Top
40
Doctor insights on: Kidney Disease Not Multiple Myeloma Severe Itch

Share
1

1
What specific blood/urinalysis levels are significant to kidney problems of diagnosis but untreated lupus patient. Symptoms? Failure or disease? Difference?

What specific blood/urinalysis levels are significant to kidney problems of diagnosis but untreated lupus patient. Symptoms?  Failure or disease? Difference?

See answer : Blood tests for bun, creatinine, and GFR are used to determine if you have chronic kidney disease (ckd) and what stage (1 thru 5) based on GFR result. Urinalysis helpful to detect microscopic blood and protein both of which are common with kidney disease with degree of each related to type and severity of kidney disease. If significant protein (>1+), then 24-hr urine collection done to quantitate. ...Read more

Dr. Erik Borncamp
128 doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


2

2
Are there serious dangerous STDs other than HIV, hepatitis and pelvic inflammatory disease ? What can they cause in critical cases?

Are there serious dangerous STDs other than HIV, hepatitis and
 pelvic inflammatory disease ? 
What can they cause in critical cases?

Yes: Syphilis and gonorrhea are dangerous if left untreated with bad complications, and other STDs too, but we don't here much about those complications now given the widespread availability of medications and easy treatment once diagnosed, the problem is undiagnosed cases, partial treatment or treating only one partner not the other partner(s) ...Read more

3

3
What is chronic microvascular ischemic disease, chronic migraine, and a disseminating process such as multiple sclerosis mean on MRI? Do I have MS?

What is chronic microvascular ischemic disease, chronic migraine, and a disseminating process such as multiple sclerosis mean on MRI? Do I have MS?

You're the patient..: ...not the MRI. Presumably you didn't just wander into an MRI facility & make an impulse purchase. The MRI was ordered by your doctor & for a reason. The radiologist isn't paid to diagnose YOU; (s)he just looks at studies & reports what (s)he sees. Go back to the ordering MD; diagnosing YOU is his/her job. Ask to see the MRI: in radiology, 1 picture is worth 1000 words. ...Read more

4

4
What causes a kidney disease flare in SLE ?

What causes a kidney disease flare in SLE ?

See details: You are asking the same question over and over. You need a better understanding of your disease and should discuss these issues with your doctor. ...Read more

5

5
Could psoriasis attack other organs like kidney and liver ?

Could psoriasis attack other organs like kidney and liver ?

Beyond the skin: Psoriasis is associated with 5 different types of arthritis, an increased risk of cardiovascular disease and diabetes. Other comorbidities associated with psoriasis include cancer, obesity, metabolic syndrome and other immune-related conditions such as Crohn's disease ...Read more

Dr. Jay Park Dr. Park
3 doctors agreed:
6

6
Why does anemia cause progression of chronic kidney disease?

Dr. Jay Park Dr. Park
3 doctors agreed:
Why does anemia cause progression of chronic kidney disease?

Reversed sequence: Progression of chronic kidney disease results in development of anemia because kidney is no longer able to produce erythropoietin, a hormone enhancing red blood cell production from bone marrow. ...Read more

See 1 more doctor answer
8

8
Are all nsaids drugs forbidden when kidneys are damaged with chronic kidney disease, meaning that only corticoid might be given against inflammatory ?

Are all nsaids drugs forbidden when kidneys are damaged with chronic kidney disease, meaning that only corticoid might be given against inflammatory ?

It depends: I see that you have both polycystic kidney disease and an enthesopathy, the latter being an illness for which the nsaids are extremely valuable. I have little use for "cookbook medicine" ("people with ___ can't take ___"). Your physician will explain the risks and benefits (relief from pain, you must stay well-hydrated) to using nsaids in our situation. ...Read more

9

9
Graves disease, psoriasis, arthritis. Certain have anemia of chronic disease. Vitamin/mineral levels including iron are ok. What can I do about it?

Graves disease, psoriasis, arthritis. Certain have anemia of chronic disease. Vitamin/mineral levels including iron are ok. What can I do about it?

Association: Autoimmune diseases can affect almost any part of the body, including the heart, brain, nerves, muscles, skin, eyes, joints, lungs, kidneys, glands, the digestive tract, and blood vessels.Hyperthyroidism and psoriatic arthritis can occur together. Have your physician try to get these autoimmune diseases under control. Subclinical hypothroidism associated with 25% of patients with psoriasis. ...Read more

10

10
Severe kidney pain, diarrhea, no fever. Doctor or er? Kidney infection, stones or inflammation? I also have behcets disease.

Severe kidney pain, diarrhea, no fever. Doctor or er? Kidney infection, stones or inflammation? I also have behcets disease.

Clinic visit would: Be fine. Your dr may consider doing some blood and urine tests. Take care! http://www.mayoclinic.com/health/kidney-pain/my00125. http://www.mayoclinic.com/health/behcets-disease/ds00822/dsection=treatments-and-drugs. http://www.m.webmd.com/a-to-z-guides/digestive-diseases-diarrhea. ...Read more

See 1 more doctor answer
12

12
Can people infected with severe oesophagitis and chronic kidney disease (ckd) die?

Can people infected with severe oesophagitis and chronic kidney disease (ckd) die?

Yes, but how soon : Depends on the cause of these diseases. Oesophagitis due to disseminated herpes infection in a person with late stage kidney failure would be a bad sign. ...Read more

13

13
Might having kidney problems, or chronic kidney disease, lead to some form of rheumatoid arthritis?

Might having kidney problems, or chronic kidney disease, lead to some form of rheumatoid arthritis?

No !: Having kidney problems or chronic kidney disease will not lead to rheumatoid arthrtis . Rheumatoid arthritis is an autoimmune inflammatory disease with it s own patho physiology and is not secondary toi kidney disease. ...Read more

14

14
Could many itching spots on the back (extant for several years) be caused by the patient having polycystic kidney disease (ckd stage 3a)?

Could many itching spots on the back (extant for several years) be caused by the patient having polycystic kidney disease (ckd stage 3a)?

Not likely,,,: Polycystic kidney disease is characterized by flank pain, hematuria (blood in urine), urinary tract infection in 30s and 40s, and hypertension. Also cysts in the kidney and liver as well as berry aneurysms in the brain are characteristic. There are apparent no skin lesions that characterize this disease, unless they're due to whatever causes the urinary tract infections. Hope this helps. ...Read more

See 1 more doctor answer
16

16
Do you think that multiple myeloma could cause heart disease?

Do you think that multiple myeloma could cause heart disease?

It is possible: Some forms of myeloma secrete a protein called a light chain that can invade organs like the heard or liver and cause it to function poorly. Most of the problems with the heart arise from many of the early treatments of myeloma which included a drug called adriomycin. Modern chemotherapy can still cause heart problems but not at the same rate. ...Read more

See 1 more doctor answer
17

17
I have rheumatic heart disease and some venous insufficiency; are there single drugs that treat both?

I have rheumatic heart disease and some venous insufficiency; are there single drugs that treat both?

2:1 Drug Rx: These are two different disease processes. Venous insufficiency is treated most often without medication but with compression. With your ra, you may feel uncomfortable with the compression that may require some compromise (a palliative approach) between yourself and your clinician. ...Read more

18

18
Splenic cyst, 16-17cm, no other symptoms, extensive bloodwork, no parasitic infection, no malignancy, can't conclude if hydatid or of what kind. ?

Splenic cyst, 16-17cm, no other symptoms, extensive bloodwork, no parasitic infection, no malignancy, can't conclude if hydatid or of what kind. ?

Leave it alone: Benign cysts like this are uncommon, mysterious, and a non-problem. They're probably little developmental things, like dimples only involving the spleen, and that grow over time. If you're confident that you don't have echinococcus (travel history is key), forget about it. ...Read more

19

19
What is reactive leukocytosis? Among many other illnesses, I have severe copd(was on hospice for 3mo.) CHF & CKD stage 3 if this helps in any way.

What is reactive leukocytosis? Among many other illnesses, I have severe copd(was on hospice for 3mo.) CHF &  CKD stage 3 if this helps in any way.

Normal immune response: Reactive leukocytosis means you have more white blood cells then normal, and it's due to a reaction to an illness. It's not due to leukemia. Since you have COPD, you are probably taking prednisone. This is one of the main causes of reactive leukocytosis. Other causes include stress, infection, and inflammation. ...Read more

20

20
Failure kidney transplant because recurrence of focal glomerulosclerosis also has global hypokinesia on dialysis no diabetics or heart disease . ?

Failure kidney transplant because recurrence of focal glomerulosclerosis also has global hypokinesia on dialysis no diabetics or heart disease . ?

Transplant: Focal segmental glomerulosclerosis or fsgs has recurrence rate of 10 % after transplant. You can get another transplant and decrease rate of recurrence by getting plasmapheresis and galactose therapy before next surgery. These therapies have been shown to reduce risk in selected group of patients. ...Read more

21

21
Which groups are most frequently affected by multiple myeloma?

Which groups are most frequently affected by multiple myeloma?

Blacks in US: Twice the incidence in african americans than caucasians. Some families have a higher incidence. ...Read more

See 1 more doctor answer
23

23
My brother (51) is in the final stages of multiple myeloma and was told he will die of kidney failure. Blood tranfusions weekly. Timeline estimate?

My brother (51) is in the final stages of multiple myeloma and was told he will die of  kidney failure. Blood tranfusions weekly. Timeline estimate?

Get extra support: Agree with prior answer that difficult to say. If not already involved ask for a palliative medicine specialist to work with your hematology-oncology team. They might be able to provide additional prognostication opinions as they monitor his progress and also provide additional support for the time that he has. ...Read more

See 1 more doctor answer
24

24
How does multiple myeloma affect the kidney?

How does multiple myeloma affect the kidney?

Nephropathy: Myeloma produces proteins called light chains which can essentially "clog up" the kidney producing myeloma nephropathy. Myeloma also produces humoral substances which can damage the kidney. ...Read more

See 1 more doctor answer
25

25
Kidney biopsy shows the reason for kidney failure is multiple myeloma. No bone damage, hemo. More than 12. Will kimo therapy help to recover fully?

Seek opinion from a: This is unusual way to make a diagnosis of multiple myeloma(mm). Typically we need to do a bone marrow biopsy and look for cancer cells in the marrow. These cells produce abnormal proteins(m protein) which will show up either in the blood(commonly) or in the urine. We use a test called protein electrophoresis. If these tests have not been done, seek a second opinion. Chemo will help to control mm. ...Read more

26

26
Do you think that multiple myeloma could cause heart disease?

It is possible: Some forms of myeloma secrete a protein called a light chain that can invade organs like the heard or liver and cause it to function poorly. Most of the problems with the heart arise from many of the early treatments of myeloma which included a drug called adriomycin. Modern chemotherapy can still cause heart problems but not at the same rate. ...Read more

See 1 more doctor answer
27

27
Has anyone suffering from multiple myeloma been pregnant while living with this disease?

Yes: We evaluated this recently for a patient & there have been about a dozen case reports with women diagnosed during pregnancy and also getting pregnant & delivering safely after diagnosis. Definitely rare & hi risk necessitating long discussions with hematologist & ob. ...Read more

See 1 more doctor answer
28

28
What's the reason for fever with low hemoglobin for 79 yrs old male with multiple myeloma if disease is under control after a year of velcade&melfalan?

What's the reason for fever with low hemoglobin for 79 yrs old male with multiple myeloma if disease is under control after a year of velcade&melfalan?

Myeloma, treatment: 1) fever - may be from infection with risk from myeloma itself and therapy. Bortezomib (velcade) can increase risk of herpes zoster (shingles). 2) anemia (low hemoglobin) can be from mulitple myeloma and/or the therapies uesd to control it. Check in with your physician. If confusing a repeat bone marrow biopys and other tests may be needed. ...Read more

See 1 more doctor answer
29

29
Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Cancer: multiple myeloma is a malignacy of the plasma cells of the marrow. It presents with bone pain and lytic lesions usually diffusely invoving the spine. It is very effectivey treated with newer chemotherapeutic agents. p ...Read more

30

30
What's it mean if on whole body X-ray there is no defects except spondylitis? Now has severe pain on hip and leg muscles. Can it be multiple myeloma?

MM = lytic bone: In multiple myeloma (MM) the classical bone lesions are lytic -- "moth eaten" appearance on x-ray. There are other patterns in the bone found on MRI in MM patients. However, you can have MM without obvious bone lesions. And, musculoskeletal pain can come from many, many causes including non-cancerous causes, so see your physician and possibily physical therapists for help in diagnosing & treating. ...Read more

31

31
Why sickle cell anemeia / multiple myeloma cause diabetes insipidus ? Is it because it may obstruct the blood flow to the kidneys and damage them?

Why sickle cell anemeia / multiple myeloma cause diabetes insipidus ? Is it because it may obstruct the blood flow to the kidneys and damage them?

Basically right: Even sickle cell trait ruins much of the concentrating ability of the kidneys by adulthood. Myeloma is more likely to damage and obstruct the tubules themselves. Both produce a kidney lesion that prevents the urine from becoming concentrated, rather than a pituitary diabetes insipidus. ...Read more

32

32
I have Multiple Myeloma & I'm hypocellular I have been offered steroid injection for pain is it safe?

I have Multiple Myeloma & I'm hypocellular I have been offered steroid injection for pain is it safe?

Steroid is treatment: Steroids are part of the standard treatment of myeloma. Usually the steroid (typically dexamethasone) is administered with another agent. It is usually administered by mouth. It's not clear what your pain is or what kind of injection is proposed. ...Read more

See 1 more doctor answer
33

33
M54, if m protein is high, no mark on x ray, blood count normal. Does this means no multiple myeloma.

It depends on severa: Besides m protein level, a bone marrow eaxmination is required to determine the plasma cell number/count. If the bone marrow does not have more than 10% plasma cells, then it is not a myeloma, which usually has lots of plasma cells in the bone marrow. ...Read more

34

34
I'm suffering from seizures after stopping thalidomide. I've used other to stop them but they won't go away. A Multiple Myeloma patient ?

I'm suffering from seizures after stopping thalidomide. I've used other to stop them but they won't go away. A Multiple Myeloma patient 
?

? Relationship.: Thalidomide has neurological side effects but is not commonly thought to cause seizures. In fact, early studies suggested thalidomide might have anti-seizure activity. Myeloma does not commonly cause seizures either, although it might contribute to seizures if it causes electrolyte abnormalities or a skull tumor involves the surface of the brain. Work with your doc to evaluate and treat seizure ...Read more

35

35
Is there a potential link between an elevated d-dimer level and a diagnosis of multiple myeloma? Note: I have an oncologist, just doing some extra research.

Potentially: As both multiple myeloma and several of the therapies utilized in this condition lead to increased risk of clots, and d dimer elevation is supportive of a clotting process. ...Read more

36

36
What is a young age for multiple myeloma? Under 50 years?

MM and age: Mm is a disease of older adults. The median age at diagnosis is 66 years; only 10% and 2% of patients are younger than 50 and 40 years, respectively. ...Read more

See 1 more doctor answer
38

38
What drugs are the standard of care in the us for multiple myeloma? What drugs are the standard of care in france, germany and canada? Why differe

Complex: Too complex to answer definitively in 400 characters. 1) country differences depends on different forms of "fda" & often cost/value calculations in other countries. 2) "standard" is really standards (plural) of care, which depends on untreated/relapsed, bmt candidate (possibly), & individual considerations (eg renal fn, oral vs. Iv, age, lifestyle, etc). This complexity reflects rapid change. ...Read more

39

39
How long do patients live with multiple myeloma?

How long do patients live with multiple myeloma?

Depends: Myeloma has a variable natural history. Many patients have had myeloma for years prior to diagnosis without realizing it, while others are diagnosed by screening for monoclonal protein in the blood. Modern hematologists can use advanced treatments like velcade, revlimid, (lenalidomide) thalomid, and stem cell transplant, allowing myeloma patients to live longer than ever. More info: http://bit.Ly/lrzotm. ...Read more

See 1 more doctor answer
40

40
What do you suggest if my dad was just diagnosed with multiple myeloma?

Treatment helps: The majority of people with myeloma have a significant benefit from treatment. He should see an oncologist, of course. Learn more about it here: http://www.cancer.gov/cancertopics/pdq/treatment/myeloma/Patient ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


Previous Kidney Disease (Definition)

Polycystic kidney disease is a kidney disorder passed down through families in which multiple cysts form on the kidneys, causing ...Read more