Doctor insights on:
Lentigo Malignant Melanoma
A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more
Another option: This year was amazing for finally having some options to treat mm, including ipilimumab and also vemurafenib. Early diagnosis by getting screened by a board-certified dermatologist is essential to having the highest cure rate. Check yourself and your partner monthly and get to the derm if you notice any new or changing spot! ...Read more
Varies: It depends on depth of melanoma at time of excision and whether any lymph nodes are involved. Early melanomas less than. 75 millimeters have close to a 100 per cent survival. Dpeer melanomas greater than 1 mom, then greater 2 mm, and 3 mm. Have lower per cent age of 5 year cure rate. There are 2 new drugs for advanced melanomas. Early treatment is essential. ...Read more
Depends on depth: The prognosis for melanoma depends greatly on the stage at diagnosis. In the absence of spread to lymph nodes or other sites, the depth of the melanoma is the most important factor which predicts outcome. The deeper the tumor invades the more risk of it spreading/recurring. I caught early, melanoma is very curable. Discuss the case in question with your dermatologist or oncologist. ...Read more
Studies are underway: There are studies currently underway of this drug in certain cases of stage IV melanoma. It is only available in a research studies, in certain locations, and only patients who meet strict entry criteria are eligible. Patients and families can find these studies listed at www. Clinicaltrials. Gov ...Read more
I have read that desmoplastic neurotrophic malignant melanoma is a less dangerous type to have. Is this true?
Malignant melanoma: There are no good malignant melanomas but the size thickness location and lymph nodes are the best predictors of survival. ...Read more
No evidence: Standard of care is surgical resection for early stages. For unresectable stage 3 or metastatic stage 4, treatments can be chemotherapy (dacarbzine or temodar), or immunotherapy such as interleukin-2, or ipilimumab. Targeted drugs for braf-positive melanoma are zelboraf, tafinlar, or mekinist. Enroll in a clinical trial is highly recommended. No evidence that oncothermia by itself is effective. ...Read more
This technique of heating tumor has been used in melanoma in a very limited way. One way, in the past was to isolate the vessels of a leg and pump heated chemotherapy through it. It had limited success.
The recent exciting treatment through targeted therapy and control of the immune system have made oncothermia less interesting in melanoma in the us. ...Read more
Skin mole: Melanoma doesn't usually hurt or cause symptoms. Sometimes it itches or bleeds easily. If it is very large it can cause pain. If it has spread to other organs it can also cause symptoms. But if it is small and just on the back, it doesn't cause much in the line of symptoms. Visit your doctor to talk about your options to determine if it really is melanoma (punch biopsy or shave biopsy). ...Read more
Skin cancer: Malignant melanoma is a cancer that begins usually in the pigmented cells (melanocytes) of the skin. It is generally considered the most dangerous form of skin cancer. Most cases are localized and caught fairly early but some people will develop widespread metastatic disease and die. ...Read more
My husbands brother had malignant melanoma, is there an increased chance that he would get it? Or our children?
I have what looks like the beginning stages of malignant melanoma, but I can't be sure. I don't have health insurance. What are my options?
Controversial: A very good question, and the answer is not clear. Some experts believe that pregnancy increases the risk of melanoma and advise women with a melanoma history to avoid pregnancy, or at least wait several years. Others say the evidence to support that recommendation is not convincing. Until we have a definite answer I would be very cautious; if you get pregnant, have your skin examined frequently. ...Read more
Usually surgery: Assuming that the melanoma has not spread to other organs, the first treatment is to surgically remove the affected skin with a rim of normal skin. Then, certain patients will also need to have an operation to remove 1 or more lymph nodes depending on the spread. In select cases, melanoma that has spread to other organs is surgically removed. Other patients will need chemotherapy and radiation. ...Read more
I had malignant melanoma in 1994. What are the chances of it recurring. Should I still get annual skin check-ups.
I have malignant melanoma in radial stage with minimal microscopic invasion. Could this have spread already, I am waiting for wide excision.
Information: Radial grownth phase is probably better than vertical. Melanomas less that 1mm thick have excellent prognosis. The pronosis depends primarily on thickness. Other factors include ulceration, lymphocytic response, regression, tumors in the 1-4mm range benefit from sentinal node biopsy. ...Read more
No best treatment: Vaginal melanoma is considered mucosal disease and this type tends to spread via the blood to other organs in the body more readily. There is no known best treatment for stage iic. However, based on a recent study, chemotherapy with Cisplatin and temodar (temozolomide) every 3 weeks for 6 cycles are reasonable. However, enrolling in a clinical trial if available is the best option. ...Read more
Does a completely removed potential precursor to malignant melanoma atypical nevus return in same place? Does it return as a malignant melanoma?
No: If it was removed completely, it will not return. This is why it's good to take margins. If it does recur at the site, it will probably still be a benign lesion, but keep an eye on it. The most important thing about a diagnosis of atypical nevus is that it warns you're likely to get a melanoma someplace else. Keep an eye on all your skin (partner, dermatologist) and quick removal will save you! ...Read more
Malignant melanoma is a cancer that begins usually in the pigmented cells (melanocytes) of the skin. It is generally considered the most dangerous form of skin cancer. Most cases are localized and caught fairly early but some people will develop widespread ...Read more