Doctor insights on:
Large Cell Neuroendocrine Carcinoma In Bone Tissue
Aggressive tumor: Small cell lung cancer is a neuroendocrine carcinoma that exhibits aggressive behavior, rapid growth, early spread to distant sites, exquisite sensitivity to chemotherapy and radiation, and frequent association with distinct paraneoplastic syndromes, including hypercalcemia Frequently goes to brain for which prophylactic RT given ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
Varied: Nfeouroendocrine tumors represent a large array of lesions representing small cell and larege cell tumors. Medullary ca of thyroid is a large cell neuroendocrine presenting as a neck mass. Small cell neuroendocrine of lung metastasizes to brain. Gi neuroendocrine tumors spread to liver ie carinoid, producing flusing and other hormone symptoms. ...Read more
Not known: Neuroendocrine carcinomas that originate in the liver are very rare ( about 200 reported cases in english literature). Intestinal neuroendocrine carcinomas that metastasize to the liver are more common, but still rare compared to the usual adult tumors. We do not know what causes any of these tumors. ...Read moreSee 1 more doctor answer
There are treatments: The vast majority of neuroendocrine carcinomas in the liver originate in another site. Since the liver disease is the most common contributor to survival, we will often use liver directed therapies to control the liver component of the disease. There is an imaging techinque (ga68) used in europe that is available in certain centers in the us that can help evaluate the ds and response to trtment. ...Read moreSee 1 more doctor answer
Interesting cancer: This is a type of cancer that mostly arises either from the small intestine, pancreas, or lung. They are unusual because some can produce certain hormones which cause symptoms like weight gain or weight loss, or diabetes, or diarrhea depending on which hormone is produced. If caught early, many are curable with surgical removal. The abbreviation is "NET" and another name is a carcinoid tumor. ...Read more
It all depends: Survival of this disease depends on a number of factors. The stage of the disease is very important to know. Stage defines the extent of disease. Higher stage means more advanced disease which means a worse prognosis. Neuroendocrine carcinoma is not very common in the cervix. It is a more aggressive cell type than the more common squamous cell carcinoma. ...Read more
Small cell : Neuroendocrine carcinoma of the cervix is rare, accounting for < 3% of cases, so there optimal treatment is not known. With current treatments, the 5 year likelihood of survival is about 50%, however the stage of the tumor (size, invasion into surrounding normal tissue, spread outside the cervix) is very important, and could adjust that number up or down depending on how advanced the tumor is. ...Read more
Is it possible to have metastasis Neuroendocrine Carcinoma , does not show in CT but show on octreotide scan, area like Small intestine , Liver ?
Yes: The OS is one of the definitive test for mets of neuroendocrine tumors ...Read more
Tricky to answer: Metastatic neuroendocrine carcinoma is a heterogeneous group of tumors with variable aggressiveness. Depending on the primary site, different treatment options exist, including liver directed treatments to liver involvement or systemic chemotherapy if the primary is pancreatic. The prognosis is based on location, pattern of spread, and grade. ...Read moreSee 1 more doctor answer
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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