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Doctor insights on: Iui Vs Ai

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I'm 32 with no problems, male factor is 2% morph trying to conceive for 14 months. Had our 2nd IUI with 50 Clomid (clomiphene) neg. What's next step? Iui or ivf?

I'm 32 with no problems, male factor is 2% morph trying to conceive for 14 months. Had our 2nd IUI with 50 Clomid (clomiphene) neg. What's next step? Iui or ivf?

Depends: There are many different factors that goes into account when deciding about the best fertility treatment and it can't and should not be answered by simply advising yes or no ivf. I would suggest however to look into the possible underlying causes for the low morphology and try to improve it (if at all possible )before your next fertility treatment . Good luck! ...Read more

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Dr. Deborah Smith
298 doctors shared insights

Intrauterine Insemination (Definition)

Intrauterine insemination (iui) is where fresh or frozen partner or donor sperm is prepared or 'washed' to increase the sperm quality then gently injected through your cervix after a speculum exam, like a pap smear exam. It should be painless or cause mild cramping only. Iui helps with mild to moderate sperm problems. Iui preparations should have at least 2 million moving ...Read more


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Mild Azoospermia with 40 million/ml prgress-A grade, 25% motility & 12% morphology Plng to for ivf with donor eggs. Which is the best? Is ivf or icsi?

Mild Azoospermia with 40 million/ml prgress-A grade, 25% motility & 12% morphology Plng to for ivf with donor eggs. Which is the best? Is ivf or icsi?

Unclear...: Your reported findings of semen analysis is reasonable; azoospermia denotes no sperm in semen at all. Have you & sex partner been evaluated for contributing factors for infertility yet? Generally speaking, some 50% of infertility result from female factors, some 30% from male factors, and 20% from both sides. So, ask treating doctors more before considering IVF or ICSI. ...Read more

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Can patient undergo ovulation induction using gonal f (follitropin alfa) while using HRT mainly femoston 2/10 mg?

Can patient undergo ovulation induction using gonal f (follitropin alfa) while using HRT mainly femoston 2/10 mg?

Doesn't make sense: In most cases this would not make much sense, although it could depend on 'why' and 'how' the hrt was being used. Estrogens such as in hrt are sometimes used in stimulation protocols with gonadotropins (such as gonal f, (follitropin alfa) ) an oral progestin would be an unlikely element of most protocols. ...Read more

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5 failed IUI with letrozole, mild endo removed by laparoscopy, one miscarriage but conceived naturally after 2 yrs. IVF next or Iui with injectables?

5 failed IUI with letrozole, mild endo removed by laparoscopy, one miscarriage but conceived naturally after 2 yrs. IVF next or Iui with injectables?

No more IUI: Since you've failed 5 IUIs, it is no longer a good option for you, especially for someone with endometriosis. One reason patients with endometriosis not able to conceive naturally, is because the endometriosis will cause pelvic adhesion and tubal dysfunction. IVF is a much better option. If you are afraid of using drugs, you may choose natural cycle IVF or mild stimulation IVF. ...Read more

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Husband, 36yo, has noa, y chrom microdeletion. Mesa result = 5sperm per hpf. For icsi, should use fresh or frozen? Prev icsi failed. Mesa-et = 30days

Husband, 36yo, has noa, y chrom microdeletion. Mesa result = 5sperm per hpf. For icsi, should use fresh or frozen? Prev icsi failed. Mesa-et = 30days

See below: Your husband's condition is unfortunately difficult, and while you may be fortunate, icsi in your case has a rather high risk of being unsuccessful. Have you considered donor sperm or adoption? Good luck. ...Read more

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Azoospermia with 40 million count & 25% motility. Plng to for ivf with donor eggs. Which is the best? Is ivf or icsi? Which has highest success rate

Azoospermia with 40 million count & 25% motility. Plng to for ivf with donor eggs. Which is the best? Is ivf or icsi? Which has highest success rate

Low sperm count: Low sperm count is actually oligospermia. Azoospermia means NO sperm. With that said IVF's most complex and expensive option is ICSI but it does have a high success rate. ...Read more

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TTC,in fertility treatment for 3yrs- did 8 cycles of IUI.Doc say IVF is next.i m worried abt hormones used.want true opinon on cons of IVF n cancer ?

TTC,in fertility treatment for 3yrs- did 8 cycles of IUI.Doc say IVF is next.i m worried abt hormones used.want true opinon on cons of IVF n cancer ?

Long discussion: The decision to proceed with IVF is a hard one and should involve a detailed conversation with you fertility specialist. The risks should be discussed and weighed against your desire to have a child. The hormonal exposure during treatment is lower than the hormonal elevation you will experience during pregnancy Pregnancy causes a HUGE surge in hormones way beyond fertility medication. ...Read more

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Diminished ovarian reserve with low egg supply. Would u rec Clomid (clomiphene) with IUI or injectable with iui. I am 35 years old?

Yes, IVF is better: At age 39 with DOR, you may try few cycles Clomid (clomiphene) IUI, but IVF is a better option. The reason is with DOR, you don't have many embryos to work with. On the other hand, if you do IVF, you may bank embryos and do FET later. At age 39, I strongly recommend to do Pre-implantation genetic screening (PGS) of your embryos prior to transfer. It will increase your change of pregnancy and reduce miscarriage ...Read more

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5th IUI yesterday done with Clomid and higher dose of Gonal F (follitropin alfa). 33 million sperm and 2 follicles this IUI. Can this work or IVF required? Unexplained

5th IUI yesterday done with Clomid and higher dose of Gonal F (follitropin alfa). 33 million sperm and 2 follicles this IUI.  Can this work or IVF required?  Unexplained

IUI: Is your physician confirming ovulation? Before you move on to IVF, that question has to be answered. You may need an hcg injection to help cause ovulation. Also , you need to ask if follicles are right range for size (about 15-22mm). ...Read more

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Hsg- bilateral tubal opacity with no spillage; uterine cavity normal. How can I conceive? Does inj. Palcenterex help? Success rate of tuboplasty/ivf

Hsg- bilateral tubal opacity with no spillage; uterine cavity   normal. How can I conceive? Does inj. Palcenterex help? Success rate of tuboplasty/ivf

IVF: If both of your tubes are blocked the only fertility treatment that works is ivf. Success rate of ivf is high if you are young and if the only fertility issue that you have is the blocks tubes. Repairing your tubes is not recommended: it has a high failure rate as well as a very high risk of ectopic pregnancy. Injection will not help. Good luck.. ...Read more

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Day 3 estradiol 123.54 FSH 6.46 LH 4.38 prolactin 23.13 is this okey to conceive or iui?

Day 3 estradiol 123.54 FSH 6.46 LH 4.38 prolactin 23.13 is this okey to conceive or iui?

Hard to say, because: First, no blood testing for females tells you yes/no on iui, that is determined by the male sperm numbers. Second, although your numbers are all in a normal range, the Estradiol at 123 is much too high for day 3 - which means the fsh might be suppressed (and therefore look 'better.' ) sorry if this sounds complicated! ...Read more

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Gm my sperm count is 4m rapid speed is 2% morphology 6%.24 sperm survival test is nil.can I go for Icsi.we had 2previous failed Icsi.

Gm my sperm count is 4m rapid speed is 2% morphology 6%.24 sperm survival test is nil.can I go for Icsi.we had 2previous failed Icsi.

Recommend more testi: Very important to get tested for DAZ genetic test that looks at the areas of the Y chromosome that is important for sperm production and fertilization. Also would get chromosome tested if previously not done so. Other test for males include the DNA defragmentation assay and evaluation of free reactive oxygen species in the Soren sample. And in the blood for male, thyroid and prolactin hormones. ...Read more

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On IUI with inj. 1st cycle 125/225IU Follistim-3 follicles, 2nd cycle 200IU Follistim-1 follicle. 3rd IUI MD wants 450IU, is that dose too high?

On IUI with inj. 1st cycle 125/225IU Follistim-3 follicles, 2nd cycle 200IU Follistim-1 follicle.  3rd IUI MD wants 450IU, is that dose too high?

Not too high: It's still a standard dose, used frequently. Whether it's "too high" really depends on how you responded at lower doses., especially what your estradiol (estrogen) level peaked at. Trust your doctor, but ask him/her questions if unclear. Good wishes. ...Read more

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Mild pcos, open tubes (had HSG) getting ready to try IUI. No cyst or endo just slightly high testosterone. Can IUI work with pcos?

IUI: Yes. However, it would be wise to have an honest discussion with your fertility specialist to discuss success rates, etc. ...Read more

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How many eggs can be retrieved (average) on 150ml gonal f (follitropin alfa) per day for mid ovarian reserve woman age 32 with endometriosis?

How many eggs can be retrieved (average) on 150ml gonal f (follitropin alfa) per day for mid ovarian reserve woman age 32 with endometriosis?

Very difficult to : Say exactly. Not knowing anything about your history makes this difficult but in general we start with 225 total units of gonadotropins and in a 32 year old with endometriosis the range is wide: 0-15. I am not a fan of giving a precise number becuase there are so many variables involved... ...Read more

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Why take both Clomid (clomiphene) 3-7+75iu menopur cd 9-10? What is the diff. w/ this combo vs only clomid (clomiphene)? Does the ovu.date, or number of recruited eggs change?

Why  take both Clomid (clomiphene) 3-7+75iu menopur cd 9-10? What is the diff. w/ this combo vs only clomid (clomiphene)? Does the ovu.date, or number of recruited eggs change?

Yes: Taking Clomid (clomiphene) and FSH together helps with improving the lining of the uterus which is crucial for implantation. It also helps with increasing the number of dominant follicles. Good luck ...Read more

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Success rate of day 3 versus day 5 embryo transfer for IVF. Is one method more successful than the other?

Success rate of day 3 versus day 5 embryo transfer for IVF. Is one method more successful than the other?

Need more space: to give the full answer. Short answer: they're the same, it depends on the embryo number and embryo quality. Day 5 allows transfer of fewer embryos (less risk of multiples) while keeping rates at the sam level. Could write a book about this, please consult with your MD or could do an online consult full details. Your doc is always first choice! Good wishes. ...Read more

Dr. William Singer
1 doctor shared a insight

Iui (Definition)

Intrauterine insemination is when the sperm is washed and is subsequently placed in the uterus with a small catheter so that it's closer to the egg ...Read more