Doctor insights on:
Lazy Leg Syndrome
What's the best medicine for rstless leg syndrome. I won't sleep more that a hour or two and it starts again, please help me?
My preference: From a safety and side effect point of view is horizant. This's is an extended release form of gabapentin. Although Lyrica (pregabalin) did slightly better in a recent study, it is not approved for this. Also, Lyrica (pregabalin) carries a considerable risk of weight gain. Antiparkinson's drugs work but sometimes eventually cause the symptoms to worsen during the day. Klonopin can be helpful. ...Read more
What is RLS?: Restless Leg is a condition where you have an uncomfortable sensation (burning, crawling, cramping, aching, tingling, etc.) in you legs that cause an urgent/irresistible need to move your legs (walking, moving legs, messaging, rubbing, etc.). This movement usually occurs when going to bed and can progress to the daytime and sometimes to the arms. See a movement disorder neurologist for Treatment. ...Read moreSee 3 more doctor answers
Multiple: Dopamine agonists work best and include ropinorole, pramipexole, the new Neupro (rotigotine) patch. More traditional meds have included l-dopa, and clonazepam. If you have anemia or kidney disease, better treatment of these conditions may work. Check serum ferritin as some folks may have issues with iron metabolism. Rls is occasionally associated with ms>. ...Read moreSee 2 more doctor answers
NOT FULLY KNOWN: But do find some patients with disruption of iron stores, so, can check ferritin levels. We do find some problem with dopamine issues, and find success in using dopamine agonists, but another approach using Horizant, affects different brain chemicals. May be some genetic links in a few families, and association with a sleep disorder in some also found. ...Read more
Dopamine lack: I think restless leg syndrome is probably caused in susceptible people (tends to be familial) by a relative lack of sufficient Dopamine and is often associated with fatigue, dopamine-blocking medicines, chronic illness, and the end of gestation. Medications that increase Dopamine are frequently helpful as can be Neurontin (gabapentin) and Klonopin (clonazepam).. ...Read moreSee 1 more doctor answer