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Doctor insights on: Large Granular Lymphocytic Leukemia

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What sort of problem is acute non-lymphocytic leukemia (a.N.L.L.)?

What sort of problem is acute non-lymphocytic leukemia (a.N.L.L.)?

AML: Acute myelogenous leukemia (AML) is a type of leukemia that usually present relatively rapidly, but in some cases may have a longer development phase. It may be preceded by mds. Treatment is often stratified by age and co-morbidities but can include intensive chemotherapies and allogeneic stem cell transplant. ...Read more

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Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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What is a karyotype for acute lymphocytic leukemia?

What is a karyotype for acute lymphocytic leukemia?

A karyotype is ...: A technique that lets us see the gross structural features of the chromosomes in a cell. Cells are forced to enter mitosis but then are arrested in metaphase with a drug called nocodazole. The chromosomes can the be seen under the microscop which lets is see their number and structure. All cells can have multiple abnormalities that can be seen by karyotype, but may be normal as well. ...Read more

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What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

CLL: Cll is a clonal disorder (cancer) of the white blood cells (specifically lymphocytes) in the blood (= -emia part). Other leukemias include cml, aml, all, etc. Cll is often diagnosed by flow cytometry on peripheral blood. Additional studies may include ct scans and bone marrow biopsy. One staging system is rai 0 to iv. Treatment ranges from observation (rai 0-1) to various tx individualized to pt. ...Read more

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Chronic lymphocytic leukemia is a very slow disease?

Chronic lymphocytic leukemia is a very slow disease?

Can be: Based on the genetic factors of the leukemia (cll) it can be a slow-growing disease that may not require therapy for a long time, if ever. ...Read more

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Is there a karyotype for acute lymphocytic leukemia?

Is there a karyotype for acute lymphocytic leukemia?

Yes: Chromosomal abnormalities, such as t(9;22)(q34;q11) (abl/bcr), t(12;21)(p13;q22) (tel/aml1), and t(11q23) (mll) are independent prognostic indicators in childhood acute lymphoblastic leukemia. ...Read more

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What're the effects of chronic lymphocytic leukemia?

See below: Cll is form of blood cancer, usually a slowly progressing one. It may cause fever, enlarged lymph nodes, weight loss, anemia etc. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001559/. ...Read more

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How to determine chronic lymphocytic leukemia stages?

Your oncologist can: Ask your treating doctor. The stages of cll are based on the extent of disease which requires both blood tests as well as physical exam and ct scans of the chest and abdomen to look for lymph node enlargement and or splenomegaly. ...Read more

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What does chronic lymphocytic leukemia do to your body?

What does chronic lymphocytic leukemia do to your body?

Depends on the stage: In early case, patient will be asymptomatic and the only thing abnormal is the blood test. In later stage- one can have low blood counts (anemia, low platelet), fatigue , tired, lack of energy, bruising easily/bleeding also, you could feel lymph nodes enlargement on the neck, arm pits, groin etc as cll involves more to the lymph nodes. Increase abdominal girth, fever, chils, weight loss can happen. ...Read more

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What causes people to get chronic lymphocytic leukemia?

What causes people to get chronic lymphocytic leukemia?

Mostly unknown: Cll affects older white men more that other parts of the population and the cause is unknown in most cases. Exposure to certain herbicides and insecticides, including agent orange used during the vietnam war, have been linked to an increased risk. For more information consult: http://www.Mayoclinic.Com/health/chronic-lymphocytic-leukemia/ds00565/dsection=risk. ...Read more

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Is likely that chronic lymphocytic leukemia (cll) live?

A form of cancer: Cll is a form of cancer, albeit a slowly progressing one and there are effective treatments. See this site for more information. http://www.mayoclinic.com/health/chronic-lymphocytic-leukemia/ds00565. ...Read more