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Doctor insights on: Isotretinoin Side Effects

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Isotretinoin -- any bad side effects?

Isotretinoin -- any bad side effects?

Potentially: Can cause depression, change in sleep or mood, sudden numbness or weakness on one side of the body, changes in vision, hearing, seizures, pain in stomach, severe diarrhea, flu-like symptoms, joint or bone aches, severe rash. There are other minor side effects. You should discuss this with the doctor before ever taking the medication. ...Read more

Dr. Kristi Woods
318 doctors shared insights

Isotretinoin (Definition)

More commonly known as accutane, Isotretinoin is an oral medication that is incredibly effective for severe acne. It is especially useful to bring a halt to acne that is causing scarring. Isotretinoin has a variety of side effects including birth defects, liver damage, and problems with cholesterol, and careful monitoring ...Read more


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Why do dermatologists support the use of isotretinoin despite the controversial side effects it allegedly causes (depression, suicide ideation...)?

Why do dermatologists support the use of isotretinoin despite the controversial side effects it allegedly causes (depression, suicide ideation...)?

Causaility unclear: There is some controversy on this topic. There is some data showing an actual reduced rate of suicidal acts in patients treated when compared to the control cohort (age/demographics) who are not treated with this medicine. Case reports and anecdote are important, but eventually the science has to be done to dissociate correlation / association versus causality. ...Read more

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How severe are the side effects of using isotretinoin?

How severe are the side effects of using isotretinoin?

Isotretinoin: The most common side effects are dry mucous membranes, photosensitivity, major birth defects and joint pain. Rare serious side effects include: pseudotumor cerebri, premature epiphyseal closure, pancreatitis, psychosis, anemia, suicidality, visual disturbance, hepatoxicity, aggression and others. Blood work is drawn every month and if side effects occur the med is stopped. ...Read more

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I have been prescribed isotretinoin 20mg for a month. Afraid of its side effects. How much usage will cause the side effects?

Every patient differ: It is hard to know. Every patient differs. The dose you are taking is in the usual range. The dose or the length of treatment may effect what potential side effects you might have. ...Read more

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What are the side effects does isotretinoin carry?

Lots: A few common: itching, nosebleeds, muscle aches, headache, elevated liver enzymes, elevated lipids, ringing in the ears. Major: increased pressure in the head, bone problems, liver toxicity, severe rash, behavior changes, hearing problems, visual disturbances, anemia, kidney problems, and severe birth defects if taken during pregnancy, especially early on. It is not a first line acne treatment. ...Read more

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What are the most frequently reported side- effects of Isotretinoin (Roaccutane) that persisted after its discontinuation?

None: Most prominent side effect is dry skin, especially lips. After a week there are no side effects. There are POSITIVE side effects persisting after it is stopped. There is little or no acne and there is an improved mood after a full course. ...Read more

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Question about side effects of isotretinoin (accutane) for a male?

Question about side effects of isotretinoin (accutane) for a male?

Can you be specific?: There are numerous side effects that can occur for people taking isotretinoin. Most commonly, dryness and increased sun sensitivity, seem to affect nearly everyone. As far as the other side effects, they are uncommon. You will have to be more specific. ...Read more

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Are my fears of going on isotretinoin irrational? i have read that it can cause permanent side effects even after discontinuation

Are my fears of going on isotretinoin irrational? i have read that it can cause permanent side effects even after discontinuation

No, they're not: More people should have concerns about side effects of medications, no matter what the medicine. Only then can you make an informed decision about using it vs. not. Your med works fantastic against acne. But yes, there are potential serious side effects. Properly monitored by a good dermatologist, med can be stopped if these occur before permanent damage. Question is - are you willing to risk it? ...Read more

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Can you take diet pills while on isotretinoin (40mg pills once a day)? Will one cancel out the other or even cause bad side effects?

Can you take diet pills while on isotretinoin (40mg pills once a day)? Will one cancel out the other or even cause bad side effects?

Sure. But wise? No!: Look it up, e.g. Search google "isotretinoin 40mg nih". Next, do safe & effective diet pills exist? No! by law, dshea 1994, see fda.Gov, for dietary supplements sold otc, the marketers are exempt from evaluating & proving their claims. Victoza (liraglutide) & symlin, fda approved for diabetes (not wt. Loss per-se), are helpful for wt ?. Best cut the carbs, study nusi.Org, “sugar: the bitter truth” & exercise. ...Read more