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Doctor insights on: Large Cell Neuroendocrine Carcinoma In Bone Tissue

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What is a small cell neuroendocrine carcinoma?

What is a small cell neuroendocrine carcinoma?

Aggressive tumor: Small cell lung cancer is a neuroendocrine carcinoma that exhibits aggressive behavior, rapid growth, early spread to distant sites, exquisite sensitivity to chemotherapy and radiation, and frequent association with distinct paraneoplastic syndromes, including hypercalcemia Frequently goes to brain for which prophylactic RT given ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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What are the symptoms of neuroendocrine carcinoma?

What are the symptoms of neuroendocrine carcinoma?

Varied: Nfeouroendocrine tumors represent a large array of lesions representing small cell and larege cell tumors. Medullary ca of thyroid is a large cell neuroendocrine presenting as a neck mass. Small cell neuroendocrine of lung metastasizes to brain. Gi neuroendocrine tumors spread to liver ie carinoid, producing flusing and other hormone symptoms. ...Read more

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Is there anything that causes high grade neuroendocrine carcinoma of the liver?

Is there anything that causes high grade neuroendocrine carcinoma of the liver?

Not known: Neuroendocrine carcinomas that originate in the liver are very rare ( about 200 reported cases in english literature). Intestinal neuroendocrine carcinomas that metastasize to the liver are more common, but still rare compared to the usual adult tumors. We do not know what causes any of these tumors. ...Read more

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High grade neuroendocrine carcinoma of liver?

High grade neuroendocrine carcinoma of liver?

There are treatments: The vast majority of neuroendocrine carcinomas in the liver originate in another site. Since the liver disease is the most common contributor to survival, we will often use liver directed therapies to control the liver component of the disease. There is an imaging techinque (ga68) used in europe that is available in certain centers in the us that can help evaluate the ds and response to trtment. ...Read more

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Can you tell me about neuroendocrine carcinoma cancer?

Can you tell me about neuroendocrine carcinoma cancer?

Where's the primary?: Neuroendocrine carcinomas tend to be quite aggressive and are often more difficult than the more common cancers arising at the same site. If you can let us know where it arose (cervix, pancreas, some other?), we can help you out. ...Read more

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What is a neuroendocrine carcinoma cancer?

What is a neuroendocrine carcinoma cancer?

Interesting cancer: This is a type of cancer that mostly arises either from the small intestine, pancreas, or lung. They are unusual because some can produce certain hormones which cause symptoms like weight gain or weight loss, or diabetes, or diarrhea depending on which hormone is produced. If caught early, many are curable with surgical removal. The abbreviation is "NET" and another name is a carcinoid tumor. ...Read more

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What amount chances of survival of neuroendocrine carcinoma of the cervix?

What amount chances of survival of neuroendocrine carcinoma of the cervix?

It all depends: Survival of this disease depends on a number of factors. The stage of the disease is very important to know. Stage defines the extent of disease. Higher stage means more advanced disease which means a worse prognosis. Neuroendocrine carcinoma is not very common in the cervix. It is a more aggressive cell type than the more common squamous cell carcinoma. ...Read more

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Please tell how much chances of survival of neuroendocrine carcinoma of the cervix?

Please tell how much chances of survival of neuroendocrine carcinoma of the cervix?

Small cell : Neuroendocrine carcinoma of the cervix is rare, accounting for < 3% of cases, so there optimal treatment is not known. With current treatments, the 5 year likelihood of survival is about 50%, however the stage of the tumor (size, invasion into surrounding normal tissue, spread outside the cervix) is very important, and could adjust that number up or down depending on how advanced the tumor is. ...Read more

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What is the best treatment for metastatic neuroendocrine carcinoma?

Tricky to answer: Metastatic neuroendocrine carcinoma is a heterogeneous group of tumors with variable aggressiveness. Depending on the primary site, different treatment options exist, including liver directed treatments to liver involvement or systemic chemotherapy if the primary is pancreatic. The prognosis is based on location, pattern of spread, and grade. ...Read more

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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Barry Rosen
4,121 doctors shared insights

Cancer (Definition)

An uncontrolled cell growth leading to invasion and metastases is what cancer is defined as. It produced abnormal growth of cells which acquire destructive properties causing serious threat to host's life, unless it can be removed or destroyed by ...Read more