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Doctor insights on: Leflunomide

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Dr. James Lin
33 doctors shared insights

Leflunomide (Overview)

Leflunomide is an immune system affecting agent.


Dr. James Lin
33 doctors shared insights

Leflunomide (Overview)

Leflunomide is an immune system affecting agent.


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Can leflunomide cause bleeding?

Can leflunomide cause bleeding?

If?: It can lower platelets. If liver problems (hepatitis occurs, lower fibrinogen levels occur and can also cause bleeding. Low platelet counts are more likely. ...Read more

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Is there anyone out there prescribing leflunomide for inflammatory arthritis?

Is there anyone out there prescribing leflunomide for inflammatory arthritis?

Yes: The labeled use for Leflunomide is the treatment of rheumatoid arthritis but it has also been used in various types of inflammatory arthritis including psoriatic arthritis and undifferentiated inflammatory arthritis. It is not used for osteoarthritis. ...Read more

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Psa have tried mtx w /remicade& w/ humara no help methotrexate caused blood issues but worked better. Now embrel/leflunomide.No relief frustrated help?

Psa have tried mtx w /remicade& w/ humara no help methotrexate caused blood issues but worked better. Now embrel/leflunomide.No relief frustrated help?

MTX sc ?: Mtx causes less liver issues given sc versus oral. Also mtx has more potent metabolites that take 10 weeks to develop. You did not specify what tests where abnormal. But you suggest that mtx was given alone. Was it? Mtx and Humira (adalimumab) are a good combo for psoriatic arthritis. ...Read more

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Is it safe to take leflunomide while pregnant?

Is it safe to take leflunomide while pregnant?

Ideally No: Leflunomide is used in rheumatoid arthritis. It can cause fetal birth defects. Generally we want to get you off of this medication prior to pregnancy. You should talk to your doctor before coming off of any medication however. ...Read more

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Is there anyone on leflunomide for inflammatory arthritis?

Is there anyone on leflunomide for inflammatory arthritis?

Yes!: It vis what I use next after s.C. Methotrexate, inn most situations where the drug is important! it is potentially more toxic (liver), but appropriate monitoring should minimize any risk. It is a potent and good anti-inflamatory drug. ...Read more

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Are many people with RA taken off leflunomide?

Are many people with RA taken off leflunomide?

Some: The main reasons people are taken off Leflunomide is that the drug doesn't work for them or that it causes a side-effect. Sometimes Leflunomide is no longer needed because another drug is treating the rheumatoid arthritis so well. ...Read more

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Where can I buy arava (leflunomide)?

Where can I buy arava (leflunomide)?

Rx only: Arava is a prescription drug for rheumatoid arthritis. It needs to be prescribed and monitoring by a physician familiar with its use. Arava or the generic, leflunomide, can be purchased through most pharmacies and long term distribution pharmacies. ...Read more

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Can leflunomide cause bleeding?

If?: It can lower platelets. If liver problems (hepatitis occurs, lower fibrinogen levels occur and can also cause bleeding. Low platelet counts are more likely. ...Read more

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Are many people with RA taken off leflunomide?

Some: The main reasons people are taken off Leflunomide is that the drug doesn't work for them or that it causes a side-effect. Sometimes Leflunomide is no longer needed because another drug is treating the rheumatoid arthritis so well. ...Read more

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Is arava (leflunomide) cheaper then methotrexate?

Is arava (leflunomide) cheaper then methotrexate?

Methotrexate cheaper: Generic Methotrexate is very inexpensive. If you get name brand pills it's more, but generic version of Arava (leflunomide) is more expensive than Methotrexate and Arava is the most expensive. In my experience, Methotrexate works better and has less frequent dosing (weekly instead of daily). I only use Leflunomide (arava) if Methotrexate can't be used for some reason. Side effects are similar. ...Read more

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Could leflunomide cause bleeding to the back passage?

Could leflunomide cause bleeding to the back passage?

Not unless....: If the drug causes a low platelet count, it can cause or promote bleeding anywhere. I have not seen this in my rheumatology practice, having many arthritis and psoriasis patients on this! ...Read more

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Is it safe to take leflunomide while pregnant?

Ideally No: Leflunomide is used in rheumatoid arthritis. It can cause fetal birth defects. Generally we want to get you off of this medication prior to pregnancy. You should talk to your doctor before coming off of any medication however. ...Read more

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Is there anyone on leflunomide for inflammatory arthritis?

Yes!: It vis what I use next after s.C. Methotrexate, inn most situations where the drug is important! it is potentially more toxic (liver), but appropriate monitoring should minimize any risk. It is a potent and good anti-inflamatory drug. ...Read more

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What is the definition or description of: Leflunomide allergy?

Allergy or side -: Allergy or side effect? Rash, hives, facial swelling-these are manifestations if allergy! Low white count, gastric issues, and hepatitis are examples of potentially serious side effects. This drug should be prescribed by only a handful of specialists who use it frequently! ...Read more

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What is the definition or description of: Arava (leflunomide) allergy?

What is the definition or description of: Arava (leflunomide) allergy?

Multiple answers: Allergies or what I consider side effects to Arava can range from diarrhea to a skin rash which are common problems related to Arava. Hair loss, abdominal pain, and elevated liver function tests are also common side effects Many other issues can be seen with the drug and be found in the product information. Good luck ...Read more

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I have RA and am on prednsion and arava, (leflunomide) what do you think?

Seems ok: These are known treatments for rheumatoid arthritis. They are not typically the first agents that I use and i like to try to get my patients off all steroids if i can, but I do have patients on Leflunomide (arava) if they can't take or fail Methotrexate or biologicals. ...Read more

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What are the chances of arava (leflunomide) harming a baby while pregnant?

Quite serious: Leflunomide is category X by the FDA, the highest rating for potential for birth defects. If pregnant a doctor must follow a strict protocol outlined by the FDA. There are to date no major studies regarding pregnancy outcome in actual patients. ...Read more

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What's the probability of arava (leflunomide) harming a baby while pregnant?

What's the probability of arava (leflunomide) harming a baby while pregnant?

If you have been : If you are pregnant on arava, (leflunomide) you need to notify your prescribing doctor immediately and you may need to see a high risk ob. ...Read more

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Dr. Andrew Berry
28 doctors shared insights

Arava (Definition)

Arava is an ...Read more