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Kawasaki Disease Pathophysiology
Kawasaki disease is a childhood illness caused by inflammation of medium sized blood vessels. Symptoms include fever for greater than 5 days, strawberry red tongue, red lips, swollen lymph nodes, and a peeling rash. The most serious complication is caused by inflammation of blood vessels that supply the heart, leading to a weakness in the wall of those blood ...Read more
Inflammatory disease: Kawasaki disease is an incompletely understood disease that has characteristics of an inflammatory vasculitis. The cause is unknown. Presentation and symptoms seem most typical for an infection. Successful treatment depends on timely recognition (first ten days) and administration of immunoglobulin. Late treatment may result in coronary aneurysms which can have serious consequences. ...Read more
Possibly: Since doctors are not sure what exactly causes kawasaki disease, the answer is not known exactly. There are theories about possible infectious causes due to the seasonality of the illness. There are also some possible genetic causes due to a high prevalence in some asian ethnicities especially the japanese. Those genetic factors could be passed to your offspring. ...Read moreSee 1 more doctor answer
Autoimmune disease: Kawasaki is a disease in which the body creates antibodies that fight against our own body. Your brother had high fever for more than 5 days, the doctor couldn't find where the infection was comming from and decided to do blood test; that's where he saw high platelets (a blood component) and made the diagnosis. This disease responds very well to a drug named ivig and then aspirine. ...Read moreSee 1 more doctor answer
No. : Kd is not contagious, but there are environmental factors that may include infections, perhaps viral. Viral infections can of course can be passed from person to person. Therefore, kd occurs in clusters, but no one catches kd directly from another person. ...Read moreSee 2 more doctor answers
No: While we have not yet identified the cause of kd, we do know that kd is not a "genetic" disease. However, it is likely that certain genes confer an increased susceptibility for contracting kd or developing some of its complications. ...Read more
See below: The usual symptoms and signs of kawasaki's disease include fever, reddening of the eyes, cracked and inflamed lips and mucous membranes of the mouth with an inflamed "strawberry" tongue, ulcerative gum disease (gingivitis), swollen lymph nodes in the neck (cervical lymphadenopathy), and a rash that is raised and bright red. The rash appears in a glove-and-sock distribution. ...Read more
KD: Kawasaki disease (kd) is an acute vasculitic (inflammation of blood vessels) syndrome of early childhood. It is characterized by fever for more than 5 days, red skin rash, blood-shot eyes without pus, swelling of hands/feet, red and cracked lips/tongue, enlarged lymph nodes, and irritability. It is potentially serious and requires prompt treatment in the hospital. ...Read moreSee 1 more doctor answer
Yes: Kawasaki's disease is a very serious condition that can cause some serious complications such as a coronary artery aneurysm. These aneurysms can clot causing a heart attack or rupture and both of these can cause death. Your pediatrician should hospitalize your child and treat immediately with ivig (immunoglobulins), and that can decrease the risk of this very serious complication. ...Read more
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