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Doctor insights on: Juvenile Rheumatoid Arthritis With Negative Ra Ana

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How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from adult ra?

How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from adult ra?

Autoinflammatory dis: Systemic jia/jra is actually an autoinflammatory disease rather than an autoimmune disease and is more similar to periodic fever syndromes than RA or jra. There's a problem with the innate immune system's triggering and control of inflammation, not a problem with mistakenly recognizing one's own proteins as foreign (like a virus). As such, Anakinra and steroids are most effective long term meds. ...Read more

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Dr. Thomas Namey
2,350 doctors shared insights

Arthritis (Definition)

Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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What can be done about juvenile rheumatoid arthritis?

What can be done about juvenile rheumatoid arthritis?

Get proper treatment: Be sure to see a board certified pediatric rheumatologist.There is no reason to suffer with this disease considering how highly effective the medications now available.General pediatricians and family medicine docs are not familiar or comfortable with using weekly low dose Methotrexate and tnf inhibitors that are needed to control 99% of kids with correctly diagnosed jra. Nsaids are not enough rx. ...Read more

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Why so some children get juvenile rheumatoid arthritis?

Why so some children get juvenile rheumatoid arthritis?

Autoimmune: Jra (also called jia) for juvenille idiopathic arthritis is a disease of unknown etiology. There are many theories for why it happens, many believe there is a virus responsible. The damage to the joints, pain and stiffness is due to an inappropriate immune response which results in the immune system attacking tissues of the host (patient). Rheumatologists can provide appropriate DX and rx. ...Read more

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What can I do to address juvenile rheumatoid arthritis?

What can I do to address juvenile rheumatoid arthritis?

Medication : Pediatric rheumatologists specialize in these issues and can prescribe medications or groups of medications to address the underlying pathology. ...Read more

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What sort of symptoms has a child with juvenile rheumatoid arthritis?

Many Sx!: Joint pain is most common, but high fevers and rash can occur, but usually in less than half. Inflammation of the eye can occur, but much less common. If a child has a hot swollen joint, see a rheumatologist! ...Read more

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Is it okay to have my niece do capoeira if she has juvenile rheumatoid arthritis?

Yes, but see doctor: All exercise is good for preserving joint motion. The danger would be if there were to be strong physical contact with a damaged joint that had lost range of motion. In juvenile rheumatoid arthritis, some joints become immobile and cannot bend normally. Also, the cervical spine should be examined for prior damage and the bone density should be assessed for osteoporosis. Needs doctor clearance. ...Read more

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Is the juvenile rheumatoid arthritis rash itchy?

Usually not: However, some older patients report pruritus (itching). ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


Dr. Patricia Foster
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Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more