Top
30
Doctor insights on: Isoniazid Allergy In Children

Share
1

1
What is the definition or description of: Isoniazid allergy?

What is the definition or description of: Isoniazid allergy?

Isoniazid allergy: Isoniazid (isonicotinylhydrazide or INH) is an antibiotic that is used in the treatment of tuberculosis. Medication allergic reactions can include difficulty breathing, hives and swelling of face, lips, throat, mouth or tongue. ...Read more

Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


2

2
Does isoniazid causes blood problems?

Does isoniazid causes blood problems?

See below:: Isoniazid may cause severe and sometimes fatal liver damage. Tell your doctor if you have or have ever had liver disease or a history of alcoholism or injection drug use. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to isoniazid. ...Read more

3

3
Does isoniazid causes hematologic dysfunction?

Does isoniazid causes hematologic dysfunction?

Yes: Isoniazid causes many adverse reactions. Hepatitis is the most feared. It also can cause peripheral neuropathy, fever, skin rashes and hematologic abnormalities among others. ...Read more

4

4
Do I still have tuberculosus if I took isoniazid for a year?

Do I still have tuberculosus if I took isoniazid for a year?

Probably not: Treatment of latent tuberculosis infection with 9-12 months of daily Isoniazid (assuming excellent adherence) is 80-90% effective in eliminating the latent infection. ...Read more

5

5
Why is isoniazid is prescribed for latent tb?

Why is isoniazid is prescribed for latent tb?

See below:: Isoniazid is used alone or with other drugs to treat tuberculosis (TB) and to prevent it in people who have had contact with tuberculosis bacteria. It eliminates only active (growing) bacteria. Since the bacteria may exist in a resting (nongrowing) state for long periods, therapy with Isoniazid (and other antituberculosis drugs) must be continued for a long time (usually 6-12 months). ...Read more

6

6
Should I be worried I missed 2 doses of isoniazid for tb?

Should I be worried I missed 2 doses of isoniazid for tb?

Missed isoniazid: No, missing only 2 doses of inh would not be a problem. Tb is very slow growing, so missing 2 doses wouldn't be enough time for it to recover and start growing again. ...Read more

7

7
Help! Really worried? I missed 2 doses of isoniazid for tb?

Isoniazid: "Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication." REF: http://www. Rxlist. Com/isoniazid-tablets-drug/patient-images-side-effects. Htm#missdose ...Read more

8

8
Has anyone shown that isoniazid (inh) causes diabetes mellitus?

Has anyone shown that isoniazid (inh) causes diabetes mellitus?

No: While isoniazid is associated with rise in in blood sugar as a side effect, that's a temporary effect - and *not* the same as saying that it causes diabetes, which is very different than saying a person has diabetes, where a person is no longer able to process sugar properly. There are no literature or data showing that isoniazid directly causes people to develop the disease of diabetes. ...Read more

12

12
Is isoniazid and alcohol safe to take together?

Is isoniazid and alcohol safe to take together?

Moderation: Alcohol in reasonable amounts is ok in patients on inh. Both can be hepatotoxic but a glass of wine or a beer is ok. ...Read more

13

13
How significant is the risk of drinking when taking isoniazid?

How significant is the risk of drinking when taking isoniazid?

Fairly significant!: Age appeares to be the predominant factor influencing the risk of developing isoniazid-related hepatitis (increasing age is associated with an increasing risk). Drinking alcohol, especially on a daily basis, enhances the risk of hepatitis among those taking isoniazid. Weighing the benefits of Isoniazid in preventing tuberculosis against the risk of its causing hepatitis nec. F/u with your doctor. ...Read more

14

14
What do you advise if I'm taking rifampicin& isoniazid tablet?

What do you advise if I'm taking rifampicin& isoniazid tablet?

Rifampicin/isoniazid: Here are recommendations from Mayo Clinic: http://www. Mayoclinic. Org/drugs-supplements/rifampin-and-isoniazid-oral-route/precautions/drg-20062747 ...Read more

15

15
If you had sex and you are taking isoniazid is there any concern?

If you had sex and you are taking isoniazid is there any concern?

No: Main concern will be whether patient remain compliant with recommended treatment plan. ...Read more

16

16
Why can't you drink alcoholic bevareges when you are taking isoniazid?

Why can't you drink alcoholic bevareges when you are taking isoniazid?

INH hepatitis: Isoniazid (inh) can cause liver damage, and so can alcohol. Drinking alcohol increases the risk of inh hepatitis. ...Read more

18

18
What reactions can Overuse (very long duration) use of INH (isoniazid) cause in the body? Does it do the opposite like cause fungal overgrowth?

What reactions can Overuse (very long duration) use of INH (isoniazid) cause in the body? Does it do the opposite like cause fungal overgrowth?

INH is fairly safe d: It is a relatively safe drug. Its one toxicity of concern is a mild hepatitis which, fortunately is relatively uncommon. There is no risk of fungal infections. You should not take it for any more than one year maximum. If you have taken it for one year, you should be able to stop it after speaking with your treating physician. ...Read more

19

19
How will my prescription isoniazid affect consumption of alcohol?

Don't drink: Ideally it will cause you to stop drinking while you're taking it, but that's up to you. Alcohol increase the risk of inh hepatitis. ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
20

20
Is there a significant risk of drinking alcohol when taking isoniazid?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Is there a significant risk of drinking alcohol when taking isoniazid?

Alcohol: Not good idea to mix alcohol with any medication metabolized by liver. ...Read more

22

22
Why doctors consider drugs like (rifampicin & isoniazid) as risk factor of metabolic syndrome?

Why doctors consider drugs like (rifampicin & isoniazid) as risk factor of metabolic syndrome?

Metab syndrome: An insulin-sensitizing agent, such as metformin, is often used as hyperglycemia treatment in patients with metabolic syndrome. Literature suggests that metformin may help to reverse the pathophysiologic changes of metabolic syndrome. Cannot find any evidence that Rifampin is a risk factor for metabolic syndrome. ...Read more

23

23
Quantaferon Gold +, had 9 months Isoniazid & Pyrazinoide. Do I still need chest x-rays every two years?

Quantaferon Gold +, had 9 months Isoniazid & Pyrazinoide. Do I still need chest x-rays every two years?

When it comes to: TB - I would follow medical directives exactly. Tuberculosis is nothing to fool around with. I see that you are a first year medical student. When you get into clinical work- you will understand the need for strict compliance when it comes to TB. ...Read more

24

24
Do refampicin and isoniazid decrease vitamin b6?

Do refampicin and isoniazid decrease vitamin b6?

See below: Isoniazid neuropathy develops in the presence of risk factors (hiv, alcoholism, diabetes, renal failure, malnutrition, pregnancy and lactation, neurotoxic medication) and manifests itself initially by burning feet. Your doctor may also want you to take a supplemental vitamin b6 (pyridoxine) tablet daily during treatment to prevent numbness and tingling caused by low levels of this vitamin. ...Read more

25

25
Is isoniazid, pyrazinamide, and rifampin safe in pregnancy?

Some risk: Isoniazid/pyrazinamide/rifampin are usually used in combination to treat tuberculosis. While tuberculosis is uncommon in pregnancy, these drugs may be appropriate to use for a pregnant women with confirmed tuberculosis. Breast feeding should not be done while taking these medications. ...Read more

26

26
What are the effects of inh (isoniazid) on my body if taken for 9 months?

What are the effects of inh (isoniazid) on my body if taken for 9 months?

Liver and nerve: Can cause liver problems and nerve problems (neuropathy) like numbness and tingling. Need to monitor these things. ...Read more

Dr. Jay Park Dr. Park
1 doctor agreed:
27

27
What are the effects of taking both rifampicin and isoniazid?

Dr. Jay Park Dr. Park
1 doctor agreed:
What are the effects of taking both rifampicin and isoniazid?

Synergistic effect: Latent tuberculosis has been treated for 10 months with Isoniazid alone. In several european countries, 3 months of daily Isoniazid and Rifampin are used to treat latent TB infection with apparent success. ...Read more

28

28
Can I start drinking again immediately after finishing isoniazid?

Can I start drinking again immediately after finishing isoniazid?

Wait a bit...: Isoniazid and alcohol consumption is associated with severe and sometimes fatal hepatitis that may occur during and many months after treatment. Risk is related to age and increased with daily alcohol consumption. ...Read more

30

30
My ALT is 142, probably caused by isoniazid. I have taken it for 50 days. Is it a serious issue? Do you think I should stop taking it immediately.

My ALT is 142, probably caused by isoniazid. I have taken it for 50 days. Is it a serious issue? Do you think I should stop taking it immediately.

No. Don't stop just: Isoniazid for a positive TB tine test or gamma interferon assay in the blood (I'm assuming here). We call that Latent TB. Its important to have a doctor monitoring your liver enzymes during this time. While it may seem that 142 is high. Its only about 3x normal. As long as your asymptomatic and it doesn't go any higher you should be fine. The standard is 6 months of INH then your done. ...Read more

Isoniazid Allergy (Definition)

Isoniazid (isonicotinylhydrazide or INH) is an antibiotic that is used in the treatment of tuberculosis. Medication allergic reactions can include difficulty breathing, hives and swelling of face, lips, ...Read more