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Doctor insights on: Lactic Acidosis Differential

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Dr. Ayo Adu Dr. Adu
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What's lactic acidosis?

Dr. Ayo Adu Dr. Adu
1 doctor agreed:
What's lactic acidosis?

Lactate + low pH: Lowered ph in your blood accompanied with a build-up of lactate. ...Read more

Dr. Bernard Seif
37 doctors shared insights

Lactic Acidosis (Definition)

Lactic acidosis is the buildup of lactic acid in the blood, either from an increase in the body's production or the kidney being unable to remove lactic acid effectively. The most common causes are intense exercise (increased production of lactic acid) or kidney failure (unable to effectively remove lactic acid from blood). Other causes include blood infections (sepsis) and inability to ...Read more


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How are respiratory acidosis and metabolic acidosis different?

How are respiratory acidosis and metabolic acidosis different?

The source: Respiratory acidosis is the result of co2 build up in the blood, metabolic acidosis is the result of inability to remove acids or the addition of acids to the system. ...Read more

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Respiratory acidosis and metabolic acidosis, which is worse?

Worse acidosis: Both a respiratory (r) and metabolic acidosis (m) are bad. A r is due to retention of carbon dioxide (c) and a m is due to the presence of an organic acid. The treatment of a r is to reduce the c, blowing of c and the treatment of a m is to get rid of of the organic acid. ...Read more

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What causes diabetic keto acidosis?

Dka: Diabetic ketoacidosis is a condition whereby glucose which is used by cells for energy is not made available to the cells due to a lack of insulin. The lack of Insulin causes a dramatic rise in blood sugar triggering a host of meatbolic derangemants including dehydration as well as the production of ketones which are toxic as it raises the bodies acid level and will affect potassium levels. ...Read more

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What symptoms characterize metabolic acidosis?

See below: Metabolic acidosis can be detected by blood teasts. Patients can present with kussmauls breathing which is deep ventilation or breathing. Some patients have abdominal pain blood tests show a low bicarbonate (sodium bicarbonate) level and a low co2 level seen on blood gases.This is a serious condition with many causes, commonly seen with diabetic ketoacidosis. ...Read more

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I'm confused, what is lactic acidosis?

Dangerous condition: The body generates energy by breaking down fat and sugar thru a very efficient mechanism that uses oxygen and produces carbon dioxide and water. When this mechanism fails, there is another inefficient back up system that generates lactic acid. Poor blood flow, low oxygen, medications, poisons, excessive exercise can cause this lactic acidosis. It should be corrected promptly. ...Read more

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Why does respiratory alkalosis cause hypokalemia while metabolic acidosis causes hyperkalemia?

K and alkalosis acid: Blood K is sensitive to blood pH.( hydrogen ion concentration). When H gets too high (acidosis) it moves into cells to protect from death from too much acid.. As H+ moves into cells a + ion must move out. This is usually K+. Thus hyperK. When H+ gets too low (alkalosis) in blood H+ moves from cell to blood to prevent death from low H+.. As H+ moves out of cell K+ moves in. Thus blood K goes down. ...Read more

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What is high anion gap metabolic acidosis?

Metabolic acidosis: A high anion gap acidosis, (h), is an acidosis with a low carbon dioxide (c) and a normal chloride. This low c indicates the presence of an organic acid, such as lactic acid. H is seen in sepsis and diabetic ketoacidosis, among other conditions. It is a serious condition that requires immediate medical therapy to resolve it, as it is often life-threatening. ...Read more

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How common is lactic acidosis with sepsis?

How common is lactic acidosis with sepsis?

With septic shock: It is a marker for end organ damage due to inadequate oxygen reception or utilization. When sepsis progresses to shock we will follow lactate (its pka is 4, so its never really acid in the blood) as a marker of our success in getting blood and oxygen to the peripheral tissues. So... In sepsis itself (without shock) it is rare, but in septic shock lactate is almost always elevated. ...Read more

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Severe infection causes metabolic acidosis or dka?

Yes!: Particularly in individuals with Insulin deficit, ie. Type 1s, or type 2's with aging pancreatic islet cell atrophy! ...Read more

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How can diabetic ketoacidosis (w/ metabolic acidosis) causes respiratory failure?

Due to acidosis.,,: The metabolic acidosis causes a respiratory compensation in an attempt by the body to keep the blood ph normal. The respiratory compensation is to increase minute ventilation (both respiratory rate and volume per breath!). So, the person with severe metabolic acidosis will be breathing fast and deeply. Doing this for an extended period of time can lead to fatigue resulting in respiratory failure. ...Read more

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Is serum Osmolality typically elevated in metabolic acidosis/alkalosis and ethylene glycol poisoning?

Yes: Particularly with ethylene glycol poisoning. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Normal CBC, CMP & electrolytes. Does this exclude acid/base problems such as metabolic acidosis or alkalosis??

Sort of: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, just the fact that you are asking this question is sufficient to conclude that you do not have serious acid/base disorder. ...Read more

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Does food change lactic acidosis levels?

Yes: Many foods are acidic in nature and so anything acidic can make an acidosis worse. Alkaline diets (increasing avocado, kale, spinach, cucumber, celery for example) can help balance and acidic condition. Meats are very acidic, by the way. ...Read more

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How does high chloride cause a (non-anion gap) metabolic acidosis?

See below: Please consult this site for the information. It is more involved than the 400 characters will allow. http://emedicine.medscape.com/article/240809-overview ...Read more

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What causes low serum bicarbinate and urea?

What causes low serum bicarbinate and urea?

Metabolic panel: Urea could be low without any significance, sometimes seen in liver failure malnourishment. There could be other rare causes. . Low bicarbonate (sodium bicarbonate) could from a number of causes depending on the context. Discuss this with your doc. ...Read more

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What does this mean "high anion gap metabolic acidosis"?

Anion gap: The anion gap is a calculation in which you subtract the sum of the negative ions in the blood (chloride, bicarbonate) from the sum of the positive ions (sodium, potassium). Often potassium is left out because it has only a very small effect. A normal gap is < 11. If the result of the subtraction is > 11 you have a high anion gap acidosis, which means some other acid is causing acidosis (ketoacids. ...Read more

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Can dehydration lead to metabolic acidosis?

It usually does: The contraction of the fluid volume caused by dehydration routinely leads to a metabolic acidosis as the metabolism begins to shift to more fat breakdown & those byproducts add to the acidity of the blood.Fluid expansion through oral or IV re-hydration can correct this quickly by exposing the blood to buffer compounds in the tissues. ...Read more

Dr. Ayo Adu Dr. Adu
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What's lactic acidosis?

Dr. Ayo Adu Dr. Adu
1 doctor agreed:

Lactate + low pH: Lowered ph in your blood accompanied with a build-up of lactate. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more