Doctor insights on:
Keratinizing Squamous Cell Carcinoma
What is the mean of keratinizing squamous cell carcinoma tonguetongue. And what type of cancer is?
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, I've used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Hi, my father has cancer and reports says as keratinizing squamous cell carcinoma, grade 2. Is it curable? Please explain.
Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?
Needs treatment: Means you have cancer of oral cavity (buccal mucosa) from your description appear to be localised you will have good prognosis needs further work up for staging &care, by surgical excision for localized small area, or chemo radiation, discuss with your physicians and please do not delay. Good luck. ...Read more
Father65, biopsy result of nasal polyps- Moderately differentiated infiltrating keratinizing squamous cell carcinoma with areas vasaloid. Is it cancer?
YES!: Follow all work-up and treatment regimens from his pcp, and specialists. ...Read more
Father just diagnosed with Differentiated Keratinized Squamous Cell Carcinoma in his prostate. Can you explain what this is, treatment & expectancy?
An uncommon problem.: Squamous cell carcinoma (SCC) is a very rare form of prostate cancer, less than 1%. Because it is so rare, I recommend having the pathology reviewed at a specialized lab such as at Johns Hopkins or the Mayo clinic. If it is confirmed as SCC, treatment can vary, from surgery, to radiation, to chemotherapy. I'd seek help from a center that specializes in prostate cancer. ...Read more
Depends on site: Squamous cell carcinomas of the skin are usually slow growing and metastasize only infrequently. Squamous cell carcinomas of the lung are lethal and a majority of the patients are dead within a year. Squamous cell carcinomas of the esophagus, cervix, oro-pharynx etc fall in between. ...Read more
"Invasive" - deeper: Skin squamous cell carcinoma (scc) often goes through stages of evolution on its way to becoming "invasive" and eventually metastasizing. It may begin as an area of sun damage or pre-cancer (actinic keratosis) and worsen to become a superficial scc that does not yet invade deeper (scc in situ). Eventually, the scc will start to go deeper and become "invasive", then metastasize if left unchecked. ...Read more
Very rarely: Squamous cell carcinomas are uncommon in children. When diagnosed in young individuals, there is usually a predisposing factor like immunosuppression (transplant patients), previous exposure to radiation or chemotherapy, or human papilloma virus infection. Squamous cell cancers of the skin usually takes years of ultraviolet light exposure before appearing at an average age of 65. ...Read more
Differentiated: The pathology report will desribe well, moderate or poorly differentiated. Well differentiated is less advanced. It will also describe depth on invasion and whether nerves are involved. An evaluation of lymph nodes is done to confirm squamous cell is localized to skin. In advanced cases it will have spread requiring surgery followed by radiation, and possible chemotherapy. ...Read more
Subtype of cancer:
It only means-a subtype of cancer. Nothing much. The treatment, prognosis etc- will depend on where is this cancer located primarily? , what is the stage (how big it is? Any lymph node or adjacent tissue involvement? Any spreading to distant organ? Etc.
If you smoke tobacco and drink alcohol- you need to quit. Please discuss in detail with your oncologist. ...Read more
Where can I find squamous cell carcinoma statistics for incidence by age. Looked all over Google and can not locate.?
Won't find them: You already know that everything depends on location, grade, stage, and a few markers depending on the tumor type. Survival curves are age-adjusted. Age has basically no impact on cancer survivability in adults. A squamous skin cancer is very unlikely to kill. A stage IV squamous lung cancer is lethal regardless of age. Hope things go well for you. Best wishes. ...Read more
Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more
All cancers start as one cell being malignant and all cancers go through a stage where the lesion is 1.0 mm wide.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Drink enough water daily so that your urine is mostly colorless.
Practice safe sex. ...Read more
Can be: Squamous cell cancer in advanced untreated forms can be life threatening. It can be locally aggressive by invading critical structures and can also rarely metastasize to distant organs. Some scc like head and neck locations have a high rate of lymph node spread. Purely skin scc is less dangerous overall than melanoma but still requires timely treatment. ...Read more
Depends: Depends on where it started and how spread it is. ...Read more
Yes: Squamous cell Ca is a malignancy of tissues arising cutaneously (skin) and abutting internal structures such as bronchus and vagina/ cervix. High grade malignancies arising from such structures such as Ca of skin, bronchogenic Ca and cervix cancer can be cured iif not in metastatic phase, by wide resection, followed by RT - chemo when needed ...Read more
When one examines a biopsy under the microscope, the pathologist will grade the tumor into high and low grade lesions depending on loss of characteristic structure of the normal cell.
Stage depends on clinical evaluation in terms of size and spread from the primary site. ...Read more
Discuss fully w/ Dr.: The good news is that it's not spread to other organs, but your jaw bone and nearby lymph node are involved - it's at Stage III and that is not minimal. But your doctor is the best to provide detailed prognosis based on treatment progress and response. Make sure you and a buddy understand the info and get all you need to plan Tx. Follow suggestions, get support and be hopeful. ...Read more