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Doctor insights on: Lack Vitamin Cause Macrocytic Anemia

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Dr. Steven Ginsberg
1,236 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


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What are the causes of macrocytic anemia for elderly? If no vitamins defficiency, no RBC breakdown, no thyroid and liver problems & normal wbc

What are the causes of macrocytic anemia for elderly?  If no vitamins defficiency, no RBC breakdown, no thyroid and liver problems & normal wbc

See hematologist: As my previous answer, your dad should see a hematologist for his anemia. Work-up including a bone marrow biopsy should be done- one of the thing we should rule out is possibility of myelodysplastic syndrome. However we are not able to give you more specific answer without seeing all the complete result of previous work-up and examining your father. So, start by asking pmd to refer to hematologist. ...Read more

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What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

Depression>poor eatg: Anemia should not be accepted as an inevitable consequence of aging. A cause is found in approximately 80 percent of elderly patients. The most common causes of anemia in the elderly are chronic disease and iron deficiency. Vitamin B12 deficiency, folate (folic acid) deficiency, gastrointestinal bleeding and myelodysplastic syndrome are among other causes of anemia in the elderly. Serum ferritin is the most us. ...Read more

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What is the possible problem for 70 yrs old man with macrocytic anemia. Hb 9, retic count .85% , MCV 108. Vitamins, liver, kidney, wbc, plat. Normal?

What is the possible problem for  70 yrs old man with macrocytic anemia. Hb 9, retic count .85% , MCV 108. Vitamins, liver, kidney,  wbc, plat. Normal?

Macrocytic Anemia: Anemia is due to (a) decreased RBC production, (b) increased RBC destruction, and/or (c) blood loss. Macrocytic RBCs and low reticulocyte count suggest decreased RBC production. Common causes: folate def, B12 def, alcohol, liver disease, hypothyroidism. Less common causes: myelodysplastic syndrome, LGL leukemia, acute leukemia, HBV, HCV, HIV. Drugs can cause MA: Hydrea, (hydroxyurea) zidovudine, etc. ...Read more

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Dad 70 yrs, non alchoholic. Has macrocytic anemia. Hb 10. Mcv 110. No blood loss. Bone marrow, kidney, liver, vitamins, colonscopy normal. Why anemic?

Dad 70 yrs, non alchoholic. Has macrocytic anemia. Hb 10. Mcv 110. No blood loss. Bone marrow, kidney, liver, vitamins, colonscopy normal. Why anemic?

Ideas: He's not on medications and has normal thyroid, correct? He needs a reticulocyte count to determine whether these cells are big because they're young. I'd be surprised if that was the explanation. Next will perhaps be an offer of a bone marrow tap to look for myelodysplastic syndrome. ...Read more

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My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

Labs: How high is the MCV and how low is the Hb? A blood B12 can be misleading in come cases, a more definite test is needed, called Methylmalonic acid acid level along with RBC folate level and not just a pure folic acid level. If they are normal. In some cases a Homcystine level may be needed. Best of luck ...Read more

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What would cause a vitamin B12 deficiencybesides anemia?

What would cause a vitamin B12 deficiencybesides anemia?

Vitamin B12 def: actually it's the other way around, Vit b12 def causes the anemia. B12 def occurs in people who are vegetarian and don't take vitamin supplement, also malabsorption could lead to B12 def, also there is a condition called pernicious anemia which is an autoimmune disease and these patient cannot absorb b12. ...Read more

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I had depression and stopped eating but a bit for six month. My hemoglobis 10.5. All else normal including vitamins? Does depression cause anemia?

No: Your hemoglobin is low, but depression does not directly cause anemia. You need to work with your doctor to discover the cause of this low hemoglobin and treat it. Not eating can result in inadequate nutrition (including vitamins); problems with absorbing nutrients and hidden blood loss can also lead to anemia. ...Read more