers, respectively, that are known to exhibit autoinduction. Autoinduction is a phenomenon that can occur anytime a drug induces an enzyme which is also predominately involved in its own metabolic clea. ...Read more

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What is a gaba reuptke inhibitor?

What is a gaba reuptke inhibitor?

Anti-convulsant: Some drugs that are used to treat seizures are GABA reuptake inhibitors. GABA is an inhibitory neurotransmitter and has an anti-seizure effect. These drugs reduce the reuptake of GABA into neurons and glia thereby increasing the amount of GABA available to interact with GABA receptors. ...Read more