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Doctor insights on: Large Granular Lymphocytic Leukemia

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What sort of problem is acute non-lymphocytic leukemia (a.N.L.L.)?

What sort of problem is acute non-lymphocytic leukemia (a.N.L.L.)?

AML: Acute myelogenous leukemia (AML) is a type of leukemia that usually present relatively rapidly, but in some cases may have a longer development phase. It may be preceded by mds. Treatment is often stratified by age and co-morbidities but can include intensive chemotherapies and allogeneic stem cell transplant. ...Read more

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Dr. Liawaty Ho
1,098 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

CLL: Cll is a clonal disorder (cancer) of the white blood cells (specifically lymphocytes) in the blood (= -emia part). Other leukemias include cml, aml, all, etc. Cll is often diagnosed by flow cytometry on peripheral blood. Additional studies may include ct scans and bone marrow biopsy. One staging system is rai 0 to iv. Treatment ranges from observation (rai 0-1) to various tx individualized to pt. ...Read more

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Help! what is acute lymphocytic leukemia in a chronic stage?

Help! what is acute lymphocytic leukemia in a chronic stage?

I believe you have: These diagnoses confused. Chronic leukemias display an elevated # of wbcs with morphologic and functional features similar to the mature cells of that lineage (lymphoid-cll vs myeloid-cml). Think of it as not turning off the spigot when the bucket is full. Acute leukemias have features of immature cells for a lineage (aml vs all). Acute leukemias can arise from chronic ones. This is blast crisis. ...Read more

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What is a karyotype for acute lymphocytic leukemia?

What is a karyotype for acute lymphocytic leukemia?

A karyotype is ...: A technique that lets us see the gross structural features of the chromosomes in a cell. Cells are forced to enter mitosis but then are arrested in metaphase with a drug called nocodazole. The chromosomes can the be seen under the microscop which lets is see their number and structure. All cells can have multiple abnormalities that can be seen by karyotype, but may be normal as well. ...Read more

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How long can someone in there early 40s with chronic lymphocytic leukemia live? Another 20 years?

How long can someone in there early 40s with chronic lymphocytic leukemia live?  Another 20 years?

Possible, but varies: The prognosis of chronic lymphocytic leukemia (cll) depends on factors such as the genetics of the cll and the stage among other things. With good prognostic signs some patients with cll can have an average survival of at least 10 years and many will live for 20 or more years. On the other hand the disease can be more aggressive with adverse indicators. ...Read more

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What is the definition or description of: chronic lymphocytic leukemia ivgh?

What is the definition or description of: chronic lymphocytic leukemia ivgh?

A test 2 assess risk: The correct name is igvh mutational status assay. This is a gene test performed only on leukemic cells of patients with cll to assess risk of progression, and death from cll. The readout is either mutated (which is favorable) or unmutated (unfavorable). Igvh mutations happen during the normal generation of antibodies in white cells. ...Read more

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Chronic lymphocytic leukemia is a very slow disease?

Chronic lymphocytic leukemia is a very slow disease?

Can be: Based on the genetic factors of the leukemia (cll) it can be a slow-growing disease that may not require therapy for a long time, if ever. ...Read more

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I have chronic lymphocytic leukemia. What can I do to fight against this disease?

I have chronic lymphocytic leukemia. What can I do to fight against this disease?

Options available: There are a lot of treatment options available. However not everybody with cll need to get treated right away at the first initial diagnosis. There are some indications to start one on therapy. Nowadays, treatment is personalized and tailored to the biology of the cancer. There are some prognostic/predictive markers that can be tested to guide treatment selection, discuss with your oncologist. ...Read more

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My friend found out she has acute lymphocytic leukemia today. What can she expect?

Chemotherapy: All is generally curable in children, less so in adults. See this site for more info. http://www.mayoclinic.com/health/acute-lymphocytic-leukemia/ds00558. ...Read more

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Can someone in there early 40s with early chronic lymphocytic leukemia get cured?

See below...: The only known complete cure for cll is stem cell transplantation; however, many patients do not need any form of therapy in the beginning and treatment is only started if the patient develops symptoms or adverse prognostic factors are present. Cll is usually not an aggressive form of leukemia and has a relatively good prognosis overall. ...Read more

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