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Doctor insights on: Ivf Increase Risk Of Down Syndrome

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Dr. Amrita Dosanjh
3 doctors shared insights

Ivf (Definition)

In vitro fertilization is an assisted reproductive technology. Ivf is a procedure used to treat fertility problems and assist with the conception of a child. During ivf mature eggs are retrieved from the ovaries and fertilized by sperm in a lab. A few days later, the fertilized egg (embryo) or eggs are implanted into the uterus. One cycle of in vitro fertilization ...Read more


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Im 28 with an IVF pregnancy. My blood work came back with a high chance of down syndrome. Someone said it might be from the ivf?

Im 28 with an IVF pregnancy. My blood work came back with a high chance of down syndrome. Someone said it might be from the ivf?

Not from ivf: Down syndrome is a chromosome defect (trisomy or translocation). It is usually sporatic without cause. It can be familial or related to maternal age. The ivf process does not cause this defect, but the ovum and sperm used may already have the defect. Direct evaluation of fetal cell dna will be necessary to confirm the diagnosis. ...Read more

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Can a 20 week Anatomy ultrasound pick up down syndrome in the baby ? I have an increased risk of a 1 in 89 chance of having my baby born with DS

Can a 20 week Anatomy ultrasound pick up down syndrome in the baby ? I have an increased risk of a  1 in 89 chance of having my baby born with DS

Didn't you ask this?: Your risk assessment was obsolete, Ultrasound detection of Down at 20 weeks misses many. Demand a test of freei fetal DNA in your blood sample--your PCP can order the Harmony test from Ariosa: call 1-855-9-ARIOSA (855-927-4672) In over 15,000 pregnancies they detected 100% of Down syndrome and the chance of a false positive was less than 1 in 1000. Results in 4 to 8 days. ...Read more

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Does Down syndrome increase your risk for leukemia?

Yes: Down syndrome unfortunately leads to an increased risk of acute myeloid (especially megakaryocytic) and acute lymphocytic leukemias. The risk of acute leukemia in the first 5 years of life is 56x higher than non-downs kids and overall, 1 in 150 downs patients develop leukemia. ...Read more

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Why would maternal age be associated with an increase in errors that lead to down syndrome?

Why would maternal age be associated with an increase in errors that lead to down syndrome?

A woman's eggs are : as old as she is. An embryo receives ½ it's chromosomes from Dad & ½ from Mom. DNA replicates in each parental chromosome pair & crosses over between 2 sister chromatids joined in the center that then split into egg cells. At 35 & >, cohesion of maternal sister chromatids is progressively impaired, ^ing the risk of an egg's receiving 2 or 0 copies of a chromosome. Her 2 + Dad's 1 Chr. 21 = DS ...Read more

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Why does the risk of having a Down syndrome baby increase for women over 35 years of age?

Why does the risk of having a Down syndrome baby increase for women over 35 years of age?

Aging: There is a risk for a baby with down syndrome at all ages, not just in women over 35. The risk gradually increases with age. It has to do with how the egg and sperm half the chromosomes so the next generation has the same number of chromosomes as the parents. ...Read more

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I have 26 yr old Down syndrome daughter who is on Effexor (venlafaxine) 225 mg for depression, ocd. She is not eating well, refusing many foods , dose just increase?

I have 26 yr old Down syndrome daughter who is on Effexor (venlafaxine) 225 mg for depression, ocd.  She is not eating well, refusing many foods , dose just increase?

Effexor (venlafaxine) may be cause: Effexor (venlafaxine) may be the cause. Whenever an adjustment in dose or changing a medication results in a change in behavior, you have to consider the change as the cause. Speak to your daughter's prescriber about an alternative to Effexor (venlafaxine). ...Read more

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Dr. Kathryn Akin
641 doctors shared insights

Down Syndrome (Definition)

Down syndrome is the classic presentation clinically of the congenital malformation syndrome also known as Trisomy 21. Classic features may include simian creases, epicanthal folds, upslanting palpebral fissures, flat nasal bridge, hypertelorism, low set ears, endocardial cushion defects of the heart, atlanto-axial joint instability, blood ...Read more


Dr. Gerard Honore
496 doctors shared insights

Ivf Pregnancy (Definition)

In-vitro fertilization is a process where the egg and sperm are united outside of the woman's body, in a laboratory setting. Some of the resulting embryos are then implanted ...Read more