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Doctor insights on: L Dopa

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What condition is l-dopa primarily used to treat?

What condition is l-dopa primarily used to treat?

Parkinson’s disease: Levodopa, or L-dopa, is primarily used to treat Parkinson’s disease, which is a neurological movement disorder and is thought to be caused by low levels of a chemical in the brain (or neurotransmitter) called dopamine. Levodopa serves as the brain’s dopamine replacement ...Read more

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, how long will it take for my dopamine levels to become stable on l dopa?

, how long will it take for my dopamine levels to become stable on l dopa?

L-dopa levels: L-dopa comes in short and long acting forms, which last from two to about eight hours. After starting l-dopa therapy, if the doses are taken very regularly, the brain levels will stabilize after four to six weeks, because of the many interacting brain regions that are affected.. ...Read more

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Does dopa mucuna and l dopa cause people to loss weight because they are getting dopamine back that was blocked by antipsychotics?

Does dopa mucuna and l dopa cause people to loss weight because they are getting dopamine back that was blocked by antipsychotics?

WAY oversimplifying: Weight gain with antipsychotics is poorly understood but probably has nothing to do with dopamine. May be 1 or more other receptor types, including histaminic H1, serotonin 2A & 2C, muscarinic M(3), & adrenergic receptors. (Quiz later.) Receptor neurochemistry is INCREDIBLY complex & subtle & messing around out of ignorance with stuff like mucuna after stopping antipsychotics could be risky. ...Read more

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My 70+ old aunt has been diagnosed with parkinson. Is capsule containing 120mg of l-dopa derived from velvet beans ok to start for parkinson?

My 70+ old aunt has been diagnosed with parkinson. Is capsule containing 120mg of  l-dopa derived from velvet beans ok to start for parkinson?

Why...??: Do you &/or aunt live in nigeria? Is she too poor to afford real drugs? Velvet beans contain lots of substances your aunt shouldn't take. Why do you want your beloved aunt to banana-kick around her dr & use an unprescribed product whose constituents & purity are unregulated? If you don't trust the dr's meds why do you trust the dr's diagnosis? Is this some ayurvedic fancy? Please provide details. ...Read more

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Any ways to prevent shaking taking levodopa (l-dopa) for Parkinson's disease?

Any ways to prevent shaking taking levodopa (l-dopa) for Parkinson's disease?

I think you mean....: I suspect you mean you're on l-dopa, but you're still having tremor. Don't just add more sinemet--instead add Azilect (rasagiline) to boost your natural Dopamine and the Dopamine you get from l-dopa! this helps more fully and consistently suppress tremor, slowness & stiffness! another option would be adding amantidine to l-dopa. This often improves incomplete tremor relief by l-dopa thru glutamate antagonism. ...Read more

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Do you know any ways to prevent vomitting after taking levodopa (l-dopa) for Parkinson's disease?

Do you know any ways to prevent vomitting after taking levodopa (l-dopa) for Parkinson's disease?

See your neurologist: Carbidopa is usually coadministered with levodopa to increase the effective half-life of levodopa. This allows less levodopa to be required, which in turn reduces the nausea/vomiting side effects. Be sure to schedule an appointment with your neurologist in order to review your medications for Parkinson's disease. More information: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a601068.html ...Read more

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Is it dangerous for a relatively healthy person without Parkinson's or schizophrenia to take l-dopa?

Is it dangerous for a relatively healthy person without Parkinson's or schizophrenia to take l-dopa?

Why do you want to ?: Pts with schizophrenia should generally avoid taking L-DOPA unless it is a last-ditch effort to address a movement disorder. It is well known that excessive amounts of dopamine do result in an increased quantity of the neurotoxic metabolites of dopamine which could potentially overwhelm the brains capacity to mange the reactive oxidative species. Please dont experiment! ...Read more

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What Parkinson's treatments are there beyond l-dopa 56 year old male. Has not responded to levadopa.

Multiple medicines: There are numerous treatment options available for parkinson's disease. Other medications include Dopamine agonists (requip, mirapex, neupro), as well as other medications such as azilect (rasagiline). If the Levodopa has not made a difference, a higher dose may still be effective. Talk with your doctor about what sorts of changes you should expect to see from any of these medications. ...Read more

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Can you tell me how l-dopa effect the actions of neurotransmitters at the synapse in Parkinson's patients?

Can you tell me how l-dopa effect the actions of neurotransmitters at the synapse in Parkinson's patients?

Explanation: Although Parkinson's is a multi-neurotransmitter deficiency disorder, the main focus involves a dopamine deficiency within the basal ganglia. L-DOPA is a precursor, which is transformed within the body to dopamine after ingestion, and supplements the deficiency present in the substantia nigra which improves communication with areas such as putamen and globus pallidus. ...Read more

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Is it safe to take n-acetyl l-tyrosine and the supplement l-dopa (mucuna) together to support and boost dopamine production?

Is it safe to take n-acetyl l-tyrosine and the supplement l-dopa (mucuna) together to support and boost dopamine production?

Yes: Yes, it is perfectly safe to take n-acetyl-l-tyrosine and l-dopa together. Adequate sleep, exercise and a healthy diet can also increase Dopamine production. See http://www.Wikihow.Com/increase-dopamine and http://www.Peaktestosterone.Com/natural_dopamine_increasers.Aspx for more info. ...Read more

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I want to boost dopamine level .So what's the difference among the three supplement : L Tyrosine , L-Dopa (Mucuna) and L-Phenylalanine?

I want to boost dopamine level .So what's the difference among the three supplement : L Tyrosine , L-Dopa (Mucuna) and  L-Phenylalanine?

Amino acids: These are different amino acids your body can use to make other amino acids. Most people want to boost their dopamine level in the brain, it is not clear that taking supplements can do this. What is you goal, actually? It would be better to start there. ...Read more

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What can you do if taking levodopa (l-dopa) for Parkinson's disease causes nausea and vomiting?

What can you do if taking levodopa (l-dopa) for Parkinson's disease causes nausea and vomiting?

Comments: 1. You are rather young at age 34 to have developed Parkinson's disease. Do you perhaps have a different diagnosis to explain your symptoms? 2. L-DOPA could cause GI side effects, and other meds may be tolerated better, BUT, 3. I recommend a second opinion from a neurologist who specializes in movement disorders at Univ of Pittsburgh. ...Read more

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Will Abilify (aripiprazole) take away some if the muscular rigidity gotten from other ssri medications now stopped bc it is a partial dopa/sero antagonist?

Will Abilify (aripiprazole) take away some if the muscular rigidity gotten from other ssri medications now stopped bc it is a partial dopa/sero antagonist?

I am not sure the: Ssri has caused muscular rigitity. It likely hasn't helped much, with your level of tissue problems. Consider an snri, like cymbalta, which helps pain and mood. Abilify (aripiprazole) will not cure muscular rigitity. It's mechanism is unlikely to cause more but it could. Do you sleep poorly at night or grind your teeth? If so, needs management. Sleep key to muscular health, Clonazepam 1 mg at bed may help. ...Read more

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I have been on sinemet (carbidopa and levodopa) for years for dopa responsive dystonia. It has resolved all my symptoms. I am 60 yr old and I am considering botux injections for wrinkles. Would the botux affect my drd?

I have been on sinemet (carbidopa and levodopa) for years for dopa responsive dystonia. It has resolved all my symptoms. I am 60 yr old and I am considering botux injections for wrinkles. Would the botux affect my drd?

Depends: It really depends on the location of your dystonia. In fact, Botox is a treatment for localized dystonia...Since you are considering cosmetic use only, then it really should not be a problem. Need to discuss this with your physician. ...Read more

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In her 90s mgm had some shaking and difficulty walking. Very old gp gave her dopa without diagnosis. She never had Parkinson's but med side effects. Y?

In her 90s mgm had some shaking and difficulty walking. Very old gp gave her dopa without diagnosis. She never had Parkinson's but med side effects. Y?

Depends: It is not uncommon to try and treat tremors in the elderly with parkinson disease meds. Parkinson's is a very complex disorder with a variety of subtypes and the book is constantly being rewritten. Essentialy tremor is best treated with beta blockers usually, but in an elderly person a trial of Dopamine agonists might be tried, then stopped if side effects or other issues develop. ...Read more