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Doctor insights on: Islet Glutamic Ia 2 Cpep Insulin Autoantibodies

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What would cause an intolerance to glutamic acid? Gad autoantibodies? Gad deficiency? Glutamate receptor autoantibodies(anti-nmda, anti-ampa)?

What would cause an intolerance to glutamic acid? Gad autoantibodies?  Gad deficiency?  Glutamate receptor autoantibodies(anti-nmda, anti-ampa)?

None of the above.: Msg - ubiquitous Amino Acid and major excitatory neurotransmitter in brain. Studied extensively. Does not cause allergy or intolerance except at high dose and only then in susceptible persons when given in large doses without food. See fda, j. Nutrition, food chem and toxicology, etc. ...Read more

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Dr. Hunter Handsfield
123 doctors shared insights

Hsv Type 1 And 2 (Definition)

A variety of infections caused by herpes simplex virus types 1 and 2. Type 1 infections are marked by the eruption of vesicles on lips or at the external nares; type 2 by such lesions on the genitalia. Both types often are dormant and reappear during febrile illnesses or even physiologic states such as menstruation. The viruses become latent and and may not ...Read more


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Can glutamic acid decarboxylase antibody be reduced in the body?

Can glutamic acid decarboxylase antibody be reduced in the body?

Glutamic acid decarb: Not that I am aware of. There are two forms of this enzyme coincidentally and the antibody is felt to be an autoimmune response to predict Insulin requirement in early type one diabetics. ...Read more

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Does glutamic acid good for als?

Does glutamic acid good for als?

Not at all: Quite the reverse, as many recommended meds are designed to inhibit glutamate responses. Regardless, the sole approved drug, Riluzole merely delays intubation, and is otherwise disappointing. Do not look for alternative therapies, they do not exist here in this very discouraging disorder. ...Read more

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I get savage irrational rage & full-body dysesthesia when eating food high in aspartic, glutamic, & arachidonic acid. Why? Nmda receptor dysfunction?

I get savage irrational rage & full-body dysesthesia when eating food high in aspartic, glutamic, & arachidonic acid.  Why? Nmda receptor dysfunction?

MSG: We don't know. There is disagreement with such reactions but I have seen msg sensitivities and it can close to what you are describing. For more info go to http://inkchromatography.Wordpress.Com/2012/05/01/the-msg-files-part-iv-chinese-restaurant-syndrome-2/. ...Read more

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Why does l glutamic acid give me anxiety?

Why does l glutamic acid give me anxiety?

Excitatory: Glutamate molecule in the brain acts as an excitatory neurotransmitter, actually it is the most ubiquitous excitatory neurotransmitter in the brain.So it is possible this is how it leads to elevation of your anxiety. ...Read more

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I have a glutamic acid decarboxylase antibody level of 3.4 u/ml. Is this anything to worry about? Labcorp says the result is "high".

I have a glutamic acid decarboxylase antibody level of 3.4 u/ml.  Is this anything to worry about?  Labcorp says the result is "high".

Why ordered?: This is supposed to be a marker for a kid who's likely to get juvenile onset diabetes. Are you perhaps a newly-diagnosed diabetic? There's talk that elevated antibodies sort-of predicts that diabetes in an adult will behave more like type i diabetes (require insulin) than type ii, but i'm not aware of a consensus on whether there is a treatment guideline. Read up & ask for a clear answer. ...Read more

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If you have a glutamate metabolism disorder...& then you eat a food high in glutamic acid (meat, gluten, casein..Etc), what happens to you? Symptoms?

If you have a glutamate metabolism disorder...& then you eat a food high in glutamic acid (meat, gluten, casein..Etc), what happens to you? Symptoms?

A lot: Glutamate overall is an excitatory protein in the body. It stimulates the perception of taste and appetite. It also acts on the pancreas and liver. Our bodies need some but too much can cause a lot of different problems such as weight gain, diabetes, and neurotoxicity. In addition to avoiding high glutamate foods it is useful to consume extra carnitine (high in red meat) to counter the glutamate. ...Read more

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Glutamic acid decarboxylaxes antibodies results: 0.1 (u/mL) Ref range: 0.0 - 0.8 Meaning? Does it leads to stiff person syndrome?

Any symptoms?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, your result is in the normal range. Why was the test done? ...Read more

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L-glutamic acid gives me severe dysesthesias. D-glutamic acid is worse. Could I have glutamate metabolism disorder or glutamate receptor antibodies?

L-glutamic acid gives me severe dysesthesias. D-glutamic acid is worse.  Could I have glutamate metabolism disorder or glutamate receptor antibodies?

Possibly but...: Good question without an easy answer. Glutamate is an "excitotoxin" that is not healthy for anyone but some people are more sensitive to it than others. There are a variety of uncommon glutamate metabolism disorders but you do not need to have one of these to be adversely affected by glutamate. Dysesthesias are not a known symptom of antibodies to glutamate receptors. See my comments:. ...Read more

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I am 17 years old and I am consuming whey protein for last 2years should i continue to take whey protein which includes integedients like glutamine acid and glutamic is it safe for me to take whey protein continuous?

I am 17 years old and I am consuming whey protein for last 2years should i continue to take whey protein which includes integedients like glutamine acid and glutamic is it safe for me to take whey protein continuous?

SAFE: Yes, Whey protein is a safe/ healthy supplement when added to an already solid diet and exercise regimen. Whey protein contains easily digestible amino acids which can be quickly utilized by the body post work out to help rebuild muscle. The ratios of protein to calories and protein to fat in whey protein are far superior to most whole-food protein sources. Glutamine is an important amino acid. ...Read more

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Dear doctors,I'm a 18 years old and my bro 15 years old, is we safe to serve with whey protein contains BCAAs and glutamic acid?

Dear doctors,I'm a 18 years old and my bro 15 years old, is we safe to serve with whey protein contains BCAAs and glutamic acid?

Safe in moderation: BCAA and other protein foods etc are generally safe if used in moderation and not extended periods (6 months). Read the label carefully, manufacturer info . Check with doctor if you experience any symptom of fTigue cramps , abdominal pain or urinary problem etc. ...Read more

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Cystine is depleted, while glycine and glutamic acid are highly elevated. Does that mean cysteine and subsequent glutathione deficiency? Any ideas? Ty

Cystine is depleted, while glycine and glutamic acid are highly elevated. Does that mean cysteine and subsequent glutathione deficiency? Any ideas? Ty

Not useful tests tod: Why are you wasting your money doing tests which have no significant medical relavance? Find a good internist who can help you attain better health than you are suffering from by going off track. ...Read more

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Glutamic acid decarboxylaxes antibodies results: 0.1 (u/mL) Ref range: 0.0 - 0.8 test for spine leads to stiff person syndrome? HLA-B 1502 +

Glutamic acid decarboxylaxes antibodies results: 0.1 (u/mL)
Ref range: 0.0 - 0.8
test for spine
leads to stiff person syndrome?
HLA-B 1502 +

Not simple: Stiff Person is rare.
I advise use to visit with sub specialist, i.e. movement disorders neurologist, which likely are at University Hospital.
I had seen 2-3 cases over 15 years, and I always ask for second opinion from an expert.
...Read more

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Glutamic acid high, myoglobin low, pain in legs, swollen lymphs, ck spiked over 6500 then norm. Headaches and passed out and lots more. What is this?

Glutamic acid high, myoglobin low, pain in legs, swollen lymphs, ck spiked over 6500 then norm. Headaches and passed out and lots more. What is this?

Baclofen side effect: High levels of glutamic acid, specially the glutamic acid dedecarboxylase may be associated with auto immumne disease and type one diabeties.Myoglobinis a muscle protein found in all muscle tissues including the heart, it helps to carry oxygen to the muscle.High levels of CPK indicates some muscle damage wich is in contradiction with low myoglobine.Baclofen may produce the symptoms you are complning. ...Read more

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Taking cyclosporine and cellcept (mycophenolate mofetil) due to liver transplant, can I take SUKROL ( glutamic acid ), my memory and concentration been decreased lately. ?

Taking cyclosporine and cellcept (mycophenolate mofetil) due to liver transplant, can I take SUKROL ( glutamic acid ), my memory and concentration been decreased lately.    ?

Don't take it.: Sukrol is an OTC supplement containing multiple ingredients, including glutamic acid, lecithin, and thiamine. It is impossible to predict whether any of these could have an interaction with your cyclosporine or CellCept (mycophenolate mofetil). Given the potentially dire consequences of an interaction, it is not worth it to take your chances with an unproven supplement. Good luck. ...Read more

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Diagnosed with chronic fatigue, fibromyalgia and Hashimoto’s. Recently referred to metabolic clinic. Plasma Amino Acid Results: LOW Glutamic Acid, LOW Proline, and NO Hydroxyproline. Any recommendations for further tests, tx or diagnodid? Thank you.

Diagnosed with chronic fatigue, fibromyalgia and Hashimoto’s. Recently referred to metabolic clinic. Plasma Amino Acid Results: LOW Glutamic Acid, LOW Proline, and NO Hydroxyproline. Any recommendations for further tests, tx or diagnodid? Thank you.

Additional tests: I'm not sure if these have already been done but you could also get an allergen panel and testing for gluten insensitivity/celiac disease. Metabolic testing is probably the last area that's unexplored, which is usually the case in the scenario you're describing. Hope this helps ...Read more

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What is the difference between novolin (insulin) n and novolog for a type two diabetic?

What is the difference between novolin (insulin) n and novolog for a type two diabetic?

Onset/duration: Novolin n (a brand of nph) is an intermediate acting insulin. It starts working after a few hrs, peaks in 6-8 hrs and lasts 12-16 hrs. Novolog is a rapid acting insulin. It starts to work in a few mins, peaks in an hr or two, lasts 4 hrs or so. Novolog is used @meals to prevent post-meal high bs and to "correct" bs. Nph (or better yet a long acting like Lantus (insulin glargine) or levemir) keeps fasting bs lower. ...Read more

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Dr. Holly Maes
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24 Hour Urine Creatine (Definition)

A 24-hour urine collection is a simple diagnostic procedure that measures the components of urine. The test is noninvasive (the skin is not pierced), and is used to assess kidney (renal) function. Specifically the amount of creatinine excreted is measured to get an estimate of the ...Read more


Dr. Quang Nguyen
2,808 doctors shared insights

Insulin (Definition)

A hormone produced in the pancreas by the islets of langerhans that regulates the amount of ...Read more