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Doctor insights on: Juvenile Polyarteritis Nodosa

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Is polyarteritis nodosa an autoimmune disease?

Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

Dr. Charles Lombard
158 doctors shared insights

Polyarteritis Nodosa (Definition)

A disease that causes arteries to ...Read more


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What causes polyarteritis nodosa?

What causes  polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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Is polyarteritis nodosa always an autoimmune disease?

Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

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What is polyarticular juvenile idiopathic arthritis?

What is polyarticular juvenile idiopathic arthritis?

Rheumatoid arthritis: This is rheumatoid arthritis that start during the pediatric years and involves many joints. It is an autoimmune disorder ...Read more

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What is wegener's granulomatosis vasculitis?

What is wegener's granulomatosis vasculitis?

See details: It is a form of vasculitis effecting medium sized arteries and associated with a positive canca blood test. It usually begins as chronic sinusitis but with time can effect many other organ systems including eyes, heart, kidneys, joints, lungs and the nervous system. There are very effective treatments available. ...Read more

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Juvenile rheumatoid arthritis criteria pls?

Juvenile rheumatoid arthritis criteria pls?

Joint swelling >6wks: Jia/jra - general guide 1. Age of onset <16 yr 2. Arthritis (swelling or excess joint fluid), or 2 or more of these: less than full range of motion, tenderness or pain on motion, & increased warmth in at least 1 joint 3.Above signs (seen by doc)for > 6wks 4.Type seen in first 6 mo: a.Polyarthritis: ≥5 inflamed joints b.Oligoarthritis: 4 or fewer joints c.Systemic -fever, arthritis 5.No other cause. ...Read more

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Can polyarteritis nodosa lead to vasculitic neuropathy?

Can polyarteritis nodosa lead to vasculitic neuropathy?

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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Is takayasu's arthritis curable?

Is takayasu's arthritis curable?

No: Takayasu's arteritis (it's not an arthritis) is a vasculitis, which is inflammation of the vessels. Etiology remains unclear, but the immune system is thought to contribute the most to disease. Immunosuppressive meds help control symptoms, but this disease tends to flare. The more severe and frequently the pt flares, the more worried i get about prognosis and may identify pts who need surgery. ...Read more

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How are polymyalgia rheumatica and giant cell arteritis diagnosed?

How are polymyalgia rheumatica and giant cell arteritis diagnosed?

Overlapping: They are overlapping disorders. They can occur separately or together. Clinical experience of the doctor and elevated erythrocyte sedimentationrate are the most reliable findings. ...Read more

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Is polymyalgia rheumatica considered an autoimmune disease?

PMR : Pmr is an inflammatory disorder that affects proximal muscles of shoulder joint and hip joint due to unknown causes. There is inflammation with elevated ESR and crp. There is mild anemia and effusion of tendons around shoulders on us. Temporal arteritis(ta) is seen in 15% of pmr patients. Pmr occurs in 50% of ta patients. It occurs in genetic predisposition triggered by environmental factors. ...Read more

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Is systemic lupus erythematosus fatal?

Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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How is juvenile rheumatoid arthritis diagnosed?

Clinical criteria: Ra (also called jia) for juvenille idiopathic arthritis is a disease of unknown etiology. There are many theories for why it happens, many believe there is a virus responsible. Pain and stiffness may limit activity. Appropriate treatment can vastly benefit the patient, and a rheumatologist can be your best friend. Labs to rule out other causes are undertaken. Clinical criteria make the diagnosis. ...Read more

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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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What causes juvenile rheumatoid arthritis?

What causes juvenile rheumatoid arthritis?

Autoimmune: Juvenile rheumatoid arthritis occurs when the immune system gets confused and starts attacking the joints instead of fighting intruders like bacteria and viruses. Genetic factors play a role in risk for developing autoimmune diseases. Exposure to certain viruses may play a role as well. ...Read more

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Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Could seronegative juvenile rheumatoid arthritis cause..?

Could seronegative juvenile rheumatoid arthritis cause..?

What?: You did not finish the question, but there are many rheumatologic features and systemic features of juvenile rheumatoid arthritis, now called juvenile idiopathic arthritis, since most juvenile arthritis patients do not have ra! ask again, so i can help. ...Read more

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What is juvenile rheumatoid arthritis?

What is juvenile rheumatoid arthritis?

Immune dysfunction!: Jra (also called jia) for juvenille idiopathic arthritis is a disease of unknown etiology. There are many theories for why it happens, many believe there is a virus responsible. The damage to the joints, pain and stiffness is due to an inappropriate immune response which results in the immune system attacking tissues of the host (patient). Rheumatologists can provide appropriate DX and rx. ...Read more

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I want to know my options for treating polyarteritis nodosa?

I want to know my options for treating polyarteritis nodosa?

Limited: Despite many trials, corticosteroids are still the cornerstone of treatment. Cyclophosphamide may be added in more severe cases or in resistant cases of polyarteritis that are not hepatitis b related. Newer agents to treat this condition exist and treatment should only be attempted by a physician intimately familiar with the condition. ...Read more

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What is the definition or description of: Polyarteritis nodosa?

What is the definition or description of: Polyarteritis nodosa?

Polyarteritis nodosa: Polyarteritis nodosa (panarteritis nodosa, periarteritis nodosa or Kussmaul disease) is a disease which causes swelling and inflammation to arteries. ...Read more

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What is inflammatory polyarteritis nodosa? How is it treated?

Inflammation - vesse: It is inflammation of blood vessels, Depending on which blood vessel are involved is where the symptoms and signs are. as the muscle is inflammed, the vessel narrows interferring with the blood flow. This is how polyarteritis causes its problems. The physician will evaluate the patient, get labs and perform imaging to help evaluate for therapy. ...Read more

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If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

Unlikely: This is a very rare disease to have. It most commonly is associated with untreated hepatitis B virus. It can also be idiopathic, meaning, no associated cause is found. With autoimmune diseases in general, there is some inherited component typically, but it does not mean that exact disease will be inherited by another family member or that a family will even develop an autoimmune disease. ...Read more

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What causes polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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What are the tests for polyarteritis nodosa?

Polyarteritis nodosa: Diagnosis made by clinical suspicion based on patient symptoms and findings .Lab findings may include elevated wbc, ESR , CRP and in some patients positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied. ...Read more

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What are the symptoms of polyarteritis nodosa?

What are the symptoms of polyarteritis nodosa?

Ployarteritis nodosa: Symptoms depends on organ or system affected. Symptoms are fatigue , fever, muscle , joint pains, unexplained weight loss, anorexia . Based on organ involved kidney failure, hypertension due to kidney involvement, stroke , seizures due to brain involvement, abdominal pain due to bowel perforation , chest pain , heart attack due to heart involvement wrist drop, foot drop due nerve involvement. ...Read more

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Can polyarteritis nodosa lead to vasculitic neuropathy?

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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What new research is there regarding vasculitis and polyarteritis nodosa?

What new research is there regarding vasculitis and polyarteritis nodosa?

Treatment.: Polaryarteritis & temporal arteritis, are found to be quite treatable without high dose Prednisone and all it's side effects. The new drugs are tnf-a inhibitors and new research shows quick remission in most cases. ...Read more

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Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more

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Is polyarteritis nodosa always an autoimmune disease?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It is immune mediated and exact cause is not known. ...Read more

See 2 more doctor answers
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I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

I have been diagnosed with polyarteritis nodosa although both biopsy and blood test have come back negative. Is this diagnosis likely to be correct?

Polyarteritis nodosa: Diagnosis made by symptoms and findings which may include elevated wbc, ESR , CRP and in some positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied . At times biopsy is targeted for affected tissues. ...Read more

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Does a cure exist for polyarteritis?

Does a cure exist  for polyarteritis?

No: Polyarteritis nodosa is a type of vasculitis (blood vessel inflammation) that is often fatal if untreated. Fortunately, medicines exist that can control the symptoms and the disease can go into remission. However, that is not a cure. ...Read more

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What are treatments for polyarteritis nordosa?

What are treatments for polyarteritis nordosa?

Polyarteritis nodosa: In pan damage is due to impaired blood supply to vital tissues as a result of inflammation of medium to small arteries . Goal of treatment is to reduce inflammation with Prednisone , and Cytoxan as main drugs. Other medications include methotrexate, Leflunomide and Rituxan (rituximab) . Problems due to pan need to be treated such as HTN , renal failure, seizures, stroke, bowel perforation , neuropathy etc. ...Read more

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Do you know good doctors in indiana for polyarteritis nordosa?

Do you know good doctors in indiana for polyarteritis nordosa?

Not specifically: Best to contact the local arthritis foundation office for roper referrals to a trained rheumatologist ...Read more

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Diagnosed with polyarteritis and i'm unable to work and i'm walking with a stick. Will I have this for life?

Polyarteritis Nodosa: "pan" is a type of vasculitis that causes inflammation of the blood vessels all over the body, affecting just about every organ imaginable. The inflammation can cause blockages of the arteries which leads to an interruption of blood flow and a variety of other issues depending on the organ affected. It is a chronic issue that is life-long, but it can be controlled with medication. Consult an md. ...Read more

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