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Doctor insights on: Lactic Acidosis

Lactic acidosis: Most cases of type a lactic acidosis are due to marked tissue hypoperfusion in shock or during cardiopulmonary arrest. In type b lactic acidosis, systemic tissue hypoperfusion is not apparent. Metformin therapy for type ii diabetes can cause it, although the likelihood of this is relatively low. Risk factors for this include impaired kidney function and liver disease or concurrent alcohol abuse. ...Read more

Yes: Many foods are acidic in nature and so anything acidic can make an acidosis worse. Alkaline diets (increasing avocado, kale, spinach, cucumber, celery for example) can help balance and acidic condition. Meats are very acidic, by the way. ...Read more

Lactic acidosis: Severe lactic acidosis (la) is often associated with poor prognosis. Recognition and correction of the underlying process is the major step in the treatment of this serious condition. Intravenous administration of sodium bicarbonate (sb) has been the mainstay in the treatment of lactic acidosis. Dialysis, peritoneal in particular, can also be used in some cases to avoid a massive sb load. ...Read more

Pancreatitis : No medication is safe. However you should consult with your endocrinologist if you are unsure about taking this medication. ...Read more

Lactic acidosis: Although accumulation of Lactic Acid in muscles during anaerobic exercise may cause temporary burning, i don't think your soreness is related to lactic acidosis. It is more likely a result of using muscles that you haven't used for a while. Boxing is very strenuous. Lactic acidosis in hospitalized patients usually results from impaired tissue oxygenation due to tissue hypoperfusion in shock. ...Read more

Lactate + low pH: Lowered ph in your blood accompanied with a build-up of lactate. ...Read more

Lactic acidosis: Severe lactic acidosis (la) is often associated with poor prognosis. Recognition and correction of the underlying process is the major step in the treatment of this serious condition. Intravenous administration of sodium bicarbonate (sb) has been the mainstay in the treatment of lactic acidosis. Dialysis, peritoneal in particular, can also be used in some cases to avoid a massive sb load. ...Read more

Yes: Many foods are acidic in nature and so anything acidic can make an acidosis worse. Alkaline diets (increasing avocado, kale, spinach, cucumber, celery for example) can help balance and acidic condition. Meats are very acidic, by the way. ...Read more

Dangerous condition: The body generates energy by breaking down fat and sugar thru a very efficient mechanism that uses oxygen and produces carbon dioxide and water. When this mechanism fails, there is another inefficient back up system that generates lactic acid. Poor blood flow, low oxygen, medications, poisons, excessive exercise can cause this lactic acidosis. It should be corrected promptly. ...Read more

Unlikely: Theoretically Metformin can cause lactic acidosis but in setting of normal kidney function it is extremely unlikely. Liver disease and concurrent alcohol use can also increase the risk. Talk to your health care provider if you have any of the above risk factors to determine the risk of lactic acidosis. ...Read more

Not a common: Symptom.

Determine cause: Many causes of this. Treatment is directed at the underlying cause. The underlying cause is often apparent from simple review of history and observation of patient. Common causes - hypovolemia, heart failure, sepsis, alcohol, diabetes and metformin.... ...Read more

Lactic acidosis: Please go online to "www.ncbi.nlm.nih.gov/" and look up lactic acidosis and diabetes. It won't be easy reading but worth a look. You can also go to PubMed and search for lactic acidosis and diabetes. Take your time learning about this. ...Read more

See below: La arises from impairment of gluconeogenesis. Lactic acid is generated both in the liver and muscle and is oxidized to pyruvic acid and then converted via the gluconeogenenic pathway to g6p. Accumulation of g6p inhibits conversion of lactate to pyruvate. The Lactic Acid level rises during fasting as glucose falls. In people with gsd i, it may not fall entirely to normal even when gluc levels r nml. ...Read more

Unclear question: High reading of what? What are "symptoms of lactic acidosis"? What did you have the test for? ...Read more

Unusual diagnosis: Caused by production and absorption of d-lactic acid in colon. This occurs when glucose and carbohydrates are delivered to the colon and are metabolized by gram positive anaerobes (lactobacillus). Resulting d- Lactic Acid is absorbed into bloodstream but not broken down by enzymes which only recognize l-lactic acid. So you become acidotic. Episodes of acidemia occur with carbohydrate loads. ...Read more

Z: Does not depend on only metformin dose. Depends on the sugar control and other factors like infection or other comorbid illnesses. ...Read more

Lactic acidosis: Most cases of type a lactic acidosis are due to marked tissue hypoperfusion in shock or during cardiopulmonary arrest. In type b lactic acidosis, systemic tissue hypoperfusion is not apparent. Metformin therapy for type ii diabetes can cause it, although the likelihood of this is relatively low. Risk factors for this include impaired kidney function and liver disease or concurrent alcohol abuse. ...Read more

Unlikely: It is very unlikely to develop lactic acidosis while on metformin unless you have definite renal impairment. You doctor should be able to advise you. ...Read more

Symptoms : All these have manifestation similar but also different. Pain is typically seen in pancreatitis. ...Read more