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Only sometimes...: I agree cll is not curable for most patients. For some patients who are robust, a consultation at a marrow /stem cell transplant center is warranted as there are investigational approaches that have helped some patients, some who appear cured. A note of caution- bone marrow transplant is the riskiest thing one can do to try to treat this disease and may lead to earlier death though. ...Read moreSee 3 more doctor answers
Scans and biopsy: Patients may have a lump(s) or feel quite ill with fever, night sweats, weight loss and/or anemia which brings them in to the ED or md. Many times blood tests and scans/x-rays are done which lead to a suspicion of lymphoma. A biopsy is required to prove that indeed the patient has lymphoma and also to tell exactly what type of lymphoma they have. ...Read moreSee 1 more doctor answer
Very good: Most people diagnosed with CML today are treated with imatinib or a similar drug like nilotinib or desitanib. These medications will often put people into remission. If you obtain a cytogenetic/molecular and hematologic remission people often live for years. The biggest risk is transformation to an aggressive leukemia, though this does not frequently occur. Many factors determine prognosis. ...Read more
Yes. Survival among: Leukemia patients is influenced by many things, including phenotype, molecular features, presenting white count, patient age, etc. We are making strides every day, with survival improvements across the board. But a leukemia diagnosis does not mean you should give up hope for a long and meaningful survival. For some patients/leukemias survival is near 95%. Be hopeful as you move forward. ...Read moreSee 1 more doctor answer
One Day At A Time: I don't think there is any more devastating news than hearing the word cancer. A few generalizations: 1-throw away any preconceived notions--everyone's cancer is different 2-knowledge is power: the more (accurate)info you get, the better. Good websites include the american cancer society and the national cancer inst. 3-choose a dr. Who you can communicate with 4-take it 1 day at a time. Good luck. ...Read more
Can Philadelphia chromosome positive Chronic Myeloid Leukemia turn into Pre-B-Acute Lymphoblastic Leukemia?
Multiple: Leukemia can present with multiple signs and symptoms including but not limited to: bone pain, refusal to bear weight, gum bleeding, bleeding from other sites, pallor, lack of appetite, fever, night sweats, unexplained weight loss, easy bruising, fatigue, etc. If a concern for leukemia exists the diagnosis is confirmed with blood and bone marrow tests. ...Read moreSee 1 more doctor answer
AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read moreSee 2 more doctor answers
Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read moreSee 1 more doctor answer
CML: We have several medications now to treat this and there is typically a high response rate. The most common drug used is called imatinib but there are 2 others that are approved for first line treatment, Dasatinib and nilotinib. It also depends on the stage, chronic or blast phase. Hope this helps. ...Read more
SCID: Scid stands for severe combined immunodeficiency. By definition, people with this disorder have no t cells, so they cannot fight any diseases or produce any antibodies. Iga is one type of antibody, so a deficiency of it would be expected as part of the scid disorder. This disorder is fatal in infancy without aggressive management, so not likely to be diagnosed in an adult. Cvid more likely. ...Read more
Hello doctor my father was diagnosed with Myelodysplastic Syndromes can he be treated by bone marrow transplant?
Yes, but...: To answer your question, yes, bone marrow transplant is a treatment option for MDS but is not usually the immediate choice. MDS is a very broad spectrum of diseases and each case is unique, thus there are many considerations before deciding on the best therapy approach. Sorry to hear about your father. Below is a link for more information about treatments for MDS. http://bit.ly/2iADlYQ ...Read more
Varies: I am sorry to hear about your mother's illness. There is no easy answer on this--i have seen spans of weeks to years. A lot has to do with her pre-illness condition, amount of weight loss, symptoms, time in the hospital. I try in my own practice to emphasize "quality of life" as more important than "quantity of life." i have seen people do better than expected; maintain realistic hope. ...Read more
See below...: Chronic lymphoblastic leukemia does not exist. Cll stands for chronic lymphocytic leukemia. Lymphoblastic leukemias are acute.The only known complete cure for cll is stem cell transplantation; however, many patients do not need any form of therapy unless there are symptoms or adverse prognostic factors. Cll is usually not an aggressive form of leukemia and has a relatively good prognosis overall. ...Read moreSee 2 more doctor answers
If a person has AML - acut emyeloid leukemia, what percent of blast would suggest acute myeloblastic leukemia?
Blasts in blood/marr: Blasts are made in the bone marrow. Normally they are under 5% of all the white cells. So a Blast count in the bone marrow over 6% raises the question of Acute leukemia. Anything >30% blast count confirms a diagnosis of acute leukemia. As the blast cell numbers increase in the marrow, Blasts start to appear in the peripheral blood. That is how Leukemia is first diagnosed. ...Read more
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