Doctor insights on:
Lesions Bone Myeloma
I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
3 yrs lytic bone lesions through axial skeleton -skull. Extramedullary hematopoiesis. New MRI spots on brain-bone marrow expansion. Can this be fatal?
Depends: Bone marrow expansion throughout the skeleton typically signals either that the marrow is i appropriately expanding into these compartment such as in a myeloproliferative disorder or the present regions of marrow production are insufficient to keep up with current body needs. Regardless of the cause this is best answered by hands on evaluation, testing and management by an hematologist. ...Read more
Inside bone/tendons.: Bone cysts r contained inside the bone, any where from simple benign @ malignant and need watching. Spurs r at the edges of the bone as in arthritis, or in response 2 tendinitis where a tendon attaches. As patellar tendinitis or where ligaments attach as in heel spurs ( planter fasciitis). Treatments r different 4 each & multiple 4 each. B followed & rx'd by an orthopedic surgeon. ...Read more
Usually a bone: Biopsy is done on a a bone with a symptom (pain) and an x-ray abnormalitity (dissolved bone. Lytic; sclerotic, bone, blastic) indicating metastasis or fracture. The biopsy can obtain tissue if the source is occult. A bone marrow biopsy is done to assess anemia, look for leukemia, and sometimes another marrow disorder. ...Read moreSee 1 more doctor answer
Very: Multiple myeloma a plasma cell cancer could be very dangerous in some , in others ( the lucky ones ) the diseases can run for years. Have to speak to the treating oncologist good prognostic signs are higher albumin, lower beta 2 microglobulins, , plasma cell dna showing not having high risk chromosomal abnormalities. ...Read moreSee 1 more doctor answer
Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more
Do Standard99m Tc bone scans with tracer ever reveal lytic lesions of Myeloma, or only ever osteoblastic lesions, and fracture? Having workup for MM.
Bone scan, not helpf: Bone lesions of myeloma do not show up on a Bone scan. So it is not a useful test when looking for bone lesions which can be seen more easily with MRI scan. Alternatively a CT scan can help in a localised spot and PET scan can also be useful in certain select situations. ...Read moreSee 1 more doctor answer
Do not know: There are multiple different types of bone marrow tumors and the cause for almost all is unknown. A few things like exposure to benzene and radiation do predispose a person to leukemia. You may consult this site for info: http://www.mayoclinic.org/diseases-conditions/leukemia/basics/causes/CON-20024914 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more
It depends: If done by an experienced health care worker(doctor/nurse) the bone marrow biopsy can be tolerable(mild to moderate amount of pain). They use local anesthesia which controls 90% of the pain. So i would not worry too much about it and get it done. Just make sure that the person doing the biopsy has done more than 20 biopsies before and does them fairly frequently(>1 per month). ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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