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Doctor insights on: Islet Cell Carcinoma

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Dr. Sanjiv Kaul
2 doctors shared insights

Islet Cell Carcinoma (Overview)

Islet cell tumors of the pancreas represent the second form of lesion, the first representing lesions of ductal origin that lead to the classic pancreatic carcinoma, most frequently arising in the head. The second group of tumors, those of neuroendocrine origin arise in clustered cells known as islets and which are mainly benign When malignant they spread with a survival of about 5%


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I've developed islet cell carcinoma. What should I be watching out for in the future?

I've developed islet cell carcinoma. What should I be watching out for in the future?

Difficult to say: Islet cell tumors are rare forms of cancer that arise in the endocrine tissues of the pancreas. They can secrete a variety of hormones, including insulin, glucagon, gastrin, and vasoactive intestinal peptide, resulting in a myriad of clinical syndromes. However, the majority are not associated with a hormonal syndrome, and therefore, yours may have been detected incidentally. I need more info. ...Read more

Dr. Sanjiv Kaul
2 doctors shared insights

Islet Cell Carcinoma (Overview)

Islet cell tumors of the pancreas represent the second form of lesion, the first representing lesions of ductal origin that lead to the classic pancreatic carcinoma, most frequently arising in the head. The second group of tumors, those of neuroendocrine origin arise in clustered cells known as islets and which are mainly benign When malignant they spread with a survival of about 5%


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Are there any new treatment options for islet cell carcinoma?

Yes there are: Islet cell cancers are rare cancers. They are sometimes caught early and can be removed with surgery. This is the best treatment when possible. When they are metastatic, there are many medical treatments for them which can buy 5 to 10 years of life despite tumor being metastatic as they grow slowly(indolent tumors). ...Read more

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Living with Sickle Cell Disease (Checklist)

Don't miss appointments with your doctor
Once
Go to lab appointments as necessary
Once
Keep your oxygen levels up by maintaining a healthy weight
Once
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What is the definition or description of: Islet cell carcinoma?

What is the definition or description of: Islet cell carcinoma?

Pancreatic islets: Islet cell tumors of the pancreas represent the second form of lesion, the first representing lesions of ductal origin that lead to the classic pancreatic carcinoma, most frequently arising in the head.
The second group of tumors, those of neuroendocrine origin arise in clustered cells known as islets and which are mainly benign When malignant they spread with a survival of about 5% ...Read more

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I've developed islet cell carcinoma. What should I be watching out for in the future?

Difficult to say: Islet cell tumors are rare forms of cancer that arise in the endocrine tissues of the pancreas. They can secrete a variety of hormones, including insulin, glucagon, gastrin, and vasoactive intestinal peptide, resulting in a myriad of clinical syndromes. However, the majority are not associated with a hormonal syndrome, and therefore, yours may have been detected incidentally. I need more info. ...Read more

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Are there any new treatment options for islet cell carcinoma?

Yes there are: Islet cell cancers are rare cancers. They are sometimes caught early and can be removed with surgery. This is the best treatment when possible. When they are metastatic, there are many medical treatments for them which can buy 5 to 10 years of life despite tumor being metastatic as they grow slowly(indolent tumors). ...Read more

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What is an islet cell cancer?

What is an islet cell cancer?

Tumor of pancrease (pancrelipase): Islet cells are the cells located in the pancrease (pancrelipase) that make insulin. A tumor can form there from a degrading of the islet cell into an abnormal form and then cancerous. Hope this helps. ...Read more

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I have heriditary pancreatitis. Had islet cell done. 2 year out. My lym are high 5.26 WBC 12.7. Is this still within a ok range. I worry about cancer.

I have heriditary pancreatitis. Had islet cell done. 2 year out. My lym are high 5.26 WBC 12.7. Is this still within a ok range. I worry about cancer.

A rare inherited: Condition characterized recurrent episodes of acute pancreatitis. It can progress to chronic pancreatitis. Yes, there is a link to an increased lifetime risk of pancreatic cancer. Are you having any symptoms now? Any screening for cancer done? Like mri, ct scan, ercp, ultrasuound, ca-19-9 level. You should have a primary care physician following you and also a gastroenterologist that know you. ...Read more

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Found a lump on my l side rib cage in the middle, I have vhl a history of islet cell cancer of the pancreas both adrenals don't function, is this lump bad?

Have it checked: Neuroendocrince cancers can spread to unusual sites, including the bone. A familial cancer syndrome puts you are particular risk and i would have it evaluated. ...Read more

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What about neuroendocrine (islet cell tumors)?

What about neuroendocrine (islet cell tumors)?

Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting in weight & gain and low blood sugars. ...Read more

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Should i be concerned if my wife wants an islet cell transplant. What do you think?

Should i be concerned if my wife wants an islet cell transplant. What do you think?

Weigh the options: Islet cell transplants are performed, and many patients have been helped by them. In particular, to treat the terrible symptom of hypoglycemic unawareness. Like any surgical procedure there are risks and benefits that should be carefully discussed and understood before you go forward with the procedure. ...Read more

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Can you tell me how to find out if the islet cell transplant is for me, or if im eligable for it?

Evaluate carefully : You need to have a careful discussion of your degree of diabetes, and the risks and benefits of the procedure. Find a local transplant center that does the proceed and go over these issues point by point. Procedure itself, results short and long term, medications needed, their side effects, etc. Contact the american society of transplant surgeons for centers in your region. ...Read more

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Is the islet cell transplant a solution for those with chronic pancreatitis?

Is the islet cell transplant a solution for those with chronic pancreatitis?

Not at this time: Rx is to treat the diabetes (can be difficult), pain relief, supplemental enzymes, avoiding alcohol, sometimes surgery. ...Read more

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Does badal cell carcinoma itch?

Does badal cell carcinoma itch?

Yes it can: Usually slow growth, painless, may fell rough or like a bump. Pearly pink surface. With growth can ulcerate & bleed & itch. See derm please. ...Read more

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Whats non-small cell carcinoma?

Whats non-small cell carcinoma?

Non Small cell ca: Is the most common type of lung cancer, another type is small cell ca (which is more aggressive). Both are challenging to diagnose at an early stage. Please consult with your oncologist for prompt diagnosis, and treatment options. Good luck. ...Read more

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Can merkel cell carcinoma be inherited?

Can merkel cell carcinoma be inherited?

Not inherited: Merkel cell carcinoma, a neuroendocrine tumor of the skin, is not inherited. The majority of these tumors in fact seem to be associated with a virus (merkel cell polyomavirus). ...Read more

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What is a small cell neuroendocrine carcinoma?

What is a small cell neuroendocrine carcinoma?

Aggressive tumor: Small cell lung cancer is a neuroendocrine carcinoma that exhibits aggressive behavior, rapid growth, early spread to distant sites, exquisite sensitivity to chemotherapy and radiation, and frequent association with distinct paraneoplastic syndromes, including hypercalcemia Frequently goes to brain for which prophylactic RT given ...Read more

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Non-small cell carcinoma vs small cell carcinoma?

Non-small cell carcinoma vs small cell carcinoma?

Small cell was: Distinguised because there is almost never a role for surgery, and always a role for chemotherapy. Non-small cell prior to 1980 never had chemotherapy. Both are caused by smoking sclc 100%; /nsclc 90-95%. Nsclc just in lung usually treated with surgery. Any + node gets chemo. If mediastinal nodes are positive, standard is chemo/xrt. Get more than 1 opinion before starting treatment if yo have ? ...Read more

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What would the life expectancy for small cell carcinoma be?

What would the life expectancy for small cell carcinoma be?

It depends on the St: Small cell lung cancer can be localized to chest (called Limited disease) or it can be spread outside of the chest and involve other organs like liver/ Bone etc when it is called Extensive disease. So you need to tell us if your lung cancer is Limited disease or Extensive Disease? Then we can give you the relevant information about prognosis. ...Read more

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Is there help for metastatic small cell carcinoma that I can live?

Is there help for metastatic small cell carcinoma that I can live?

Consult Oncologist: We can not answer but suggest you consult a oncologist as the prognosis depends on the extent of disease including metastasis and many other factors.Only they can comment on the prognosis ...Read more

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What is the definition or description of: Non small cell carcinoma?

What is the definition or description of: Non small cell carcinoma?

Lung cancer: It is broad class of lung cancers. You may consult this site for more info: http://www.webmd.com/lung-cancer/non-small-cell-lung-cancer#1 ...Read more

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Will my brother survive merkel cell carcinoma? Nothing seems to be working

Tough disease: This is often a difficult disease to treat. In order to better answer your question please include details about what stage it is, and what treatment he has already had. ...Read more

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Non-small cell carcinoma and small cell carcinoma. What is the difference?

Non-small cell carcinoma and small cell carcinoma.  What is the difference?

Small cell. all else: Small cell cancer of the lung is a specific kind of cancer that has uniform, small cells. Non small cell cancer is the term for all other cancers that are in the lung, like adenocarcinoma, squamous cell cancer, and large cell cancer. These are grouped this way due to treatment approach. Small cell presents as widely disseminated and gets chemo., while non small cell is localized, gets surgery. ...Read more

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Could teenagers have renal cell carcinoma?

Could teenagers have renal cell carcinoma?

Yes: It's not common. If it does appear, it raises suspicion for a hereditary predisposition (von hippel - lindau, others). There are a few pediatric kidney cancers that mimic common renal cell carcinoma clinically but are distinct pathologic entities. ...Read more

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What's the latest on "islet cell transplantation" for type 1 diabetics?

What's the latest on "islet cell transplantation" for type 1 diabetics?

Not so good: We have a long way to go. The edmunton protocol, the latest attempt at transplanting islet cells is not working out as well as we would like for patients with type 1 diabetes.
There are other attempts on the horizon - stay tuned. ...Read more

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Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

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Can you tell me about pancreatectomy with autologous islet cell transplantation?

Can you tell me about pancreatectomy with autologous islet cell transplantation?

Total pancreas out: Most of the islet cells that produce glucagon and insulin are in the body and distal pancreas so that to have them removed requires a total pancreatectomy. Autologous transplants are being performed at the present time by Dr.Horatio Rilo but if not perfomed. hormone replacement required as wll as pancratin for digestion. ...Read more

Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more