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Doctor insights on: Keratinizing Squamous Cell Carcinoma

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What is the mean of keratinizing squamous cell carcinoma tonguetongue. And what type of cancer is?

What is the mean of keratinizing squamous cell carcinoma tonguetongue. And what type of cancer is?

Its cancer of the To: This report indicates the diagnosis of Cancer of the tongue. Keratinizing squamous cell is a type of cell that cover the tongue and our skin all over the body. This person likely has been told that he/she has Cancer of the mouth (Tongue) ...Read more

Dr. Barry Rosen
4,344 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, I've used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Hi, my father has cancer and reports says as keratinizing squamous cell carcinoma, grade 2. Is it curable? Please explain.

Hi, my father has cancer and reports says as keratinizing squamous cell carcinoma, grade 2. Is it curable? Please explain.

Probably: I assume this is a skin cancer since it's keratinizing and if that's the case, it's highly curable. However, if it's squamous cell carcinoma of another organ, you need to tell us what organ before we can tell you how likely a cure might be. ...Read more

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Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?

Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?

Needs treatment: Means you have cancer of oral cavity (buccal mucosa) from your description appear to be localised you will have good prognosis needs further work up for staging &care, by surgical excision for localized small area, or chemo radiation, discuss with your physicians and please do not delay. Good luck. ...Read more

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Father just diagnosed with Differentiated Keratinized Squamous Cell Carcinoma in his prostate. Can you explain what this is, treatment & expectancy?

Father just diagnosed with Differentiated Keratinized Squamous Cell Carcinoma in his prostate. Can you explain what this is, treatment & expectancy?

An uncommon problem.: Squamous cell carcinoma (SCC) is a very rare form of prostate cancer, less than 1%. Because it is so rare, I recommend having the pathology reviewed at a specialized lab such as at Johns Hopkins or the Mayo clinic. If it is confirmed as SCC, treatment can vary, from surgery, to radiation, to chemotherapy. I'd seek help from a center that specializes in prostate cancer. ...Read more

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What is the squamous cell carcinoma keratinizing meaning? And is that danger or not?

What is the squamous cell carcinoma keratinizing meaning? And is that danger or not?

Squamous cell: Depends on the location. On the skin, a squamous cell carcinoma is usually easily treated by excision. A squamous cell of the lung or of the head and neck is a totally different animal and very very serious. ...Read more

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What is squamous cell carcinoma like?

What is squamous cell carcinoma like?

Depends on site: Squamous cell carcinomas of the skin are usually slow growing and metastasize only infrequently. Squamous cell carcinomas of the lung are lethal and a majority of the patients are dead within a year. Squamous cell carcinomas of the esophagus, cervix, oro-pharynx etc fall in between. ...Read more

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What is vasive squamous cell carcinoma?

What is vasive squamous cell carcinoma?

"Invasive" - deeper: Skin squamous cell carcinoma (scc) often goes through stages of evolution on its way to becoming "invasive" and eventually metastasizing. It may begin as an area of sun damage or pre-cancer (actinic keratosis) and worsen to become a superficial scc that does not yet invade deeper (scc in situ). Eventually, the scc will start to go deeper and become "invasive", then metastasize if left unchecked. ...Read more

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Can you explain squamous cell carcinoma?

Can you explain squamous cell carcinoma?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

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Can children get squamous cell carcinoma?

Can children get squamous cell carcinoma?

Very rarely: Squamous cell carcinomas are uncommon in children. When diagnosed in young individuals, there is usually a predisposing factor like immunosuppression (transplant patients), previous exposure to radiation or chemotherapy, or human papilloma virus infection. Squamous cell cancers of the skin usually takes years of ultraviolet light exposure before appearing at an average age of 65. ...Read more

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What are stages of squamous cell carcinoma?

What are stages of squamous cell carcinoma?

Differentiated: The pathology report will desribe well, moderate or poorly differentiated. Well differentiated is less advanced. It will also describe depth on invasion and whether nerves are involved. An evaluation of lymph nodes is done to confirm squamous cell is localized to skin. In advanced cases it will have spread requiring surgery followed by radiation, and possible chemotherapy. ...Read more

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What does squamous cell carcinoma mean to you?

What does squamous cell carcinoma mean to you?

Subtype of cancer: It only means-a subtype of cancer. Nothing much. The treatment, prognosis etc- will depend on where is this cancer located primarily? , what is the stage (how big it is? Any lymph node or adjacent tissue involvement? Any spreading to distant organ? Etc.
If you smoke tobacco and drink alcohol- you need to quit. Please discuss in detail with your oncologist. ...Read more

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Does invasive squamous cell carcinoma spread quickly?

Does invasive squamous cell carcinoma spread quickly?

Depends: Origin of cancer is very important. If skin, usually not unless large, ulcerated lesion. Depending on site, stage at presentation then plays a role. Squamous cancers can origin wherever there is skin lining with then resultant pattern of spread so tough to say more. ...Read more

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How do a squamous cell and squamous cell carcinoma differ?

How do a squamous cell and squamous cell carcinoma differ?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

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Is a squamous cell something that forms squamous cell carcinoma?

Is a squamous cell something that forms squamous cell carcinoma?

Not necessarily: Squamous cells are normal constituents of skin and some of the other linings, e.g., vagina. Squamous cells per se do not give rise to any cancer. Some cancer have squamous cell features. ...Read more

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Where can I find squamous cell carcinoma statistics for incidence by age. Looked all over Google and can not locate.?

Where can I find squamous cell carcinoma statistics for incidence by age. Looked all over Google and can not locate.?

Won't find them: You already know that everything depends on location, grade, stage, and a few markers depending on the tumor type. Survival curves are age-adjusted. Age has basically no impact on cancer survivability in adults. A squamous skin cancer is very unlikely to kill. A stage IV squamous lung cancer is lethal regardless of age. Hope things go well for you. Best wishes. ...Read more

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Is stage 3 squamous cell carcinoma very serious?

Is stage 3 squamous cell carcinoma very serious?

Yes: Every case needs to addressed individually as to site, lymph node or organ involvement. Once removed, an oncologist will help plan a treatment course. ...Read more

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What characterizes early stage squamous cell carcinoma?

What characterizes early stage squamous cell carcinoma?

Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more

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Can squamous cell carcinoma spread more quickly after biopsy?

Can squamous cell carcinoma spread more quickly after biopsy?

No: In order to spread the MMP enzyme which theoretically allows more easy entrance of the tumor cells into the blood stream in actuality breaks the connecting cell bonds via e-cadherin into small -s- ecadherin. This interacts with BRACA and other genes to cause rapid metastasis. ...Read more

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Can basal or squamous cell carcinoma be as small as 1mm wide?

Can basal or squamous cell carcinoma be as small as 1mm wide?

Yes: All cancers start as one cell being malignant and all cancers go through a stage where the lesion is 1.0 mm wide.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Drink enough water daily so that your urine is mostly colorless.
Practice safe sex. ...Read more

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How can I tell if squamous cell carcinoma is life threatening?

Can be: Squamous cell cancer in advanced untreated forms can be life threatening. It can be locally aggressive by invading critical structures and can also rarely metastasize to distant organs. Some scc like head and neck locations have a high rate of lymph node spread. Purely skin scc is less dangerous overall than melanoma but still requires timely treatment. ...Read more

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Anyone survive long with squamous cell carcinoma of the epiglottis?

Anyone survive long with squamous cell carcinoma of the epiglottis?

Yes: Unless there is distant metastatic disease, squamous cell carcinoma of the epiglottis is considered curable. Treatment options include surgery, radiation, chemotherapy, or a combination of several. This too will depend on the staging specifics of the disease. ...Read more

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Does stage 3 squamous cell carcinoma affect men different than women?

Does stage 3 squamous cell carcinoma affect men different than women?

Which part of body?: It all depends on where in the body. Squamous cell carcinoma can occur on the skin, lungs, rectum, etc. ...Read more

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What would the life expectancy if diagnosed with squamous cell carcinoma be?

What would the life expectancy if diagnosed with squamous cell carcinoma be?

Of what?: You can have squamous cell of the skin which is almost always curable, of the cervix which is also very curable if found early, or of the lung or esophagus which are bad dudes. ...Read more

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Is poorly differentiated squamous cell carcinoma something that can be cured?

Is poorly differentiated squamous cell carcinoma something that can be cured?

Yes: Squamous cell Ca is a malignancy of tissues arising cutaneously (skin) and abutting internal structures such as bronchus and vagina/ cervix. High grade malignancies arising from such structures such as Ca of skin, bronchogenic Ca and cervix cancer can be cured iif not in metastatic phase, by wide resection, followed by RT - chemo when needed ...Read more

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How to differentiate between the stages of squamous cell carcinoma under the microscope?

How to differentiate between the stages of squamous cell carcinoma under the microscope?

Cant stage: When one examines a biopsy under the microscope, the pathologist will grade the tumor into high and low grade lesions depending on loss of characteristic structure of the normal cell.
Stage depends on clinical evaluation in terms of size and spread from the primary site. ...Read more

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How much chances of getting cured in squamous cell carcinoma of neck which is in T3N1M0 stage?

Discuss fully w/ Dr.: The good news is that it's not spread to other organs, but your jaw bone and nearby lymph node are involved - it's at Stage III and that is not minimal. But your doctor is the best to provide detailed prognosis based on treatment progress and response. Make sure you and a buddy understand the info and get all you need to plan Tx. Follow suggestions, get support and be hopeful. ...Read more

Dr. John Ebner
146 Doctors shared insights

Squamous Cell Cancer (Definition)

By definition, these mimic the squamous epithelial surfaces of the body that provide protection. Keratin pearls, prominent desmosomes, apoptosis of individual cells, staining for the distinctive molecules in these surfaces all help ...Read more


Squamous Cell (Definition)

Describes the tile like architecture of cells; however, their behavior is deranged, nuclei irregualrly enlarged and ...Read more