Doctor insights on:
Methotrexate cheaper: Generic Methotrexate is very inexpensive. If you get name brand pills it's more, but generic version of Arava (leflunomide) is more expensive than Methotrexate and Arava is the most expensive. In my experience, Methotrexate works better and has less frequent dosing (weekly instead of daily). I only use Leflunomide (arava) if Methotrexate can't be used for some reason. Side effects are similar. ...Read more
Allergy or side -: Allergy or side effect? Rash, hives, facial swelling-these are manifestations if allergy! Low white count, gastric issues, and hepatitis are examples of potentially serious side effects. This drug should be prescribed by only a handful of specialists who use it frequently! ...Read more
Multiple answers: Allergies or what I consider side effects to Arava can range from diarrhea to a skin rash which are common problems related to Arava. Hair loss, abdominal pain, and elevated liver function tests are also common side effects Many other issues can be seen with the drug and be found in the product information. Good luck ...Read more
If you have been: If you are pregnant on arava, (leflunomide) you need to notify your prescribing doctor immediately and you may need to see a high risk ob. ...Read more
Common combination: In rheumatoid arthritis Prednisone is given with a variety of other medication during therapy. We try to taper people off Prednisone because of its long term risks and side effects. Each medication has side effects including some of these: risk of infection, bone loss, osteoporosis, cataracts, weight gain with Prednisone and blood count and liver test with (leflunomide) generic name of arava. ...Read more
Why do I need to stop methotrexate & arava (leflunomide) before alif surgery? I can't take it for 2 months after, why?
It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more
What are my chances of getting liver disease while taking arava (leflunomide) and methotrexate together?
See details: Studies of this combination have shown increased risk of liver disease over taking just one of these meds alone. The exact risk is open to debate. I personally never prescribe this combination of meds although other rheumatologists do. ...Read more
On enbrel 50mg weekly for 3 mos, methotrexate 25mg weekly 3mos, arava (leflunomide) 20mg 1 month, still have psoriasis lesions. Is this possible&willl psor. Ever clear?
Still a bit early:
So many of these medications requires several weeks or months to start working. Enbrel and Arava usually works around 3 months after starting it, and Methotrexate can take as long as 6 months before working.
I would give it another month, then reconsider. There are other good medicines that could work for you including stelara (ustekinumab). ...Read more
Hello doctor I suffer from rhumatoid. I am on emthexate2.5 (8pills once a week) and arava leflunomide (a pill every two days) my liver aches. Thank u?
Severe liver injury: Including fatal liver failure, has been reported in some patients treated with arava (leflunomide). Patients with pre-existing acute or chronic liver disease, or those with serum alanine aminotransferase (alt) > 2xuln before initiating treatment, should not be treated with arava (leflunomide). Use caution when Arava (leflunomide) is given with other potentially hepatotoxic drugs. Also emthexate2.5 have liver sisde effects but as much. ...Read more
Taking arava (leflunomide) been on it 3 weeks two of those I have loose clay colored stools should I call my dr now or wait for my appointment in two months?
Call now: Symptoms may or may not be related to the medication, but don't wait. ...Read more
I have psa im on embrel 50mg weekly leflunomide 20mg daily pednisone 10mg daily. Still crippling pain what else can I do? Tryd mtx remicade (infliximab) humara
Alt high 60, AST high 45 on methotrexate 25mg, arava (leflunomide) 20mg, enbrel weekly. Should I be concerned? Never had pblm.
Talk to your doctor: Those are not terribly high lab values for alt and ast. Such modestly elevated labs that measure liver irritation (or damage/disease when > 2-3 times the upper limit of normal) can be temporarily caused by common viral infections, alcohol consumption, or interactions with other meds that affect the liver. Getting labs checked within 48hrs of Methotrexate can also result in higher lab values. ...Read more
Can arava (leflunomide) be prescribed for lupus? What is the best medication for sle lupus when liver and kidneys are affected? Thank you very much.
Not really: In my experience it has little or no value. The liver is not involved in lupus so look for other causes. With renal disease, a biopsy is essentially and CellCept (mycophenolate mofetil) would be the drug of choice. ...Read more
My mom, 60, is on methotrex 10 mg per week and leflunomide 10 mg/day for her r.A. For 1 year. Does she require folinic acid or is folate (folic acid) 5mg/day ok?
Spinal fusion 9 weeks ago, RA 13yrs, on mtx, plaquinil & arava, (leflunomide) still not under control. Would biologics interefere with bone growth? Have bone stimulat
Perhaps: Several medications used to treat RA can interfere with bone growth. You should talk to both your rheumatologist and to your surgeon about what you are taking and whether it should be stopped or changed while your bones are fusing. ...Read more