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Doctor insights on: Isradipine

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Dr. Robert Messing
30 doctors shared insights

Isradipine (Overview)

Isradipine is a diabetes-related agent which is a kind of nutritional or metabolic agent.


Dr. Robert Messing
30 doctors shared insights

Isradipine (Overview)

Isradipine is a diabetes-related agent which is a kind of nutritional or metabolic agent.


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Has anybody prescribed isradipine for Parkinson's disease?

Has anybody prescribed isradipine for Parkinson's disease?

Yes, but for HTN : In other words, if you have pd & htn, why not use it? Isradipine is a calcium-channel blocker used to treat hypertension. But, it was found in dopamine-producing neuron cell cultures to help extend survival of the neurons by reducing calcium influx--a sinister, universal late stage process during programmed cell death (apoptosis) in parkinson's disease & other neurodegenerative disorders. ...Read more

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How is isradipine use for Parkinson's disease?

How is  isradipine use for Parkinson's disease?

?Can it slow disease: Isradipine is a calcium-channel blocker used to treat hypertension. But, it was found in dopamine-producing neuron cell cultures to help extend survival of the neurons by reducing calcium influx--a sinister, universal late stage process during programmed cell death (apoptosis) in parkinson's disease & other neurodegenerative disorders. ...Read more

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Why was dynacirc (isradipine) discontinued in us?

Why was dynacirc (isradipine) discontinued in us?

FDA compliance: Novartis shut down the lincoln nebraska plant that packages Dynacirc (isradipine) after recalling almost 400, 000 bottles due to fda cited compliance concerns. There had been repeated poor inspection findings by the fda. I don’t know if the plant will reopen in the summer of 2013 or not. ...Read more

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How is isradipine use for Parkinson's disease?

?Can it slow disease: Isradipine is a calcium-channel blocker used to treat hypertension. But, it was found in dopamine-producing neuron cell cultures to help extend survival of the neurons by reducing calcium influx--a sinister, universal late stage process during programmed cell death (apoptosis) in parkinson's disease & other neurodegenerative disorders. ...Read more

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Has anybody prescribed isradipine for Parkinson's disease?

Yes, but for HTN : In other words, if you have pd & htn, why not use it? Isradipine is a calcium-channel blocker used to treat hypertension. But, it was found in dopamine-producing neuron cell cultures to help extend survival of the neurons by reducing calcium influx--a sinister, universal late stage process during programmed cell death (apoptosis) in parkinson's disease & other neurodegenerative disorders. ...Read more

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I take both isradipine and losartan for hbp. Previously was prescribed nefidipine which caused swollen ankles. Still have swollen ankles. What?

I take both isradipine and losartan for hbp.  Previously was prescribed nefidipine which caused swollen ankles.  Still have swollen ankles.  What?

Isradipine: Isradipine is similar to Nifedipine so the swollen ankles aren't a surprise if the Nifedipine was the cause. A different agent or a trial of support hose may help. ...Read more

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I started symptoms of parkinsons.Loss of smell almost total now.Ridgity and loss of balence has gotten worse.Would isradipine help.Sinemet (carbidopa and levodopa) helped .?

I started symptoms of parkinsons.Loss of smell almost total now.Ridgity and loss of balence has gotten worse.Would isradipine help.Sinemet (carbidopa and levodopa) helped .?

Maybe, see below.: Isradipine has had some small studies that suggest it might be helpful, but we really don't know. There are many other medicines out there that are fda approved that will help more. Sinemet as you mentioned is one. Other medicines include the Dopamine imposters such as mirapex, requip, and neupro (rotigotine). I would recommend one of these before trying isradipine, which may not do much symptomatically. ...Read more

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Dr. Tiffanie Noonan
6 doctors shared insights

Dynacirc (Definition)

DynaCirc is a diabetes-related agent which is a kind of ...Read more