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Doctor insights on: Leukocytes And Nitrites In Urine

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An at home urine test showed that I have 500+++ leukocytes but no nitrites in my urine. I have no other signs or symptoms. Should I be worried?

An at home urine test showed that I have 500+++ leukocytes but no nitrites in my urine.  I have no other signs or symptoms.  Should I be worried?

Need to evaluate: You may have urinary infection and it would be a good idea to see your doctor for an evaluation and if needed, treatment. ...Read more

Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more

Dr. Buck Parker
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How do i get a high white blood count in my urine but test negative for nitrites and leukocyte esterase?

How do i get a high white blood count in my urine but test negative for nitrites and leukocyte esterase?

UA results: Nitrites indicate bacterial abundance. If negative, then very low grade infection or no infection exists. Leuk esterase indicates leukocyte enzyme release, reflecting battling leukocytes. If neg, then no leuk attack present, or very low grade. So --- leukocytes without infection do appear in urine from interstitial nephritis , usually allergic, or from interstitial cystitis, usually of unknown ...Read more

Dr. Buck Parker
Board Certified, General Surgery
11 years in practice
312.0K people helped
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Dealing with Blood in Urine (Checklist)

Rule out infection as a cause with a urinalysis or culture
Once
Ask your doctor to review your medications in case one is the cause
Once
Rule out kidney stones with your doctor
Once
If male, schedule a prostate exam
Once
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I took @ home AZO urine strip TEST showed hint of purple on leukocyte and neg.on nitrite. Do I need Doc or am I ok. And could it be BV or YI back pain?

I took @ home AZO urine strip TEST showed hint of purple on leukocyte and neg.on nitrite. Do I need Doc or am I ok. And could it be BV or YI back pain?

Urine: as the nitrite is negative you do not have an infection one can see white cells from the skin that get into the urine which can show up positive you do not need to see anybody at this time but if you develop increased frequency, burning on urination or flank pain please see your primary care ...Read more

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39 weeks pregnant back pain last 4 days left middle back, doc said urine routine leukocyte esterase +ve nitrite -ve pus cell 5-7 wbc/hpf, ceftum250x2/d?

39 weeks pregnant back pain last 4 days left middle back, doc said urine routine leukocyte esterase +ve nitrite -ve pus cell 5-7 wbc/hpf, ceftum250x2/d?

OK: Appears you may have a urinary tract infection that your dr is appropriately treating with an antibiotic that is safe in pregnancy. Assure you keep following up with your dr. For any issues or worsening symptoms, etc. Best wishes and good luck with your pregnancy. ...Read more

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Dealing with Blood in Urine (Checklist)

Get urinalysis with a mid-stream catch
Once
Visit PCP or urologist
Once
Follow up with urologist
Once
Note other symptoms, related medical history
Once
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+40 leukocytes in urine but neg for nitrites. ? Been having UTI symptoms but only mild.

+40 leukocytes in urine but neg for nitrites. ? Been having UTI symptoms but only mild.

Culture?: A urine culture should be performed if it hasn't. This can identify a bacterial infection if that is the cause of the leukocytes in the urine. It is possible to have a UTI and have negative nitrites. Leukocytes in the urine can also be caused by inflammation anywhere in urinary tract up to kidneys. ...Read more

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Dealing with Blood in Urine (Checklist)

Go to your PCP have a complete exam urinalysis, a culture sensitivity.
once
If all exams are normal, make a habit to drink a lot of water.
once
Request regular urine checks to see if the blood in your urine persist
once
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Ua showed i was negative for leukocytes. Negative for white blood cells but positive for nitrites and many crystals in urine. Is this normal?

Ua showed i was negative for leukocytes. Negative for white blood cells but positive for nitrites and many crystals in urine. Is this normal?

Clinical symptoms?: It is possible to have a UTI that only shows positivity for nitrites and be negative for wbcs. Studies have shown that when nitrites are positive, a UTI has a strong chance of being present ( = good specificity for the test). Many crystals can be caused by kidney stones or food metabolism issues. ...Read more

Nitrite (Definition)

Comprised of nitrogen & 2 oxygen molecules. Sodium nitrite is used in meat industry to prevent bacterial growth & to maintain the meat's red color (≥ 22mg/kg body weight is toxic); cooking at high heat allows nitrites to combine with Amino Acids to form nitros-amines (carcinogens). It can be converted by many pathways to nitric oxide, a potent vaso-dilator.Amyl nitrite can be used in heart ds. ...Read more

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Dr. Buck Parker
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