Top
20
Doctor insights on: Isosorbide Mononitrate Vs Dinitrate

Share
1

1
What's the difference between isosorbide mononitrate vs isosorbide dinitrate?

What's the difference between isosorbide mononitrate vs isosorbide dinitrate?

How long they last: The main difference is how long they last. Most dinitrate products are designed to be taken at least 2 x a day where as most of the mononitrate products once a day. They both are quite effective at controlling angina when appropriately prescribed. Some side effects thought a bit less with mono v. Di, but that varies a lot from person to person.

Dr. Brad Goldenberg
36 Doctors shared insights

Isosorbide Mononitrate (Definition)

Isosorbide mononitrate is a nitrate based agent which is a kind of chest ...Read more


2

2
Should I take isosorbide dinitrate or isosorbide mononitrate?

Should I take isosorbide dinitrate or isosorbide mononitrate?

You should take: Whichever your health care provider has recommended. Mononitrate has a longer half life and less likely to develop tolerance. Used more commonly in stable angina patients. Ask your health care provider this questions as s/he has your medical history available.

5

5
Isosorbide mononitrate extended-release (imdur) vs quick acting release (by kremers). Which one can develop tolerance more. Which one prescribed often?

Isosorbide mononitrate extended-release (imdur) vs quick acting release (by kremers). Which one can develop tolerance more. Which one prescribed often?

Different targets: Either can develop tolerance, long acting a little more likely b/c in system longer. But imdur usually for prolonged venous-dilitation / cardiac perfusion effects and immediate / short formulation more common w/cardiac symptoms. Ask you cardiologist or pharmacist for more specific information.

6

6
What is isosorbide mononitrate used for?

What is isosorbide mononitrate used for?

To treat heart Dx.: It is a longer acting nitrate to vasodilate coronary arteries if a patient has exertional angina.

7

7
What will happen if I overdose on isosorbide mononitrate?

What will happen if I overdose on isosorbide mononitrate?

Various: If you are talking about accidentally taking an extra dose, you should expect a headache, and possibly some dizziness from your blood pressure dropping.

15

15
Isosorbide mononitrate is causing itching for my mother after having cardiac catheterization and prescribed to her, is it normall? If not alternatives?

Isosorbide mononitrate is causing itching for my mother after having cardiac catheterization and prescribed to her, is it normall? If not alternatives?

Itching: The itching is more likely to be related to the contrast used during angiography. It is much less likely to have itching related to isosorbide.

16

16
Can using 0.3ml lidocaine with 1:100, 000 epinephrine during dental work interacts with bystolic, (nebivolol) benicar/hct or isosorbide mononitrate medicine.?

Probably not: Although Lidocaine is a vasodilator, there is no clinical evidence of any drug interactions or special precautions needed. However, if during the injection, some of the anesthetic were to be introduced directly into a blood vessel, the Epinephrine could cause a minor and short acting increase in heart rate.

See 2 more doctor answers
17

17
I'm taking 45mg isosorbide mononitrate ER for coronary artery spasms 25mg metoprolol ER for high bp. Will I have to be on these the rest of my life?

I'm taking 45mg isosorbide mononitrate ER for coronary artery spasms 25mg metoprolol ER for high bp. Will I have to be on these the rest of my life?

Maybe (not). . .: You'll need to address this question w/your cardiologist & family doc. If you're overweight or obese, it's possible to come off blood pressure, cholesterol & diabetes medications by changing lifestyle, eating right, exercising regularly & losing weight. Just curious, but why didn't you mention Lisinopril in your question? Regardless, metoprolol & Isosorbide Mononitrate can help decrease spasm.

18

18
How does isosorbide dinitrate or mononitrate help prevent angina attacks?

How does isosorbide dinitrate or mononitrate help prevent angina attacks?

Supply and demand: Angina is caused by heart muscle not getting enough blood to meet its needs, think supply vs demand. By relaxing smooth muscle in the walls of coronary arteries, nitrates increase blood flow. They also dilate the body's veins, so less blood returns to the heart, and the heart walls are less stretched outwards. This reduces tension on the heart wall muscle, and hence demand for oxygen/blood.

See 1 more doctor answer
Dr. Ana Adelstein
15 Doctors shared insights

Monoket (Definition)

Monoket is a nitrate based agent which is a kind of chest ...Read more


Dr. Mark Ingerman
36 Doctors shared insights

Imdur (Definition)

Imdur is a nitrate based agent which is a kind of chest ...Read more