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Doctor insights on: Janumet Sitagliptin Metformin

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Are special advantages of janumet (sitagliptin and metformin) over metformin?

Are special advantages of janumet (sitagliptin and metformin) over metformin?

GLP -1 analogues: Janumex is a pill which combines januvia (sitagliptin) in addition to metformin so it combines two different ways glucose is lowered in your blood stream januvia (sitagliptin) lowers glucagon after eating and decreases blood glucose after eating and complements metformin which lowers mainly fastingsome adverse publicity around januvia (sitagliptin) related to pancreatitis the jury is still out. ...Read more

Dr. David Sneid
1,046 Doctors shared insights

Metformin (Definition)

That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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How janumet (sitagliptin and metformin) is beneficial compared to just metformin?

Janumet (sitagliptin and metformin) is: Metformin plus what is called a dpp-4 inhibitor, which stimulates Insulin release, blocks hormones that raise your sugar and makes the combo w/metformin more potent at lowering your blood sugar. ...Read more

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Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Yes: Hi. Metformin and sitagliptin work via different mechanisms, and together are synergistic. So yes, more effective than one drug alone. Note even the combination may not be adequate for achieving tight control. Your doctor will follow your A1c response, and if it's in the mid-low 6's, you're good to go. A nice thing is Janumet (sitagliptin and metformin) by itself cannot cause hypoglycemia. Good luck! ...Read more

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Is janumet (sitagliptin and metformin) safe to take? I am type 2 diabetic.

Generally yes: Janumet (sitagliptin and metformin) is safe as long as you tolerate metformin without problem and have relatively normal kidney function. Your doctor can help you out with these questions and check your lab to see if you're appropriate. ...Read more

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I'm on Janumet (sitagliptin and metformin) and have bronchitis. What meds can I take.

I'm on Janumet (sitagliptin and metformin) and have bronchitis. What meds can I take.

See link: Http://www. Drugs. Com/drug-interactions/metformin-sitagliptin, janumet (sitagliptin and metformin).html
This link offers info on medications you should not take or to be careful taking if you are on Janumet (sitagliptin and metformin). Not sure if you are referring to prescription or OTC meds.
Also good idea to discuss with your treating doctor.
Hope this is helpful. Thanks for using Healthtap and hope your bronchitis is better soon. Dr R ...Read more

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I am type 2 diabetic from last 7 yrs how safe is janumet (sitagliptin and metformin) 50/1000mg. I take it twice daily....

Safe, however...: ... you should only take with regular monitoring by your doctor. Janumet (sitagliptin and metformin) is a combo-drug formed by adding sitagliptin (aka, Januvia) and metformin, hence the combo brand name (and combo price tag). It has a BLACK BOX WARNING for potential lactic acidosis which can occur due to metformin accumulation. This is rare, but fatal in 50% of cases, esp. In diabetics w/ kidney disease. Talk w/ your doctor. ...Read more

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I am taking janumet (sitagliptin and metformin) 50/1000 twice in a day still my sugar level is 220 any better tablet you can advice me please?

I am taking janumet (sitagliptin and metformin) 50/1000 twice in a day still my sugar level is 220 any better tablet you can advice me please?

Sorry, no.: I'm sure you've heard the advice: "Don't change your medication except on the advice of your physician." We are NOT your physician and it would be unprofessional for us to give you such specific advice. Talk to your doctor about diabetes medications and other ways (such as diet & exercise) you can control your blood sugar. Best wishes. ...Read more

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Any complications from taking janumet (sitagliptin and metformin) for type 2 diabetes?

Minor: You can have GI problems from the metformin, and uncommon other problems from either component of the drug -- just like any and all medicine. Otherwise, it's one of the safest medications ever. ...Read more

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I'm taking janumet (sitagliptin and metformin) for diabetes and my sugar level is still high what do I need to do?

I'm taking janumet (sitagliptin and metformin) for diabetes and my sugar level is still high what do I need to do?

See doctor: You need to see doctor so your med dosage can be increase to stronger one or change to a combination drug such as janumet in which it has januvia (sitagliptin) and metformin together. ...Read more

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My husband is taking Janumet, (sitagliptin and metformin) which is controlling his diabetes. He now has mild diarrhea. What can he do reduce the side effects?

My husband is taking Janumet, (sitagliptin and metformin) which is controlling his diabetes. He now has mild diarrhea. What can he do reduce the side effects?

Janumet (sitagliptin and metformin): Mild diarrhea is unlikely to be related to Janumet (sitagliptin and metformin). Your husband must see his doctor about the diarrhea.
Please keep me informed. ...Read more

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I am diabetic and walk daily 30-45mins but want should I take for my breakfast. I am 47 years old. Currently taking janumet (sitagliptin and metformin) 50/1000?

Glucose control: Lose weight by diet and exercise. Keep your glucose in control. Janumet (sitagliptin and metformin) is fine - need to be taken twice per day unless it's the xr. You may need additional medication as well. Check with your doctor. ...Read more

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I am taking janumet (sitagliptin and metformin) 1000 mg twice a day (250 pp) with lipicure tag for high cholesterol 252 for 20 days....Still sugar level is 225 pop and 158 fast?

I am taking janumet (sitagliptin and metformin) 1000 mg twice a day (250 pp) with lipicure tag for high cholesterol 252 for 20 days....Still sugar level is 225 pop and 158 fast?

New appointment: Your post-prandial blood sugars should be down into the 100s 2h after meals. You may need triple diabetes therapy with januvia (sitagliptin), (sitagliptin) metformin, and actos. A1c should be 7.0 or lower. You may need to add Zetia to the Lipitor to reach your lipid goals. Always observe proper lifestyle changes with low-carb, low-fat, prudent diabetic diet; and weight loss with exercise! Consider Bydureon instead of januvia (sitagliptin). ...Read more

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Iam on janumet (sitagliptin and metformin) od in morning. I often take alcohol like 3or 4 drinks. Please let me know the exact gap between metformin and alcohol intake?

Iam on janumet (sitagliptin and metformin) od in morning. I often take alcohol like 3or 4 drinks. Please let me know the exact gap between metformin and alcohol intake?

A 2 hour gap should: Be ok. Remember that alcohol can raise your sugar level so balance the pros and cons of dietary restriction and freedom. Attain an a1c near 6 or 7, as well as ideal body weight, good blood pressure and lipid control. Stay active and exercise on a regular basis. Have an ekg annually or whenever u have chest pain. Have fun! ...Read more

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Hello Dr. I am a type 2 diabetic, I take Janumet (sitagliptin and metformin) 1000/50 two times per day. I was put on seroquel xr and have noticed an increase in my blood sug?

Hello Dr. I am a type 2 diabetic, I take Janumet (sitagliptin and metformin) 1000/50 two times per day. I was put on seroquel xr and have noticed an increase in my blood sug?

Type II Diabetes: Is clearly on the rise, even in children. It can be reversed w/lifestyle changes but it takes hard work. Please do what your doc asks and give him/her feedback on your numbers. Consider food plan and exercise program w/guidance from doc or nutritionist. Peace and good health. ...Read more

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Type 2 on janumet, (sitagliptin and metformin) 28 male. Sometimes in parties I have to eat unhealthy (high carbs). Always on tight diet & exercis. If bs increase after a party.?

Type 2 on janumet, (sitagliptin and metformin) 28 male. Sometimes in parties I have to eat unhealthy (high carbs). Always on tight diet & exercis. If bs increase after a party.?

No ones perfect/?: I'm not sure I completely understand your?, but as an insulin dep diabetic on Janumet (sitagliptin and metformin) you are on pretty tx. No fixed dose medication will completely control your sugar if you have a high carb meal. Janumet (sitagliptin and metformin) usually does a pretty good job helping. There are ways of adjusting your tx based on carbs. That said no one is perfect and an occasional cheat as long as not crazy high sugar is OK & nl. ...Read more

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I am diabetic patient for lat 10 years. For last 4 years taking Glucovance and Janumet (sitagliptin and metformin). from last month insuline. Avarage sugar 13. Natural remidy?

Diabetes treatment: Was "13" your A1C? If so, that is very high, and it means your diabetes is under poor control. The only natural remedy would be a diet that resulted in significant weight loss, if you are overweight. See your doctor. Did you start insulin? You may need more, or a different timing of shots. ...Read more

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Male, 29, diabetic (MODY hba1c 6.5, janumet (sitagliptin and metformin) once and metfor 500mg at night) Whenever I travel say around 70km or more my sugar increase over 220 mgdll?

Need more info: YIf you truly have MODY with a strong family history of the same, I would need to know what type. If type 3 (most common) the best treatment is not janumet (sitagliptin and metformin) (metformin and Januvia) but a type of drug called a sulfonylurea like glyburide. No reason why traveling 70 km should increase BG except if you are driving and snacking a lot while you driving. ...Read more

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Have had loose stool for about a month now on janumet, (sitagliptin and metformin) blood levels and colesterol good, but stool very runny all the time?

Have had loose stool for about a month now on janumet, (sitagliptin and metformin) blood levels and colesterol good, but stool very runny all the time?

Not uncoomon: Janumet is a combination medication with januvia (sitagliptin) and metformin. Gi side effects are not uncommon with metformin especially at higher doses. ...Read more

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Can I continue with amaryl 2 mg and discontinue janumet (sitagliptin and metformin) as it gives me stomach discomfort?

Can I continue with amaryl 2 mg and discontinue janumet (sitagliptin and metformin) as it gives me stomach discomfort?

Talk to your doctor: Tell your doctor about the stomach discomfort so that he/she can evaluate and prescribe a different regimen. You might want to break the janumet into januvia (sitagliptin) and metformin and eliminate one drug at a time to see which one is causing the discomfort. In any case. Don't stop meds without letting your doctor know about it. ...Read more

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What are the signs of stomach related headache. I have headache on top part or head with nausea. Also Taking Janumet (sitagliptin and metformin) for two weeks now?

What are the signs of stomach related headache. I have headache on top part or head with nausea. Also Taking Janumet (sitagliptin and metformin) for two weeks now?

Janumet (sitagliptin and metformin) side effect?: Without more history it's uncertain if you headache and nausea are related. You may be having an adverse effect of Janumet (sitagliptin and metformin) which can cause both symptoms. See your Dr ...Read more

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I recently started taking janumet (sitagliptin and metformin) for diabetes and I have had ridiculous heartburn and diarrhea. My doctor advised me to take it once a day with food.

I recently started taking janumet (sitagliptin and metformin) for diabetes and I have had ridiculous heartburn and diarrhea. My doctor advised me to take it once a day with food.

Yes: The medication that you were prescribed can certainly cause these symptoms and some people. Please talk to your health care provider about perhaps starting with just half a pill each day ...Read more

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What to do if I do not use drugs and I am diabetic. I take janumet XR (sitagliptin and metformin) does this have anything to do with it?

Diabetic: First of all you most likely have type 2 diabetes. If so you are not a diabetic - you have diabetes - and you should be working for the next several years to rid yourself of diabetes.
Diet, exercise, and decreasing medication doses for management of diabetes if where you should be.
Yes, it is possible and I would add - essential!
Please keep me posted! ...Read more

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Can I take janumet XR (sitagliptin and metformin) and doxycycline at the same time? Thanks in advance.

Can I take janumet XR (sitagliptin and metformin) and doxycycline at the same time? Thanks in advance.

Drug interaction: Checker reveals no significant interactions between Janumet Xr (sitagliptin and metformin) and doxycycline. ...Read more

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Can frequent diarrhea prevent the absorption of meds? Am on janumet xr, (sitagliptin and metformin) have diarrhea multiple times a day, regardless of diet changes.

Can frequent diarrhea prevent the absorption of meds? Am on janumet xr, (sitagliptin and metformin) have diarrhea multiple times a day, regardless of diet changes.

Yes: The diarrhea is not the problem. Whatever is causing you to lose a lot of water in your intestinal track may be interfering with the full absorption of some medications. Continuous diarrhea may cause a life-threatening condition as you lose important electrolytes in addition to water. See a doctor to evaluate the cause of diarrhea, which may include the medication you are taking. ...Read more

Dr. Walter Futterweit
695 Doctors shared insights

Glucophage (Definition)

Glucophage is a diabetes-related agent which is a kind of ...Read more


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