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Doctor insights on: Kidney Disease Not Multiple Myeloma Severe Itch

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Dr. Ana Adelstein
118 doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


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My brother (51) is in the final stages of multiple myeloma and was told he will die of kidney failure. Blood tranfusions weekly. Timeline estimate?

My brother (51) is in the final stages of multiple myeloma and was told he will die of  kidney failure. Blood tranfusions weekly. Timeline estimate?

Get extra support: Agree with prior answer that difficult to say. If not already involved ask for a palliative medicine specialist to work with your hematology-oncology team. They might be able to provide additional prognostication opinions as they monitor his progress and also provide additional support for the time that he has. ...Read more

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How does multiple myeloma affect the kidney?

How does multiple myeloma affect the kidney?

Nephropathy: Myeloma produces proteins called light chains which can essentially "clog up" the kidney producing myeloma nephropathy. Myeloma also produces humoral substances which can damage the kidney. ...Read more

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Kidney biopsy shows the reason for kidney failure is multiple myeloma. No bone damage, hemo. More than 12. Will kimo therapy help to recover fully?

Seek opinion from a: This is unusual way to make a diagnosis of multiple myeloma(mm). Typically we need to do a bone marrow biopsy and look for cancer cells in the marrow. These cells produce abnormal proteins(m protein) which will show up either in the blood(commonly) or in the urine. We use a test called protein electrophoresis. If these tests have not been done, seek a second opinion. Chemo will help to control mm. ...Read more

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Do you think that multiple myeloma could cause heart disease?

It is possible: Some forms of myeloma secrete a protein called a light chain that can invade organs like the heard or liver and cause it to function poorly. Most of the problems with the heart arise from many of the early treatments of myeloma which included a drug called adriomycin. Modern chemotherapy can still cause heart problems but not at the same rate. ...Read more

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Has anyone suffering from multiple myeloma been pregnant while living with this disease?

Yes: We evaluated this recently for a patient & there have been about a dozen case reports with women diagnosed during pregnancy and also getting pregnant & delivering safely after diagnosis. Definitely rare & hi risk necessitating long discussions with hematologist & ob. ...Read more

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What's the reason for fever with low hemoglobin for 79 yrs old male with multiple myeloma if disease is under control after a year of velcade&melfalan?

What's the reason for fever with low hemoglobin for 79 yrs old male with multiple myeloma if disease is under control after a year of velcade&melfalan?

Myeloma, treatment: 1) fever - may be from infection with risk from myeloma itself and therapy. Bortezomib (velcade) can increase risk of herpes zoster (shingles). 2) anemia (low hemoglobin) can be from mulitple myeloma and/or the therapies uesd to control it. Check in with your physician. If confusing a repeat bone marrow biopys and other tests may be needed. ...Read more

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Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Cancer: multiple myeloma is a malignacy of the plasma cells of the marrow. It presents with bone pain and lytic lesions usually diffusely invoving the spine. It is very effectivey treated with newer chemotherapeutic agents. p ...Read more

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What's it mean if on whole body X-ray there is no defects except spondylitis? Now has severe pain on hip and leg muscles. Can it be multiple myeloma?

MM = lytic bone: In multiple myeloma (MM) the classical bone lesions are lytic -- "moth eaten" appearance on x-ray. There are other patterns in the bone found on MRI in MM patients. However, you can have MM without obvious bone lesions. And, musculoskeletal pain can come from many, many causes including non-cancerous causes, so see your physician and possibily physical therapists for help in diagnosing & treating. ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


Dr. Tarek Naguib
2,382 doctors shared insights

Kidney Diseases (Definition)

Kidney diseases include hereditary problems such as polycystic kidney disease, structural abnormalities, infections, cancer, and damage to kidneys due to other medical conditions ...Read more