Doctor insights on:
Itp In Children
Is being diagnosed with cancer during pregnancy common? 26/f. Itp, ibs-d, hashimotos. 2 children, want #3 but afraid of cancer diagnosis when pregnant
ITP: Thrombocytopenia or low platelet level can be caused by so many things such as drugs, platelet consumption by clots, infections, vitamin deficiency, cancer related etc. Your doctor has to rule out all those possibilities and ultimately to do a bone marrow biopsy to eval bone marrow. See your md and discuss further re-diagnosis approach/treatment and other things you need to know re - itp. ...Read more
Symptom: Most of the time itp patients are asymptomatic and the only abnormality they have is the low platelet level on their blood counts. They can have bruising, tiny red dots on the skin, roof of the mouth etc- (ptechiae) or other type of bleeding such as bleeding in the gum, only if platelet level goes down really low-below 30k or so. ...Read more
Oral steroids: Idiopathic thrombocytopenic purpura is a condition in which autoimmune antibodies against platelets causes an increased rate of destruction. Platelets are needed for normal blood clotting. Heavy periods, nose bleeding, easy brusing, and a rash (purpura) may suggest this problem. Diagnosis requires a blood count and blood clottting studies. Treatment begins with steroids (prednisone). ...Read more
In the old days....: The "i" in itp stood for idiopathic, which means we didn't know what was causing the problem. We now know this to be an autoimmune process where antibodies recognize proteins on the surface of platelets and target them for destruction by the reticuloendothelial system. Most cases follow an infection (usually viral), but they can also be the presenting feature of autoimmune disorders or malignancy. ...Read more
In most cases, itp in children resolves on its own. Your child’s blood may be tested weekly or at longer intervals until the platelet count has returned to normal.
Treatment may be recommended based upon the platelet count, age of the patient, activity level and bleeding symptoms. When treatment is recommended, it may involve the following medications that help keep platelet counts at a safe leve. ...Read more
Bruising, bleeding: People with itp may be at an increased risk of bruising or bleeding, depending on the platelet count and other factors, such as medications. If needed, itp can be treated with steroids or other medications. In some instances, removing the spleen (splenectomy) may be recommended. If you are to require surgery, the surgeon should be made aware of this condition. ...Read more
Good question: What treatments have you had? The medical treatments have typically included steroids, other immunosuppressive medications, rituximab. These medications do not always work, and sometimes they only work temporarily. The main surgical treatment is splenectomy. This does not always work either. The goal is to keep you platelets high enough so that you are not having frequent bleeding. Good luck. ...Read more
Probably not: The risks are (1) heavy bleeding during delivery and with epesiotomy or ceaserean section and (2) maternal antibodies against platelets crossing the placenta and affecting your newborn's platelet count. These are issues best discussed with your ob/gyn and hematologist. For more information try http://www. Mayoclinic. Com/health/idiopathic-thrombocytopenic-purpura/ds00844/dsection=complications. ...Read more
No: Both itp and ttp are diseases in which blood platelet counts fall however, itp typically leads to an increased risk for bleeding but ttp results in blood clot formation in small blood vessels. These clots can damage the kidneys or cause stroke. Both diseases can be treated with plasmaphoresis, a procedure in which anti-platelet antibodies can be removed from the blood (a temporary measure). ...Read more
Can be, but rare: Most people w/ treated itp can expect to live a normal life span. Platelets help the blood clot, so a person w/ extremely low platelets (due to immune system attack in itp) can have fatal bleeding esp in the brain. However, this happens <1% of the time. Your doctor will monitor your platelets, and there are many treatments for itp such as Prednisone that can help maintain a good platelet count. ...Read more
Most patients are able to recover platelet counts and have a mortality rate similar to the general population. For more details see this link.
http://bloodjournal. Hematologylibrary. Org/content/97/9/2549.long. ...Read more