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Doctor insights on: Isordil

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Dr. Gregory Moneta
17 doctors shared insights

Isordil (Overview)

Isordil is a nitrate based agent which is a kind of chest pain drug (cardiovascular drug).


Dr. Gregory Moneta
17 doctors shared insights

Isordil (Overview)

Isordil is a nitrate based agent which is a kind of chest pain drug (cardiovascular drug).


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In a patient with migraines, will their frequency increase if the patient takes isordil (isosorbide dinitrate)?

In a patient with migraines, will their frequency increase if the patient takes isordil (isosorbide dinitrate)?

Isordil (isosorbide dinitrate) & Headaches: Isordil is nitroglycerine, a vasodilator for the heart( seldom other) which can cause headaches. It is dose dependent, the higher the most likely headache. You may take tylenol (acetaminophen) for it. If your migraines get worst talk to the cardiologist about it. ...Read more

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What is isosorbide dinitrate?

What is isosorbide dinitrate?

Isosorbide dinitrate: Iosorbide dinitrate is a medication used to treat/ prevent angina. ...Read more

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Who should not use isosorbide dinitrate?

Isosorbide dinitrate: "Allergic reactions to organic nitrates are extremely rare, but they do occur. The isosorbide dinitrate tablet is contraindicated in patients who are allergic to ISDN or any of its other ingredients." See: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8bb91825-b63e-44aa-8edd-4326823f3009 ...Read more

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What are some of the disadvantages by using isosorbide dinitrate?

Minor: Some people have issues with headaches or low blood pressure. Both of these resolve if the medication is stopped. ...Read more

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Could you explain what is isosorbide dinitrate (isoket spray) ?

Could you explain what is isosorbide dinitrate (isoket spray) ?

RU in the UK?: Isoket spray is not available in the usa . It's a form of Nitroglycerin and it's used under the tongue for rapid relief of angina spells. In the usa, we use Nitroglycerin as a tablet or a spray and we use Isosorbide Dinitrate tablets for longer lasting relief/prophylaxis of angina. ...Read more

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How does isosorbide dinitrate or mononitrate help prevent angina attacks?

How does isosorbide dinitrate or mononitrate help prevent angina attacks?

Supply and demand: Angina is caused by heart muscle not getting enough blood to meet its needs, think supply vs demand. By relaxing smooth muscle in the walls of coronary arteries, nitrates increase blood flow. They also dilate the body's veins, so less blood returns to the heart, and the heart walls are less stretched outwards. This reduces tension on the heart wall muscle, and hence demand for oxygen/blood. ...Read more

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Should i take isosorbide dinitrate or isosorbide mononitrate?

You should take: whichever your health care provider has recommended. Mononitrate has a longer half life and less likely to develop tolerance. Used more commonly in stable angina patients. Ask your health care provider this questions as s/he has your medical history available. ...Read more

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Whats the difference between isosorbide mononitrate vs isosorbide dinitrate?

How long they last: The main difference is how long they last. Most dinitrate products are designed to be taken at least 2 x a day where as most of the mononitrate products once a day. They both are quite effective at controlling angina when appropriately prescribed. Some side effects thought a bit less with mono v. Di, but that varies a lot from person to person. ...Read more

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How does isosorbide dinitrate and hydralazine work in treating congestive heart failure?

How does isosorbide dinitrate and hydralazine work in treating congestive heart failure?

A-HEFT Trial: A large trial looked at the combination of hydralazien and Isordil (isosorbide dinitrate) with african american patients and showed a benefit of improving heart failure status, on top of standard medical therapy. It is thought to be believed due to lack of Nitric Oxide delivery to endothelium in african americans, that is improved by this therapy. Blood pressure tends to be higher in the first place, which improves. ...Read more

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To control CHF is it normal to prescribe hydralazine alone or with isosorbide dinitrate? she has no hypertension, but AF. headache+AF worsens wt these

To control CHF is it normal to prescribe hydralazine alone or with isosorbide dinitrate? she has no hypertension, but AF. headache+AF worsens wt these

Yes: The combination of hydralazine and isosorbide reduce filling pressures in the heart, reduce the amt of work the heart must do, & reduce the changes in structure to the heart that heart failure brings. This is for heart failure where the ejection fraction is less than 40%. ...Read more

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How effective is isosorbide dinitrate for treating coronary artery disease (CAD)?

Isosorbide dinitrate: Iosorbide dinitrate is beneficial in the treatment & prevention of angina. ...Read more

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If you are feeling these side affect numbness tingling of hands legs and feet from taken carvedilol isosorbide dinitrate and hydralazine?

If you are feeling these side affect numbness tingling of hands legs and feet from taken carvedilol isosorbide dinitrate and hydralazine?

Antihypertensives: The medications above are used to treat high blood pressure. They are usually tolerated well but uncommonly do have side effects. New onset numbness and tingling has many causes and isn't necessarily related to your medications. ...Read more

Dr. Gregory Moneta
20 doctors shared insights

Isosorbide Dinitrate (Definition)

Isosorbide dinitrate is a nitrate based agent which is a kind of chest ...Read more