Doctor insights on:
Yes: Shave biopsy can provide enough tissue to make a diagnosis of melanoma although it is not recommended because it can make it difficult to determine the depth of melanoma invasion, accurately. A re-biopsy(wide excision) is recommended to make sure that the residue cells left behind can be adequately excised. ...Read more
Yes, quite often: A dermatologist is an expert at recognizing abnormalities in the skin. Skin lesions can be benign, suspicious and malignant. Their skill is to determine which lesions require definitive treatment from those that can be observed. An examination involves a carefully administered protocol to best serve your skin needs. ...Read more
Not necessarily: That is why it is called an indeterminate lesion. Best is to have your physician discuss with the radiologist who read it for their best opinion and then see an orthopedist who specializes in tumors. If appropriate, a biopsy is sometimes needed to determine the exact cause. Good luck! ...Read moreSee 1 more doctor answer
Usually a bone: Biopsy is done on a a bone with a symptom (pain) and an x-ray abnormalitity (dissolved bone. Lytic; sclerotic, bone, blastic) indicating metastasis or fracture. The biopsy can obtain tissue if the source is occult. A bone marrow biopsy is done to assess anemia, look for leukemia, and sometimes another marrow disorder. ...Read moreSee 1 more doctor answer
Pigmented lesion ..Back...Biopsy sheets dermoepidermal junction nests pigmented bland looking round cells &nuclei.......Whats diagnosis plz?
Sounds benign: This description sounds like a benign mole or what a pathologist would call a junctional nevus. There should be a final diagnosis on the report in addition to the description. Doesn't sound worrisome or atypical to me. ...Read more
Follow up imaging: Imaging results need follow up with your doc to obtain meaning. Hypoechoic and hyperdense are words that describe appearance on ct image. They are not a diagnosis. Your doc will discuss the imaging results with you. You may need a biopsy to get diagnosis. Take a friend with you to see your doc. ...Read more
May i know the simple explanation for this diagnosis: (post auricular area), excision biopsy: cellular spindle cell lesion favor nodular fascitis?
Get 2nd opinion: A pathologist who trained at one of my institutions self-diagnosed a sarcoma and had his arm amputated, only to discover later it was nodular fasciitis, which is very benign. I was trained by some of the great pathologists and even they said they'd never call nodular fasciitis without a second pathologist agreeing. I'd suggest showing 3-4 of us pathologists. Good luck. ...Read more
Please explain: 5 CM irregular splenic lesion. Differential diagnosis lymphoma and splenic metastasis. Could this be cancer?
Yes: Both are forms of cancer. It could also be a benign hemangioma, an epidermoid cyst, an infart (how's your overall vascular health?) or any of a number of other entities. What to do next will depend on your history and physical exam. You're in no immediate danger but this very much needs to be followed up. Many of the lymphomas especially are very curable with today's biotech. ...Read more
Recent diagnosis w/autoimmune disease & skin biopsy result: urticaria or mast cell disease. Shouldn't biopsy give more definitive diagnosis?
Hard to tell: Mast cells are the cells that release histamine in the body. This is what happens in urticaria, so one will see mast cells in biopsies of urticarial (hive-like) lesions. Mast cells can also be found in increased numbers in people with mastocytosis. Thus the biopsies may be similar. As stated by my colleague, the clinical history can be key to the diagnosis. Talk with your doc. ...Read moreSee 1 more doctor answer
Myxofibrosarcoma presenting in the skin: clinicopathological features and differential diagnosis with cutaneous myxoid neoplasms.?
Fairly common: The differential diagnosis will be made by the pathology team. My teacher hector battifora was among the world's most distinguished sarcoma pathologists but said he would never sign one out without another pathologist. The low nuclear grade ones rarely metastasize / kill, but all are prone to annoying local recurrences. Good luck, glad it's this relatively tame (still dangerous) cancer. ...Read more
CT Brain shows mass prepontine cistern CPA meningioma. Symptoms consistent with diagnosis. MRI contrast show no lesion. Symptoms persist! Now what?
Very strange: Not certain what to make of the disparity between the CT scan and the MRI. In some cases, a lesion is so small that it is missed by the artifact created by the thickness of the MRI slices. I would ask your doctor if an MRI of the brainstem with "thin slices" might be reasonable to confirm/refute the CT--with and without contrast. Take care and stay healthy! ...Read more
Thyroid follicular lesion 2.4cm solid circumscribed with mild vascularity.Thyroseq pending Can this test show a definite benign? what's circumscribed
Pigmented lesion . In face..Recent increase size..Irregular border....Biopsy reveals malignant cells infiltration ...Whats diagnosis plz?
Pathology: A "mass" can be anything including non-cancer. A piece of tissue from a mass (or bone marrow biopsy, or blood) placed on a glass slide for a pathologist to review with special stains and sometimes molecular tests can give a "tissue diagnosis". With very few exceptions (eg, hcc, germ cell cancer) oncologists require a "tissue diagnosis" before treating cancer. ...Read moreSee 1 more doctor answer