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Doctor insights on: Leukine

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Dr. Sandra Lora Cremers
4 doctors shared insights

Leukine (Overview)

Leukine is a blood and coagulation agent.


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Neulasta (pegfilgrastim) cause white blood cell spike?

Neulasta (pegfilgrastim) cause white blood cell spike?

Yes!!: This is exactly what Neulasta (pegfilgrastim) does. It increases your white blood cell count, and it can sometimes raise it to very high levels. ...Read more

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Dr. Sandra Lora Cremers
4 doctors shared insights

Leukine (Overview)

Leukine is a blood and coagulation agent.


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Are there any side effects of leukine (sargramostim)?

Are there any side effects of leukine (sargramostim)?

Too many 2 count: Very common side effects: abdominal pain, nausea/vomitting, diarrhea, malaise, rash, tingling/numbness, chest pain, and leg/hands edema, fever, and wt loss. There are many more possible side effects and could be more serious but less frequent. This med is only used when absolutely needed such as following bone marrow transplant or chemo etc...Please ask your doc about treatment u get. Good luck. ...Read more

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What is monoclonal gammopathie IgM kappa?

What is monoclonal gammopathie IgM kappa?

Plasma cell disorder: Monoclonal gammopathy refers to an abnormal production of proteins by cells in the immune system (plasma cells) that are growing out of control. It can be one of the signs of myeloma. A hematologist-oncologist can help. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

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Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Mylotarg-cytarabine: Open these links: http://www.Drugs.Com/mtm/mylotarg.Html http://www.Drugs.Com/mtm/cytarabine.Html.

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What is nonclonal mast cell activation disorder?

What is nonclonal mast cell activation disorder?

Newly characterized: It's a mimic for disorders caused by a neoplastic clone of mast cells. This is hematology subspecialist stuff and i would much rather have this than one of the clonal forms. http://www.ncbi.nlm.nih.gov/pubmed/23212667. ...Read more

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Describe polyclonal and monoclonal antibody production?

Describe polyclonal and monoclonal antibody production?

Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more

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Whats imatinib mesylate?

Whats imatinib mesylate?

Enzyme inhibitor: This drug, gleevec, (imatinib) is used to treat chronic myeloid leukemia and gastro-intestinal stromal tumors. It acts by inhibiting and enzyme produced by tumor cells. ...Read more

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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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What is acute myeloid leukemia is?

Marrow malignancy: AML is a bone marrow malignancy characterized by uncontrolled growth of leukemic cells in the bone marrow. It leads to very high white blood cell counts, anemia and thrombocytopenia (low platelets). It is rapidly fatal without prompt diagnosis and treatment. It can be cured in up to about 40% of people. ...Read more

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Plasma cell Myeloma Myelogram test shows- Plasma cell=24% No haemoparasites seen Leucopoisesis-More active with Plasmacytosis?

Need more info: From what you stated, you have a serious disorder of the bone marrow and should consult a hematologist. The subject cannot be adequately addressed in this forum. ...Read more

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What is IgA kappa monoclonal protein?

What is IgA kappa monoclonal protein?

IgA paraprotein: An IgA kappa monoclonal protein represents a single clone of bone marrow cells that have reproduced in an aberrant fashion. If this is what is found on immunofixation then a hematologist should be consulted for further workup. ...Read more

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What is acute myeloid leukemia (aml)?

What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

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Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?

Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?

Asking what?: If your are requesting a diagnosis online, this is not the appropriate venue. Though the flow cytometry results are not totally normal, your results should be reviewed with the physician who ordered it. This format does not give us the ability to determine if your clinical presentation and lab results are consistent with a specific diagnosis. ...Read more

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What's acute myeloid leukemia?

What's acute myeloid leukemia?

See links: For a nice overview of aml, see the following pages at the national cancer institute. For adult: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient for pediatric: http://www.Cancer.Gov/cancertopics/pdq/treatment/childaml/patient. ...Read more

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Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

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M spike in.Urinie protine alpha 2?

M spike in.Urinie protine alpha 2?

An M spike in either: The urine or the serum reflects the production of a single (monoclonal) globulin. It is found in multiple myeloma, a malignancy of the plasma cells that make antibody, and also can be found in so-called monoclonal gammopathy of unclear significance (mgus) which is generally benign. ...Read more

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IgA lambda monoclonal gammopathy meaning?

IgA lambda monoclonal gammopathy meaning?

It is a medical diso: A medical disorder where your body is making excess of proteins(Gamma Globulins). It can manifest in 2-3 different ways(MGUS or Multiple Myeloma). So you need your doctor to explain which of these conditions do you have and theen get further testing, monitoring and you may or may not need treatment depending on whether it is mGUS(early) or Myeloma(later developemnt...that is a type of Blood Cancer ...Read more

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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Is plasma cell myeloma hereditary?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:

Majority Not: Majority of myeloma cases is not hereditary. A small but unknown fraction of cases are familial. The risk of developing myeloma is approximately 3.7-fold higher for persons with a first degree relative with myeloma. ...Read more

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LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

LP Done. Monocytes 1%, Serum IgG 587/mg/DL,Albumin 4100ml,IGG Index 1.1mg,WBC 23/mm3,RBC 1/mm3, CSF IGG 3.6 mg/DL,Lymphocytoid 97%, protein, neutrophils, glucose, CSF albumin all norm. Any ideas?

CSF Results: If I am reading the results correctly, there appears to be a mononuclear pleocytosis with normal protein, glucose and essentially normal immune response. The fluid analysis cn be seen in many disorders including viral meningitis. Need additional information. ...Read more

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Dr. Scott Keith
3 doctors shared insights

Sargramostim (Definition)

Sargramostim is a ...Read more