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Doctor insights on: Lack Vitamin Cause Macrocytic Anemia

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Dr. Steven Ginsberg
1,275 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more


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What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

What are all the causes of moderate macrocytic anemia in elederly other than vitamin B12 and folic acid defficiency. Can severe depression cause that?

Depression>poor eatg: Anemia should not be accepted as an inevitable consequence of aging. A cause is found in approximately 80 percent of elderly patients. The most common causes of anemia in the elderly are chronic disease and iron deficiency. Vitamin B12 deficiency, folate (folic acid) deficiency, gastrointestinal bleeding and myelodysplastic syndrome are among other causes of anemia in the elderly. Serum ferritin is the most us. ...Read more

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What are the causes of macrocytic anemia for elderly? If no vitamins defficiency, no RBC breakdown, no thyroid and liver problems & normal wbc

What are the causes of macrocytic anemia for elderly?  If no vitamins defficiency, no RBC breakdown, no thyroid and liver problems & normal wbc

See hematologist: As my previous answer, your dad should see a hematologist for his anemia. Work-up including a bone marrow biopsy should be done- one of the thing we should rule out is possibility of myelodysplastic syndrome. However we are not able to give you more specific answer without seeing all the complete result of previous work-up and examining your father. So, start by asking pmd to refer to hematologist. ...Read more

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What is the possible problem for 70 yrs old man with macrocytic anemia. Hb 9, retic count .85% , MCV 108. Vitamins, liver, kidney, wbc, plat. Normal?

What is the possible problem for  70 yrs old man with macrocytic anemia. Hb 9, retic count .85% , MCV 108. Vitamins, liver, kidney,  wbc, plat. Normal?

Macrocytic Anemia: Anemia is due to (a) decreased RBC production, (b) increased RBC destruction, and/or (c) blood loss. Macrocytic RBCs and low reticulocyte count suggest decreased RBC production. Common causes: folate def, B12 def, alcohol, liver disease, hypothyroidism. Less common causes: myelodysplastic syndrome, LGL leukemia, acute leukemia, HBV, HCV, HIV. Drugs can cause MA: Hydrea, (hydroxyurea) zidovudine, etc. ...Read more

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Dad 70 yrs, non alchoholic. Has macrocytic anemia. Hb 10. Mcv 110. No blood loss. Bone marrow, kidney, liver, vitamins, colonscopy normal. Why anemic?

Dad 70 yrs, non alchoholic. Has macrocytic anemia. Hb 10. Mcv 110. No blood loss. Bone marrow, kidney, liver, vitamins, colonscopy normal. Why anemic?

Ideas: He's not on medications and has normal thyroid, correct? He needs a reticulocyte count to determine whether these cells are big because they're young. I'd be surprised if that was the explanation. Next will perhaps be an offer of a bone marrow tap to look for myelodysplastic syndrome. ...Read more

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My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

My dad has normal tests of liver and kidneys. Also normal urine test, vitamin b12, heart, mch, wbc, and no tumor. But got macrocytic anemia. Why?

Labs: How high is the MCV and how low is the Hb? A blood B12 can be misleading in come cases, a more definite test is needed, called Methylmalonic acid acid level along with RBC folate level and not just a pure folic acid level. If they are normal. In some cases a Homcystine level may be needed. Best of luck ...Read more

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What would cause a vitamin B12 deficiencybesides anemia?

What would cause a vitamin B12 deficiencybesides anemia?

Vitamin B12 def: actually it's the other way around, Vit b12 def causes the anemia. B12 def occurs in people who are vegetarian and don't take vitamin supplement, also malabsorption could lead to B12 def, also there is a condition called pernicious anemia which is an autoimmune disease and these patient cannot absorb b12. ...Read more

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I had depression and stopped eating but a bit for six month. My hemoglobis 10.5. All else normal including vitamins? Does depression cause anemia?

I had depression and stopped eating but a bit for six month. My hemoglobis 10.5. All else normal including vitamins? Does depression cause anemia?

No: Your hemoglobin is low, but depression does not directly cause anemia. You need to work with your doctor to discover the cause of this low hemoglobin and treat it. Not eating can result in inadequate nutrition (including vitamins); problems with absorbing nutrients and hidden blood loss can also lead to anemia. ...Read more

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Is it possible to have anemia without having abnormal cbc? Also can low vitamin d cause it?

Is it possible to have anemia without having abnormal cbc?
Also can low vitamin d cause it?

Not possible: Anemia is diagnosed by low blood hemoglobin or hematocrit on cbc. Can be due to low red blood cell count or low serum iron. Low vitamin d can be corrected by taking vitamin d 1000 u tablets & or fish liver oils capsules. ...Read more

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47yr old f with anemia. Taking iron and centrum vitamins but still feeling very sleepy and tired...What can be the cause?

47yr old f with anemia. Taking iron and centrum vitamins but still feeling very sleepy and tired...What can be the cause?

As above : If she still anemic or have another medical or mental issues , than it is normal to feel that . It is important to do a detailed evaluation to r /o medical abd mental health issues . In addition excersize may improve her energy. ...Read more

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What can cause angular cheilitis besides anemia or vitamin deficiency?

What can cause angular cheilitis besides anemia or vitamin deficiency?

Many things: Classically vitamin B12 or iron deficiency is the text book answer, but in the us today, this type of inflammation is more often caused by topical trauma, such as wind, cosmetics, or mouth pieces used in some sports. Some medicines cause the mouth and lips to become dry, and occasional allergic reactions to meds or foods have been reported. ...Read more

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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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What might cause high B12 levels? I also had low iron (long-standing anemia) and low vitamin D. CBC was normal except mildly low hemoglobin.

B12 normal range: There is no harm in an elevated B12 level. The normal range is established based on a population study, but the physiology and diet factors that might lead to higher levels than those in the population study are not significant. Don't worry about it in the least. Get follow-up to see that the hemoglobin comes back to normal though. ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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A positive ANA test, vitamin d deficient, anemia, body aches, and high sed rate. Could all of these symptoms be caused from celiac?

A positive ANA test, vitamin d deficient, anemia, body aches, and high sed rate. Could all of these symptoms be caused from celiac?

No: Celiac disease can cause vitamin d deficiency and anemia, but it's not associated with a positive ANA test. Most patients with celiac have a normal sed rate. Vitamin d deficiency is often associated with myalgia. Celiac disease is an autoimmune disease, and having one autoimmune disease increases your chances of having another one, such as lupus, which can explain your posiitve ANA and body aches. ...Read more

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