Doctor insights on:
Itching Kidney Failure Multiple Myeloma
I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
Labs, xrays: There are a series of blood and urine tests that will give the doctor a good idea if you have the disease. These are usually followed by x-rays looking for tell-tale signs of myeloma and a bone marrow test which would identify the cancer cells themselves. ...Read moreSee 1 more doctor answer
My brother (51) is in the final stages of multiple myeloma and was told he will die of kidney failure. Blood tranfusions weekly. Timeline estimate?
Get extra support: Agree with prior answer that difficult to say. If not already involved ask for a palliative medicine specialist to work with your hematology-oncology team. They might be able to provide additional prognostication opinions as they monitor his progress and also provide additional support for the time that he has. ...Read moreSee 1 more doctor answer
Kidney biopsy shows the reason for kidney failure is multiple myeloma. No bone damage, hemo. More than 12. Will kimo therapy help to recover fully?
Seek opinion from a: This is unusual way to make a diagnosis of multiple myeloma(mm). Typically we need to do a bone marrow biopsy and look for cancer cells in the marrow. These cells produce abnormal proteins(m protein) which will show up either in the blood(commonly) or in the urine. We use a test called protein electrophoresis. If these tests have not been done, seek a second opinion. Chemo will help to control mm. ...Read more
I seriously doubt it: I cannot say I have ever seen a patient with this association. ...Read more
Depends: This can best be answered by your treating physician. It often depends on age, other medical disorders, previous treatments, response to velcade (bortezomib). Most patients will have improvement in renal failure if this is the first treatment they receive, and the treatment usually includes velcade (bortezomib). ...Read more
Why sickle cell anemeia / multiple myeloma cause diabetes insipidus ? Is it because it may obstruct the blood flow to the kidneys and damage them?
Basically right: Even sickle cell trait ruins much of the concentrating ability of the kidneys by adulthood. Myeloma is more likely to damage and obstruct the tubules themselves. Both produce a kidney lesion that prevents the urine from becoming concentrated, rather than a pituitary diabetes insipidus. ...Read more
I have Multiple Myeloma & I'm hypocellular I have been offered steroid injection for pain is it safe?
Steroid is treatment: Steroids are part of the standard treatment of myeloma. Usually the steroid (typically dexamethasone) is administered with another agent. It is usually administered by mouth. It's not clear what your pain is or what kind of injection is proposed. ...Read moreSee 1 more doctor answer
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
A condition in which your kidneys suddenly stop working normally. Since your kidneys remove waste products and help balance water and salt and other minerals (electrolytes) in your blood, when your kidneys stop working, waste products, fluids, and electrolytes build up in your body. This can cause problems ...Read more