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Doctor insights on: Januvia And Insulin

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How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

Diabetes: The four medications work in 4 different mechanisms with the end goal of keeping blood sugar under control. Would suggest taking Glimepiride in mornings, metformin & Byetta before meals & Lantus (insulin glargine) at bedtime. Goal fasting blood sugar of 100 & hba1c of 6.5 good luck. ...Read more

Dr. Quang Nguyen
2,759 doctors shared insights

Insulin (Definition)

A hormone produced in the pancreas by the islets of langerhans that regulates the amount of ...Read more


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Does novorapid and lantus (insulin glargine) work well for diabetes?

Does novorapid and lantus (insulin glargine) work well for diabetes?

Yes: These are two very good Insulin frequently used in the treatment of both type of diabetes. ...Read more

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Amaryl (glimepiride) to control blood sugars?

Amaryl (glimepiride) to control blood sugars?

For type 2 diabetes: Amaryl (glimepiride) is an oral medication which helps the pancreas make more Insulin in patients with type 2 diabetes. ...Read more

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I'm on metformin, lantus (insulin glargine) n novolog. Can i replace the lantus (insulin glargine) n novolog w byetta to help w weight gain n still get the same sugar control?

I'm on metformin, lantus (insulin glargine) n novolog. Can i replace the lantus (insulin glargine) n novolog w byetta to help w weight gain n still get the same sugar control?

Only with supervisio: Please contact your health care professional about making changes in your diabetic therapy. Byetta can be helpful in controlling diabetes, but may not solve your weight gain problem. That should be controlled, under supervision, with diet and exercise. ...Read more

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I have type 2 diabetes and take novalog and lantus (insulin glargine). Do these insulins actually cause weight gain?

Maybe: If your diabetes is not controlled prior to using Insulin expect to gain a few pounds as your diabetes is intensified. Drugs such as metformin, liraglutide, canagliflizin, and pramlintide used in combination with Insulin can minimize wt gain. ...Read more

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Changing insulin from humalog (insulin lispro) to novolog - any effect?

Changing insulin from humalog (insulin lispro) to novolog - any effect?

Congratulations: Great move. Well, NovoLog is quicker acting but also quicker getting out of your system. So make sure you eat as soon as you inject. As with any insulin, proper close titration is necessary to avoid hypoglycemia and wild fluctuations in your sugar levels. Overall, best short acting Insulin on the market at present, and the most physiologic. ...Read more

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Novorapid and lantus (insulin glargine) solostar insulin availability. Where can I get some?

Novorapid and lantus (insulin glargine) solostar insulin availability. Where can I get some?

First need rx: Would discuss with your local doctor as you would need a prescription for the medications. Your local doctor /pharmacist should be able to point you in the right direction and discuss co-payment / costs of the medications given your insurance status, etc ...Read more

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Does Lantus (insulin glargine) Insuline inyections cause weight gain?

Does Lantus (insulin glargine) Insuline inyections cause weight gain?

Lantus (insulin glargine): I am assuming that your insulin injections have been started not long ago. Injections should not cause weight gain but there is a more important issue. Type 2 diabetes can and should be corrected such that you no longer have diabetes. Insulin injections should not cause weight gain. With that in mind, talk to your doctor about diabetes and also have a dietitian help you with your weight. ...Read more

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How dose amaryl (glimepiride) affect blood sugar, insulin?

How dose amaryl (glimepiride) affect blood sugar, insulin?

Lowers blood sugar: Amaryl (glimepiride) stimulates the pancreas to release insulin, which will cause the blood sugar to fall. This release of Insulin occurs without relation to whether one has eaten, so if one goes a long period without eating, the blood sugar can become abnormally low. ...Read more

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Is the glipizide more effective than glyburide and januvia (sitagliptin)?

Is the glipizide more effective than glyburide and januvia (sitagliptin)?

No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor. ...Read more

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How does insulin n differ from insulin glulisine and glargine?

How does insulin n differ from insulin glulisine and glargine?

NPH: Nph is not a basal insulin, as it doesn't work for longer than 12-16 hours and has a definite peak. I needs to be given twice/day. Glargine is a basal Insulin that lasts for 24 hours and has no peak. It can be given once/day. It is much better and safer than nph>. ...Read more

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Are special advantages of janumet (sitagliptin and metformin) over metformin?

Are special advantages of janumet (sitagliptin and metformin) over metformin?

GLP -1 analogues: Janumex is a pill which combines januvia (sitagliptin) in addition to metformin so it combines two different ways glucose is lowered in your blood stream januvia (sitagliptin) lowers glucagon after eating and decreases blood glucose after eating and complements metformin which lowers mainly fastingsome adverse publicity around januvia (sitagliptin) related to pancreatitis the jury is still out. ...Read more

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Why do you have to give gliclazide and lantus (insulin glargine) together. Isn't lantus (insulin glargine) enough to lower blood sugar? Also why give these medications before food?

Why do you have to give gliclazide and lantus (insulin glargine) together. Isn't lantus (insulin glargine) enough to lower blood sugar? Also why give these medications before food?

Too much 4 400 space: 1st drug stimulates your own insulin production. 2nd is long lasting insulin. There are multiple forms of insulin with different half lives and there are also insulin pumps which automate a lot of this stuff. ...Read more

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How janumet (sitagliptin and metformin) is beneficial compared to just metformin?

Janumet (sitagliptin and metformin) is : Metformin plus what is called a dpp-4 inhibitor, which stimulates Insulin release, blocks hormones that raise your sugar and makes the combo w/metformin more potent at lowering your blood sugar. ...Read more

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Humalog (insulin lispro) insulin not taking effect, what to do?

Humalog (insulin lispro) insulin not taking effect, what to do?

Easy!: Hi. Easy! Increase the dose! We usually start low to keep hypoglycemia risk in check. So advance the dose until you get the effect you're after. Use you blood sugar testing frequently to make using Humalog (insulin lispro) effective & safe. Good luck! ...Read more

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How do insulin and glucagon control blood sugar levels?

How do insulin and glucagon control blood sugar levels?

Opposite action: Insulin will deliver glucose to the cells of your body and has the potential to cause hypoglycemia. In the presence if hypoglycemia or with fasting, glucagon is the hormone secreted which will stimulate glycogen (stored glucose) conversion to glucose in order to keep body fuel supply going. ...Read more

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Insulin pen or insulin pump which is better?

Insulin pen or insulin pump which is better?

Depends on you: Taking Insulin by injection or by pump are both good options. There are very many well-controlled people with diabetes who do each. The primary question is which of the two ways of delivering Insulin will work best for you. People like using Insulin pumps because it simplifies the math associated with accurate testing and because it offers more flexibility in hour by hour and day by day dosing. People like injections because they are simpler and do not require being tethered to a device all the time. ...Read more

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Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Yes: Hi. Metformin and sitagliptin work via different mechanisms, and together are synergistic. So yes, more effective than one drug alone. Note even the combination may not be adequate for achieving tight control. Your doctor will follow your A1c response, and if it's in the mid-low 6's, you're good to go. A nice thing is Janumet (sitagliptin and metformin) by itself cannot cause hypoglycemia. Good luck! ...Read more

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I was recently switched from januvia (sitagliptin) to lantis insulin and almost immediately developed extremely hig blood pressure attacks as high as 257?

I was recently switched from januvia (sitagliptin) to lantis insulin and almost immediately developed extremely hig blood pressure attacks as high as 257?

Not due to Lantus (insulin glargine): The sudden rise in BP should not occur with lantus (insulin glargine). Check w/your physician. By the way, you can continue januvia even while using Insulin -- they work well together. ...Read more

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I was recently switched from januvia (sitagliptin) to lantis insulin and almost immediately developed extremely hig blood pressure attacks as high as 257. Normal?

I was recently switched from januvia (sitagliptin) to lantis insulin and almost immediately developed extremely hig blood pressure attacks as high as 257. Normal?

Blood pressure?: Do you mean blood pressure of 257 or blood sugar of 257? Lantus (insulin glargine) should not cause elevation in blood pressure unless you took it right after the injection which in that case is due to anticipation of the shot (but that's still very high- check your BP cuff). If blood sugar, i wouldn't focus on one number but rather the trend through the day with lantus (insulin glargine). ...Read more

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Is it real that januvia (sitagliptin) 100mg made pancreas cells produce more insulin ( made beta cells more active )?

Incretin: Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4. Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon. ...Read more

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Can i eat grapefruit while taking januvia (sitagliptin)?

Can i eat grapefruit while taking januvia (sitagliptin)?

Yes: There should be no problem with eating grapefruit while on januvia (sitagliptin). Other meds like some statins, some antibiotics, some heart meds, and some cancer meds can be affected by grapefruit juice. ...Read more

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How tell when januvia (sitagliptin) isn't right for you.

Well: Does it control your blood sugars? Does it make you feel bad after you take it? If your blood sugars are controlled and you are doing you part to follow your diabetic diet and it does not make you feel bad then it is a good med for you. ...Read more

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What is a good time of day to take januvia (sitagliptin)?

Best in am: before breakfast as its greatest benefit is reducing sugars after eating ...Read more

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When during the day is it optimal to take januvia (sitagliptin)?

Morning: So you don't forget it and it works during the portion of the day when you take in your food. ...Read more

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What is a med similar to januvia (sitagliptin) that does not make you gain weight?

Januvia (sitagliptin): Meds for control of diabetes very infrequently "cause" weight gain. The weight gain is more related to diet and exercise. Are your blood sugars staying in the normal range? How often are you checking? There are many more questions to ask you but it would be best if you set up an appointment with a diabetes educator. ...Read more

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Help please? What is the sister med to januvia (sitagliptin) that does not make you gain weight?

Many drugs: Januvia (sitagliptin) is a DPP4 inhibitor. Other DPP4 inhibitors are alogliptin, saxagliptin, linagliptin. None of these increase weight (on average..everyone is different). You may be thinking about the injectable incretin agonists, Exenatide (Byetta) and liraglutide (Victoza). These drugs often result in some weight loss. ...Read more

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What are the side effects of taking januvia (sitagliptin)?

Few;low blood sugar: The most common side effects of Januvia are low blood sugar and headache. If you experience any of these side effects or any signs of being allergic to the medication (itching/rash), and they become too bothersome to manage, feel free to speak to your doctor about it, but this drug is usually very well tolerated by patients. ...Read more

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Januvia 100mg is the equivalent to how much victoza (liraglutide)?

No conversion: Hi. There is no standard conversion factor between Victoza (liraglutide) and Januvia. Victoza (liraglutide) is much more efficacious and also causes weight loss, which Januvia does not. Victoza (liraglutide) can cause nausea and general GI problems, whereas Januvia causes no GI problems. eat healthily and exercise regularly. Control your diabetes well. Good luck! ...Read more

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Is their really any difference between onglyza (saxagliptin) and Januvia?

Onglyza (saxagliptin) vs januvia: Yes, there may be some difference. What is your current diabetes status? Please let me know and we can discuss this by email (dansjake@gmail.com). ...Read more

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I have HBP and been taking Januvia, (sitagliptin) is it known to raise you BP ?

BP: Not to my knowledge. That said blood pressure issues are not related directly to Januvia (sitagliptin). Please discuss with your doctor - you may need special attention to the BP. ...Read more

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I am taking 100mg of januvia (sitagliptin) daily. Am i at risk of getting pancreatitis?

I am taking 100mg of januvia (sitagliptin) daily. Am i at risk of getting pancreatitis?

Low: Diabetic in general are at higher risk of developing pancreatitis compared to the general population. No studies so far had conclusively found januvia (sitagliptin) to cause pancreatitis. In clinical practice, we ask our patients to tell us right away if they experience mid epigastric pain while on the drug. We will evaluate then. ...Read more

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I took two 100 milligram tablets of januvia (sitagliptin) in less than 4 hours apart .My sugar was 385, should I be worried?

I took two 100 milligram tablets of januvia (sitagliptin) in less than 4 hours apart .My sugar was 385, should I be worried?

Consider going to: An urgent care for Insulin shot. If u have severe symptoms like nausea, vomiting, dizziness, abdominal pain, go see a dr right away. Take care and god bless u! http://inhealth.Cnn.Com/getting-diabetes-under-control/12-signs-of-uncontrolled-diabetes/ http://www.Thirdage.Com/diabetes/best-10-herbs-and-supplements-diabetes. ...Read more

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Can januvia (sitagliptin) cause stiff joint?

Can januvia (sitagliptin) cause stiff joint?

Yes: Yes, but it is debated whether the drug causes joint stiffness on its own or if the drug makes joints that are already arthritic feel stiff. ...Read more

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I'm taking the drug januvia (sitagliptin) for type 2 diabetes is this a safe drug to take?

I'm taking the drug januvia (sitagliptin) for type 2 diabetes is this a safe drug to take?

Very safe: Januvia (sitagliptin) has very few side effects. Unlike some other diabetes drugs (glipizide, Insulin etc) it does not cause hypoglycemia attacks, nor increase appetite and weight. There have been rare reports of pancreatitis but these have not been confirmed in clinical trials, and may be simply due to the fact that patients with diabetes are more likely to get pancreatitis irrespective of treatment. ...Read more

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What is all the controversy over januvia (sitagliptin). And abilify? (serious complications?)

Januvia (sitagliptin) risks: Januvia (sitagliptin) has been reported to cause an increase in renal failure, pancreatitis, and pancreatic cancer. Abilify can raise blood sugar levels and cause diabetes as well as interfere with the effects of januvia (sitagliptin). Best wishes.0. ...Read more