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Doctor insights on: Leukocytes And Nitrites In Urine

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Dr. Gurmukh Singh
Board Certified, Pathology
43 years in practice
95M people helped
1

1
An at home urine test showed that I have 500+++ leukocytes but no nitrites in my urine. I have no other signs or symptoms. Should I be worried?

An at home urine test showed that I have 500+++ leukocytes but no nitrites in my urine.  I have no other signs or symptoms.  Should I be worried?

Need to evaluate: You may have urinary infection and it would be a good idea to see your doctor for an evaluation and if needed, treatment. ...Read more

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Dr. Vicken Poochikian
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36 years in practice
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Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more


Dr. Rex Mahnensmith
Board Certified, Internal Medicine
38 years in practice
9M people helped
2

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How do i get a high white blood count in my urine but test negative for nitrites and leukocyte esterase?

How do i get a high white blood count in my urine but test negative for nitrites and leukocyte esterase?

UA results: Nitrites indicate bacterial abundance. If negative, then very low grade infection or no infection exists. Leuk esterase indicates leukocyte enzyme release, reflecting battling leukocytes. If neg, then no leuk attack present, or very low grade. So --- leukocytes without infection do appear in urine from interstitial nephritis , usually allergic, or from interstitial cystitis, usually of unknown ...Read more

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Dr. Vicken Poochikian
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36 years in practice
2M people helped
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Dr. Venkata Vallury
Board Certified, Pediatrics
37 years in practice
649K people helped
3

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I took @ home AZO urine strip TEST showed hint of purple on leukocyte and neg.on nitrite. Do I need Doc or am I ok. And could it be BV or YI back pain?

I took @ home AZO urine strip TEST showed hint of purple on leukocyte and neg.on nitrite. Do I need Doc or am I ok. And could it be BV or YI back pain?

Urine: as the nitrite is negative you do not have an infection one can see white cells from the skin that get into the urine which can show up positive you do not need to see anybody at this time but if you develop increased frequency, burning on urination or flank pain please see your primary care ...Read more

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Dr. John Munshower
Board Certified, Family Medicine
24 years in practice
93M people helped
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4
39 weeks pregnant back pain last 4 days left middle back, doc said urine routine leukocyte esterase +ve nitrite -ve pus cell 5-7 wbc/hpf, ceftum250x2/d?

39 weeks pregnant back pain last 4 days left middle back, doc said urine routine leukocyte esterase +ve nitrite -ve pus cell 5-7 wbc/hpf, ceftum250x2/d?

OK: Appears you may have a urinary tract infection that your dr is appropriately treating with an antibiotic that is safe in pregnancy. Assure you keep following up with your dr. For any issues or worsening symptoms, etc. Best wishes and good luck with your pregnancy. ...Read more

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Dr. Vicken Poochikian
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Dr. Gurmukh Singh
Board Certified, Pathology
43 years in practice
95M people helped
5

5
Urine tests showing increased wbc/leukocytes without nitrites indicate?

Urine tests showing increased wbc/leukocytes without nitrites indicate?

See below: If the diet is lacking in nitrates, lack of nitrite in urine is meaningless. There may be infection with organisms that do not make nitrite, or the infection may be in the urethra. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is in the best position to do that. ...Read more

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Dr. Samuel Lee
Board Certified, Urology
25 years in practice
134K people helped
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Dr. PHILLIP KIM
Board Certified, Family Medicine
9 years in practice
925K people helped
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Urine reagent strips promo to check urine. All normal (including nitrites) except leukocytes. Color between trace(15) and small(70). Uti? No symptoms.

Unlikely: Urine dip is not the most specific test for UTI but when combined with symptoms of burning sensation, cramps, urgency, frequency, hesistancy it enhances the diagnosis. Otherwise without any symptoms, nothing too conclusive i would say. ...Read more

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Dr. Scott Diede
Board Certified, Pediatric Hematology and Oncology
23 years in practice
3M people helped
8

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+40 leukocytes in urine but neg for nitrites. ? Been having UTI symptoms but only mild.

+40 leukocytes in urine but neg for nitrites. ? Been having UTI symptoms but only mild.

Culture?: A urine culture should be performed if it hasn't. This can identify a bacterial infection if that is the cause of the leukocytes in the urine. It is possible to have a UTI and have negative nitrites. Leukocytes in the urine can also be caused by inflammation anywhere in urinary tract up to kidneys. ...Read more

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Dr. Ashu Syal
Board Certified, Pediatric Nephrology and Dialysis
24 years in practice
1M people helped
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Dr. Scott Diede
Board Certified, Pediatric Hematology and Oncology
23 years in practice
3M people helped
10

10
Ua showed i was negative for leukocytes. Negative for white blood cells but positive for nitrites and many crystals in urine. Is this normal?

Ua showed i was negative for leukocytes. Negative for white blood cells but positive for nitrites and many crystals in urine. Is this normal?

Clinical symptoms?: It is possible to have a UTI that only shows positivity for nitrites and be negative for wbcs. Studies have shown that when nitrites are positive, a UTI has a strong chance of being present ( = good specificity for the test). Many crystals can be caused by kidney stones or food metabolism issues. ...Read more

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Nitrite (Definition)

Comprised of nitrogen & 2 oxygen molecules. Sodium nitrite is used in meat industry to prevent bacterial growth & to maintain the meat's red color (≥ 22mg/kg body weight is toxic); cooking at high heat allows nitrites to combine with Amino Acids to form nitros-amines (carcinogens). It can be converted by many pathways to nitric oxide, a potent vaso-dilator.Amyl nitrite can be ...Read more


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Dr. Vicken Poochikian
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