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Doctor insights on: Itp

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Dr. Steven Ginsberg
132 Doctors shared insights

Itp (Overview)

Idiopathic thrombocytopenic purpura (ITP) = bleeding disorder in which platelets are destroyed.


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What are the tests for itp?

What are the tests for itp?

ITP: Thrombocytopenia or low platelet level can be caused by so many things such as drugs, platelet consumption by clots, infections, vitamin deficiency, cancer related etc. Your doctor has to rule out all those possibilities and ultimately to do a bone marrow biopsy to eval bone marrow. See your md and discuss further re-diagnosis approach/treatment and other things you need to know re - itp. ...Read more

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Dr. Steven Ginsberg
132 Doctors shared insights

Itp (Overview)

Idiopathic thrombocytopenic purpura (ITP) = bleeding disorder in which platelets are destroyed.


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What are the symptoms of itp?

What are the symptoms of itp?

Symptom: Most of the time itp patients are asymptomatic and the only abnormality they have is the low platelet level on their blood counts. They can have bruising, tiny red dots on the skin, roof of the mouth etc- (ptechiae) or other type of bleeding such as bleeding in the gum, only if platelet level goes down really low-below 30k or so. ...Read more

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Platelet count: 160k/may 110k/august 92k/september 93k/november. Rest of blood report normal. No bleeding disorder in family. No other symptoms. Itp?

Platelet count: 160k/may 110k/august 92k/september 93k/november. Rest of blood report normal. No bleeding disorder in family. No other symptoms. Itp?

Maybe: One must question why blood tests are being done so often in a well 20 year old? Medications and certain conditions can lead to low platelets. Itp is 1 cause. An evaluation by a hematologist might be needed to determine the cause of a low platelet count. ...Read more

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What sort of tests will I need to test me for itp?

What sort of tests will I need to test me for itp?

ITP testing: A complete blood count (CBC) is usually ordered as the screening test for platelet destruction problems such as occurs in itp. Other testing is needed to confirm this diagnosis. ...Read more

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Does anyone knows how effective is rituximav if I have itp?

Response rate 20-30%: Recent review in blood in may 2012 looked at several articles and found a 5-year response rate in adults to be around 26%. Meaning these patients had a sustained elevation of their platelet count for 5 years. Initially the response rate is close to 60%. It is given weekly for 4 weeks. So in summary, it works well. Hope this helps. ...Read more

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Where do the antibodies that cause itp come from?

ITP: Idiopathic thrombocytopenic purpura is an autoimmune disorder meaning that there is a genetic flaw in the deep immunitiy (memory cell and t cell system) recognition system in regards to your platetets. ...Read more

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I have itp and just had my spleen removed. Does this now mean I don't have itp now more.

ITP: Some people still have refractory low platelet counts and up to 30% still require meds after splenectomy. ...Read more

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How do you treat itp in adults?

How do you treat itp in adults?

Oral steroids: Idiopathic thrombocytopenic purpura is a condition in which autoimmune antibodies against platelets causes an increased rate of destruction. Platelets are needed for normal blood clotting. Heavy periods, nose bleeding, easy brusing, and a rash (purpura) may suggest this problem. Diagnosis requires a blood count and blood clottting studies. Treatment begins with steroids (prednisone). ...Read more

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How effective is it to be treated with rituximab if itp (thrombocitopenic idiopathic purpura)?

Faily effective.: Most patients (30-40%) treated with Rituxan (rituximab) weekly x4 will develop normalization of their platelet counts. ...Read more

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What's the best treatment to get rid of itp?

Many options....: Traditionally, acute itp was treated with ivig, which leverages anti-idiotype effect and fc receptor engagement to block PLT degradation. Winrho has been used. It recognizes a protein on the surface of red cells and essentially ties up the reticuloendothelial system. But it causes a mild anemia, so has fallen out of favor. Steroids, rituximab, splenectomy, and thrombopoietin agonists r options. ...Read more

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Is itp a form of cancer? Since they found out that I have low platelets in 07. I heaven on IV treatments. My platelets can be 168 an still taktreatment

Is itp a form of cancer? Since they found out that I have low platelets in 07. I heaven on IV treatments. My platelets can be 168 an still taktreatment

No: Ttp is a disorder causing clot formation in microscopic blood vessels and resulting in low platelet counts altered mental status and renal failure. It responds to plasmapheresis. Cause is unknown. Some forms of cancer may be complicated by ttp and there is a genetic form too. ...Read more

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I have chronic itp since I was 14. How do I get cured?

Good question: What treatments have you had? The medical treatments have typically included steroids, other immunosuppressive medications, rituximab. These medications do not always work, and sometimes they only work temporarily. The main surgical treatment is splenectomy. This does not always work either. The goal is to keep you platelets high enough so that you are not having frequent bleeding. Good luck. ...Read more

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If a mother is pregnant and gets itp while pregnant, does the baby contract this disease at the same time?

Passive transfer can: Unfortunately, the maternal antibodies are usually of the IgG class and can cross the placenta, more commonly in very late pregnancy. If this does occur it is of short duration, since the child makes no platelet antibodies. It is not severe for most, if it does occur. ...Read more

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Biggest pregnancy risk fron itp?

Bleeding: Itp is low platelets without a clear reason for having them. For most women with itp, the platelets are low but still function well. If they get low enough though, there may not be enough to prevent significant bleeding related to surgery or delivery. Some women with low platelets will not be able to get an epidural. Sometimes antibodies in the mom will also cause bleeding problems in the baby. ...Read more

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How could one catch itp?

You don't: One does not catch itp. One develops it or acquires it. In children commonly a result of a viral infection. In adults, now referred to as immune thrombocytopenic purpura. Thought to be to increased destruction as well as underproduction of platelets. Hope this helps. ...Read more

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What are the tests for itp?

ITP: Thrombocytopenia or low platelet level can be caused by so many things such as drugs, platelet consumption by clots, infections, vitamin deficiency, cancer related etc. Your doctor has to rule out all those possibilities and ultimately to do a bone marrow biopsy to eval bone marrow. See your md and discuss further re-diagnosis approach/treatment and other things you need to know re - itp. ...Read more

See 2 more doctor answers
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What are the symptoms of itp?

Symptom: Most of the time itp patients are asymptomatic and the only abnormality they have is the low platelet level on their blood counts. They can have bruising, tiny red dots on the skin, roof of the mouth etc- (ptechiae) or other type of bleeding such as bleeding in the gum, only if platelet level goes down really low-below 30k or so. ...Read more

See 2 more doctor answers