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Doctor insights on: Ivabradine

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Why ivabradine is not available in the u.S.?

Why ivabradine is not available in the u.S.?

Not submitted to FDA: Ivabradine has been approved for
marketing for patients with angina by several regulatory agencies throughout the world. The drug has never been submitted for review by the fda because the french manufacturer, servier, lacked an american subsidiary to market the drug. However in july 2013, amgen announced that it had obtained commercial rights in the U.S. To this novel oral drug for further tests. ...Read more

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How long does it take ivabradine tablet to work before achieving stable level?

How long does it take ivabradine tablet to work before achieving stable level?

Probably 3 days: But you are young for this beta blocker for blood pressure or heart failure, I don't know why you are on this unless you had a heart attack or the above, maybe heart racing? See a cardiologist to be sure you have the right medicine but it should be stable within 3 days or less. ...Read more

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How long does it take Ivabradine to work? Is the effect immediate, or does it still stabilize over several days?

How long does it take Ivabradine to work? Is the effect immediate, or does it still stabilize over several days?

Manufacturer website: Corlanor® (ivabradine) is indicated to reduce the risk of hospitalization for worsening heart failure in patients with stable, symptomatic chronic heart failure with left ventricular ejection fraction ≤ 35%, who are in sinus rhythm with resting heart rate ≥ 70 beats per minute. Read more at: https://www. Corlanorhcp. Com ...Read more

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Why is ivabradine not fda approved?

Ivabradine: From what I can find, the cost to the company making it in france to get it approved in the us would not be worth the investment for them so what I've read doubts it will be presented with appropriate data to the fda to consider. ...Read more

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Iam taking ivabradine (corolan) could take also 50mg of metoprolol?

Iam taking ivabradine (corolan) could take also 50mg of metoprolol?

Ivabradine: Ivabradine can be used selectively in some patients along with beta blockers if it is appropriate for them. ...Read more

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I walk daily for around 45 mins. I take ivabradine 5 mg daily once after lunch. Do I have anything to worry, health wise?

I walk daily for around 45 mins. I take ivabradine 5 mg daily once after lunch. Do I have anything to worry, health wise?

Ivabradine: You'll have to ask your doctor who knows you and your history and data that question. If you're on that drug it is used for angina pectoris mostly and for CHF in some patients. If you're taking it for some other reason...? It isn't a drug most of us would prescribe if you don't have some kind of problem that will be helped by it. ...Read more

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I ran out of my ivabradine. My heart was beating so hard. Can I replace it by taking bb? I used to take them before. Cant reach my ep till thursday.

I ran out of my ivabradine. My heart was beating so hard. Can I replace it by taking bb? I used to take them before. Cant reach my ep till thursday.

Sort of, but no: Ivabradine is a truly novel medicine; it works in a way no other medicine available does. (for that matter, it's not avail in the us... Where did you get it? I have a few patients who'd love to know). Anyway, a beta blocker will have some effect on rhythm, but if so, via a totally different mechanism and potentially with some side effects. I'd call the office. ...Read more

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Taking tambocor (flecainide) & ivabradine for 2 years. Is it ok stop both suddenly. I want a baby but doctor refusing to stop or change my meds.

Taking tambocor (flecainide) & ivabradine for 2 years. Is it ok stop both suddenly. I want a baby but doctor refusing to stop or change my meds.

Only: A doctor who knows you and your history on person can tell you if you can start or stop medicines; online recommendations likely won't be helpful. ...Read more

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Just switched back from lopressor (metoprolol tartrate) 50 mg to ivabradine 5 mg. Hr 60 but now I feel my heart beating irregularly. Normal reaction? Should I be concerned?

Just switched back from lopressor (metoprolol tartrate) 50 mg to ivabradine 5 mg. Hr 60 but now I feel my heart beating irregularly. Normal reaction? Should I be concerned?

See your doctor: These symptoms can only be adequately addressed by your doctor in real-time (face-to-face). Only after a thorogh evaluation, possibly including labs and other studies, can he/she determine what's wrong and what to do about it. ...Read more

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Have sinus tachycardia all cardiac test normal holter recently show sinus tachycardia 140bpm my BP 100/70, bb lower my BP is ivabradine good choise?

Have sinus tachycardia all cardiac test normal holter recently show sinus tachycardia 140bpm my BP 100/70, bb lower my BP is ivabradine good choise?

Most likely cause: Is in the control mechanisms of the autonomic nervous system. These controls are situated on the lower part of the brain and the commonest cause of this is poor diet, particularly all the sweet staff. ...Read more

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Started ivabradine 2.5mg and having burning sensation in chest and cold clammy hands and feet & feeling sleepy?

Started ivabradine 2.5mg and having burning sensation in chest and cold clammy hands and feet & feeling sleepy?

Call your doctor: Who prescribed the ivabradine, can be unrelated or due to another drug you are on, or due due to a drug-drug interaction, best wishes ...Read more

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I'm having a CT heart angiogrami. I have been given ivabradine 5mg (mild asthma) I'm worried re my heart slowing down too much. I have brain aneurysm.

I'm having a CT heart angiogrami. I have been given ivabradine 5mg (mild asthma) I'm worried re my heart slowing down too much. I have brain aneurysm.

Monitoring: The pulse is slowed enough to gather good images of the mobile heart and arteries.
They will watch BP and pulse carefully. ...Read more

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My father had CABG 2 yrs ago. He's taking procoralan and concor both in am. Procoralan is quite expensive. Is there any alternative meds w/ same effect?

My father had CABG 2 yrs ago. He's taking procoralan and concor both in am. Procoralan is quite expensive. Is there any alternative meds w/ same effect?

Ask cardiologist: There are always alternatives to treatments. Because this medication is a specialty medication not usually prescribed by primary care, ask your father's cardiologist for alternatives to procoralan. They should be able to come up with a reasonable choice. ...Read more

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I take amlodipine 2.5 and Ivabradine hydrochloride 5 for having blood pressure and feel like head will burst I feel that I will die with heart attack?

I take amlodipine 2.5 and Ivabradine hydrochloride 5 for having blood pressure and feel like head will burst I feel that I will die with heart attack?

High blood pressure: Is one driver of CVDs, including heart attacks. Primary drivers=NMR lipoproteins (other than very ↓ LDL & ↑ Large HDL-particle concentrations), ↑ed glucose (starting way below what is considered Diabetes) & HTN. Meds you are taking may ↓ BP & heart pain some, but do not prevent heart attacks. Low-fat, Hi-carb foods drive CVDs, DM, Ca & Obesity. Study the issues yourself & get better assistance. ...Read more

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