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Doctor insights on: K9 Cushings Disease

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Do I have cushing syndrome or disease---what is the difference?

Do I have cushing syndrome or disease---what is the difference?

Cushing's: Cushing's syndrome is any conditions that cause the adrenal gland to produce too much cortisol. Cushing's disease is a adenoma (tumor) in the pituitary that produces a hormone called acth which causes the adrenal gland to produce too much cortisol. ...Read more

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What is the cause of the hyperpigmentation in people with cushing syndrome and addison's disease?

What is the cause of the hyperpigmentation in people with cushing syndrome and addison's disease?

Pituitary hormone: These people have increased secretion of crh (corticotropin releasing hormone & acth (adrenocorticotropic hormone, also called corticotropin) from the pituitary gland. The cells that secrete acth also secrete melanocyt stimulating hormone (msh). Msh stimulates skin and mucus cells to secrete melanin (dark bronze pigment) which leads to the hyperpigmentation. Thats the full story! ...Read more

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What is Cushing syndrome?

Cushing syndrome: read this: http://en.wikipedia.org/wiki/Cushing%27s_syndrome

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What are signs of cushing syndrome?

There are many: Many patients have multiple signs & symptoms, including (but not limited to): facial plethora, violet colored striae ("stretch marks"), high blood pressure, glucose intolerance, weight gain, facial roundness, weakness, and "central" obesity (i.e., in the truncal area). Acne, decreased libido, & menstrual irregularities are common. Detailed exam & testing are necessary to rule out related conditio. ...Read more

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How does one get cushing syndrome?

Cushing's syndrome: Cushing's syndrome is any condition that cause the adrenal gland to produce too much cortisol. Some common cause of cushing's syndrome include taking too much steroids (prednisone by any route), the presence of a tumor on the adrenal gland that produces too much cortisol, a tumor on the pituitary gland that produces too much acth causing the adrenal to make too much cortisol... ...Read more

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Are cushing syndrome tests accurate?

If done correctly.: Diagnosing cushing syndrome (oversupply of cortisol) is tricky. Cortisol levels go up and down normally, depending on the time of day. Therefore, timing of tests for cushing syndrome is important. The actual laboratory test for cortisol, however, is quite accurate. ...Read more

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What is cushing syndrome and its cure?

Pituitary tumor: A pituitary tumor causes classic cushings syndrome. The tumor releases acth which stimulates the adrenal gland to produce corticosteroid hormones. Cushings syndrome can come about because of steroid hormones being used to treat an underlying condition or rarely from a tumor of the adrenal gland. The cure of the syndrome depends on its cause. ...Read more

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Who is most prone to having cushing syndrome?

Rare disease: Cushing's syndrome is more prevalent in women than in men, but it is a relatively rare disease. The incidence is about 4 cases per million people. An endocrinologist may see a couple new cases per year. ...Read more

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What are different ways to treat cushing syndrome?

See below.: First, find out what's causing the cushing's syndrome. If it's due to overuse of steroids, cut down on the dose. If it's due to a tumor, surgery is the best treatment.Tumor in the pituitary can be removed by neurosurgeons, tumors in the adrenal, pancreas, lung can be removed by surgeons. Radiation therapy is used if surgery is not complete. Last but not least, medications can be used. ...Read more

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Is there more than one good way to treat cushing syndrome?

A few options: The treatment options depend on the cause of the cushing's syndrome. If the cause is due to overuse of steroids, then the treatment is to lower the dose. This is the best case scenario. Other treatment options involve: surgery, radiation therapy, and medications. Coincidentally, the fda just approved a new drug for cushing's syndrome on 2/17/2012. ...Read more

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