Doctor insights on:
Isosorbide Mononitrate Vs Dinitrate
How long they last: The main difference is how long they last. Most dinitrate products are designed to be taken at least 2 x a day where as most of the mononitrate products once a day. They both are quite effective at controlling angina when appropriately prescribed. Some side effects thought a bit less with mono v. Di, but that varies a lot from person to person.
You should take: Whichever your health care provider has recommended. Mononitrate has a longer half life and less likely to develop tolerance. Used more commonly in stable angina patients. Ask your health care provider this questions as s/he has your medical history available.
Isosorbide mononitrate extended-release (imdur) vs quick acting release (by kremers). Which one can develop tolerance more. Which one prescribed often?
Different targets: Either can develop tolerance, long acting a little more likely b/c in system longer. But imdur usually for prolonged venous-dilitation / cardiac perfusion effects and immediate / short formulation more common w/cardiac symptoms. Ask you cardiologist or pharmacist for more specific information.
That's ok: Okay to do so but would make sure this is done under physician advice.
Can you tell me how much time after ceasing dosage of isosorbide mononitrate does it take to clear your system?
Isosorbide mononitra: The half time is about 5hrs, it should be substantially gone at 24hrs.
Does monoket or its genric isosorbide mononitrate come as extended release or just immediate release. What are the different strengths.
Monoket: Also known as imdur comes in 30 60 and 120 mg it is a once a day drug but some docs like myself will use it twice a day.
Cardiologist wrote 10 mg. Pharmacy has only 20 mg. Can you split isosorbide mononitrate 20 mg (monoket brand name). Is this extended release? Thanks.
Yes: Yes you can split the tab.Get a more detailed answer ›
Isosorbide mononitrate is causing itching for my mother after having cardiac catheterization and prescribed to her, is it normall? If not alternatives?
Itching: The itching is more likely to be related to the contrast used during angiography. It is much less likely to have itching related to isosorbide.
Can using 0.3ml lidocaine with 1:100, 000 epinephrine during dental work interacts with bystolic, (nebivolol) benicar/hct or isosorbide mononitrate medicine.?
Probably not: Although Lidocaine is a vasodilator, there is no clinical evidence of any drug interactions or special precautions needed. However, if during the injection, some of the anesthetic were to be introduced directly into a blood vessel, the Epinephrine could cause a minor and short acting increase in heart rate.See 2 more doctor answers
I'm taking 45mg isosorbide mononitrate ER for coronary artery spasms 25mg metoprolol ER for high bp. Will I have to be on these the rest of my life?
Maybe (not). . .: You'll need to address this question w/your cardiologist & family doc. If you're overweight or obese, it's possible to come off blood pressure, cholesterol & diabetes medications by changing lifestyle, eating right, exercising regularly & losing weight. Just curious, but why didn't you mention Lisinopril in your question? Regardless, metoprolol & Isosorbide Mononitrate can help decrease spasm.
Supply and demand: Angina is caused by heart muscle not getting enough blood to meet its needs, think supply vs demand. By relaxing smooth muscle in the walls of coronary arteries, nitrates increase blood flow. They also dilate the body's veins, so less blood returns to the heart, and the heart walls are less stretched outwards. This reduces tension on the heart wall muscle, and hence demand for oxygen/blood.See 1 more doctor answer
Does prolonged usage of isosorbide mono nitrate (ismo) cause vertigo and dizziness? Please, need some answers?
No: No it doesn't. There's your answer.Get a more detailed answer ›
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