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Doctor insights on: Large Platelets

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What are the common causes of large platelets and hypersegmented neutrophils?

What are the common causes of large platelets and hypersegmented neutrophils?

Vitamin & leukemias.: Hypersegmented neutrophils are seen with vitamin b-12 and folate (folic acid) deficiency, while large platelets can be in myelophthisic disease, like myelofibrosis and leukemias. These are conditions that displace the precursor cells from the bone marrow into the peripheral blood. ...Read more

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Help docs! i'm trying to find out what causes large platelets and hypersegmented neutrophils?

Help docs! i'm trying to find out what causes large platelets and hypersegmented neutrophils?

Maybe two things?: Platelets that are a little bit above or below reference range size seldom mean anything if the platelet count itself is normal and there's nothing to suggest compensated autoimmunity. Hypersegmented neutrophils suggest B12 or Folic Acid deficiency from some cause as the first possible problem worth checking. ...Read more

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My 16 year old son has platelet count 255 and mean platelet volume 11.0 with a comment large platelets present. What could be the cause of that?

My 16 year old son has platelet count 255 and mean platelet volume 11.0 with a comment large platelets present.  What could be the cause of that?

Not significant.: Mpv is mean platelet volume. Younger platelets tend to be larger than older ones, so sometimes it means increased platelet turnover, but unless the platelet count is low, a high mpv has no meaning. Some people just make larger platelets. ...Read more

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What does Low and large platelet mean along with patchy T1 hypointensity within the marrow from my MRI?

What does Low and large platelet mean along with patchy T1 
hypointensity within the marrow from my MRI?

More info needed: Low and large platelets may be associated with a decreased platelet count and production of new larger platelets. What is the platelet count? Which bone marrow area is being patchy--this could be associated with decreased circulation or fibrosis in that area of the marrow. Please discuss with your doctor who ordered these tests. ...Read more

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SLIDE REVIEW results, anisocytosis 1+,microcytes 1+,normochromic,ovalocytes occasional,toxic granulation 2+,toxic vacuoles 1+,large platelet 1+Whado?

Clinical picture: The real question is, how do you feel? These findings, while abnormal, may never be explained. In isolation, apart from the clinical picture, they are meaningless. I trust the reader is a pathologist or hematologist -- I'm the former, and often remind people that labs, while indispensable, are adjuncts to the clinical findings. ...Read more

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What does it mean if you have some large platelets on blood test? My absolute lymphocyte count is 0.5 lymphocyte 4% neutrophils 86% WBC 12.6

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your neutrophil count is high suggesting an infection. "Some large platelets" is not a cause for concern. ...Read more

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Mri cervical spine states patchy T1 hypointensity within the marrow. Blood tests shows large platelets and 91 platelet count What does this mean?

Mri cervical spine states patchy T1 
hypointensity within the marrow. Blood tests shows large platelets and 91 platelet count What does this mean?

Needs medical attent: I assume you have a doctor taking care of you. if not seek one, you may actually need to see a hematologist provided a repeat Platelet count shows low platelet count. Platlet counts under 150,000 are considered low. There can be many causes for it. You need to do a CBC(complete blood count) and send us the results. This might give a clue. But further testing will be required if platelets remain lo ...Read more