Doctor insights on:
Lab Tests For Ovarian Cancer
Annual exam: The best screening remains the annual pelvic exam coupled with a careful history. The ca125, ova-1 and other tumor markers in conjunction with a vaginal probe ultrasound are useful in some patients. Always report any unusual symptoms to your gynecologist. Pay attention to your body. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
History: Including family history, physical exam with pelvic looks at ervix, and bimanual exam, & rectal exam to probe for masses, shelf, and overt and secret blood. Then begins imaging: u/s, ct. If a mass is confirmed, it needs biopsy. Only after DX is made is a ca-125 potentially helpful, not as a screen. ...Read more
I'm 34 and 4 years ago I had all the tests for ovarian cancer it was negative. I now have all the symptoms, could I be in the late stages of it now?
You can not be so su: If you have symptoms, then an examination by your doctor is the first step. Only if he/she suspect something on an examination will they order imaging studies with an ultrasonogram or ct scans which can easily show the status of your ovaries. I would not get so anxious right away when your previous testing has been unremarkable. It may simply be fear/ worry of the unknown. Your doctor can help. ...Read more
None: Unfortunately, no screening test (be it ultrasound, physical exam, or ca 125 tumor marker) can detect ovarian cancer early enough to make a difference. People with high risk for cancer often choose to have the ovaries removed before they get malignant. If you have concerns about your risk, please have a chat with your doc. Best to you. ...Read more
Nothing good: Unfortunately there is nothing that's accurate. We sometimes use ultrasound and a blood test called CA125 to screen very high risk people like those with a family history of ovarian/breast cancer or Ashkenazi Jewish. However, even in this group we are not very good at preventing ovarian cancer and making people live longer. There are some tests in development and hopefully it will be reality soon ...Read more
Backward: There is no screening test for ovca. However, if you have ovarian cancer, a ca-125 level may or may not be elevated. If it is, it may be one thing monitired for response. Getting ca-125, an expensive blood test of unproven value before knowing you have the cancer is inded backward, costly, non-specific and can led to unnecessary worry. ...Read more
Yes: Anybody can have cancer. The basis of diagnosis is the history, physical exam, and rational screening. I do not know what blood work you had, or whether the marker was above reference range or not. This question needs to be brought by you to, and answered by, your personal physician. I'm glad you're taking a proactive approach and wish you good luck on follow-up. ...Read more
I have all the symptoms of ovarian cancer. Had a blood test and it was negative and my scan turned out negative too. So what is the matter?
Ovarian cancer: More often than not, ovarian cancer does not have symptoms. If your scan and blood tests are negative, obviously one must consider other causes. If you separately list your symptoms here, we might be able to help. Even better might be a consult via HealthTap Prime or Healthtap Concierge. Whatever we can do to help. Good luck. ...Read more
Who should get genetic cancer tests? My grandmother had ovarian cancer in her late 60’s but my mom and aunt are both healthy no cancer in their 60’s?
BRCA testing: While no genetic testing is 100% you would qualify for genetic cancer screening based on a maternal grandmother with ovarian cancer. Various companies offer this. My favorite is the Myrisk test from Myriad. You can check it out here: https://myriad. Com/patients-families/your-questions-about-disease/whats-my-risk/ ...Read more
Measures a protein: The ca-125 test is a blood test that detects a protein in the blood that is produced by malignant ovarian cells. It is used to help determine if an ovarian cancer patient has had a relapse, or to help differentiate a cyst found by sonogram or ct. The most important point: it should never be used as a yearly screening test, and should not be requested by patients as a screening test. ...Read more
My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?
Yes: Many genes have been identified that may increase your risk of ovarian cancer from the normal <1% risk to a doubling or up to a 40% lifetime risk. The best validated gene is the brca gene. The new next generation sequencing technology can check for 19 genes at once that increase risk of breast, ovarian and uterine cancer. This may be helpful if you have a family history of ovarian cancer. ...Read more
Depends: At 25 years of age, of course it would be very unlikely for you to have cancer. More common than typical ovarian cancer at your age would be sex-cord stromal tumor or germ cell tumors. Markers for these would be: estradiol, testosterone, hcg, afp, ldh. Ca-125 is the tumor marker for the common ovarian cancers that occur with older women. An ultrasound, ct scan or MRI might be ordered as well. ...Read more
My wife has very high estrogen level she did have ovarian cancer which was removed she had blood tests the other day and her estrogen level were 2000?
Talk with your doc: As a gynecologic oncologist, I don't usually follow estrogen as a marker for ovarian cancer. There are a few rare exceptions (granulosa cell tumors). Estrogen is also made in fat cells. You and your wife should have a conversation with her doctor about why they are sending estrogen levels at all. Aromatase inhibitors are a group of drugs that prevent estrogen production and can be used to treat. ...Read more
I completed chemotherapy for ovarian cancer. No cancer was detected in followup tests. Am I still at risk for cancer? #nqlu my chemotherapy started last sept. And ended in early jan. Last nov., I had surgery (hysterectomy). I have since had clean reading
Yes, you are.: You are always at a risk of your cancer returning. The higher your stage, the higher the risk. The goal of chemotherapy is to kill any cells that were not removed by surgery. Hopefully that worked and got every last cancer cell, but ovarian cancer has a nasty tendency to come back. Go here for the statistics: http://seer. Cancer. Gov/statfacts/html/ovary. Html ...Read more
99% when cancer: Ca-125 is 99% accurate if an ovarian cyst or tumor happens to be cancer. The problem with this blood test is that it is very inaccurate when there is no cancer (called a false positive), sometimes up to 45%. This is why ob/gyns do not use this test as a screening test, or at patient request. ...Read more
Other conditions too:
Ca25 test can be positive in many conditions
other malignancies like lung, breast. Pacreas and GI tract
cysts of the ovaries
so here you have it it is not a specific test for ovarian cancer, thogh it may be positive as well. ...Read more
Not very.: Ca 125 is touted as a screening tool for ov ca but is elevated in only 50% of those with early stage disease. Approx 1% of normals have a high ca 125. Since ovarian cancer is relatively uncommon, the ability of a positive test to predict ca is about 3%. There is general consensus that ca 125 is not a good screening tool for average risk females. Consider ca 125 for those with high risk. ...Read more
Hard to tell from...: Your question. Pelvic physical exam may be able to feel abnormal ovaries, but not diagnostic of cancer. Pelvic sono takes sound wave picture of ovaries and can give better picture (especially in overweight or obese women where ovaries can't usually be felt on physical exam). Sono may find suspicious ovaries, direct further testing, e.g. Biopsy. ...Read more
It depends.: Pain and bloating can be signs of ovarian cancer, but they can be just from a painful period. Ovarian cancer would be more likely in older women, like 40+ years, and most likely in women 70+ years. Other tests, like pelvic exam, ca-125, and transvaginal ultrasound would be needed. The ultimate way to know is surgery to see if it is in fact, a tumor of something else. ...Read more
How can I be tested for ovarian cancer? What type of tests do they use to determine if you have ovarian cancer?
Exam, not a CA-125!: A ca-125 test should not be ordered unless there is a diagnosis of ovarian cancer. This test can be elevated in a number of benign conditions. Regular follow up with your gynecologist is the best way. If there is a concern based on symptoms or an exam, your gynecologist may obtain a transvaginal ultrasound. Hope this helps. ...Read more
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