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Doctor insights on: Is Zoloft The Most Effective Medication For Anxiety And Depression

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Is Zoloft the most effective medication for anxiety and depression?

One of several: Zoloft is an effective drug for treating anxiety and depression. Other drugs in its class (ssris) are also effective for these conditions. The most effective drug is the one you tolerate which works. ...Read more

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Dr. Pamela Pappas
4,420 doctors shared insights

Depression (Definition)

Include being down or sad most of the time, loss of interest/pleasure in usual activities, unintended increase or decrease in appetite/weight, sleeping more or less than usual, being agitated or lethargic, feeling worthless or inappropriately guilty or self critical, having difficulty concentrating or making decisions, & thinking of death & dying. Suicidal ...Read more


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What can i do if i take Zoloft is good for my depression not good for anxiety Cymbalta good fo anxiety not depression? I tried lots of medication

What can i do if i take Zoloft is good for my depression not good for anxiety Cymbalta good fo anxiety not depression? I tried lots of medication

Both: You can take them both together, providing you tolerate it. They kind of work differently, and unlikely to cause any major drug interactions. ONe is a so called ssri (zoloft) which increases serotonin, and the other SNRI ( cymbalta) which increases norepinephrine. ...Read more

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Zoloft 100mg helped anxiety but not depression, Effexor 150mg helped depression but not anxiety. is there a medication that will help both?

Zoloft 100mg helped anxiety but not depression, Effexor 150mg helped depression but not anxiety. is there a medication that will help both?

Both can help: Both meds can treat anxiety and depression. My suggestion is to work with your prescriber to try a higher dose of either med to see if one can treat both. Although, generally not recommended I have combined these two meds for the reason you stated. I sometimes find doses of Effexor above 150mg cause more anxiety. An alternative idea might be to add buproprion to Zoloft adjusting each. ...Read more

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Zoloft 100mg helped anxiety, Effexor 150mg helped depression. is there a medication that will do both? with minimal sexual side effects?

Zoloft 100mg helped anxiety, Effexor 150mg helped depression. is there a medication that will do both? with minimal sexual side effects?

Mood TX risk/benefit: there are a couple of antidepressants that might help: a new one is Brintellix which has a good side effect profile with little sexual dysfunction reported. Older ones include Remeron and Wellbutrin. Remeron can be added to other treatments. Zoloft and Effexor ought not to be taken together due to a risk of a serotonin syndrome...which is life-threatening! ...Read more

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I was prescribed Zoloft for my anxiety and depression. And. That pill didn't help at all. What other medications can I talk to my dr about taking ins.

I was prescribed Zoloft for my anxiety and depression. And. That pill didn't help at all. What other medications can I talk to my dr about taking ins.

Many choices: If this is your first try at mood maintenance meds, you have many good medicines for a next try: lexapro, celexa, cymbalta. Be sure to give each medicine a decent try - at leat a month. If you have an intolerance, hang in there and give the medicine a full month to "percolate" in your system. Be careful, though, this whole group has a possibility of sexual side effects (decreased libido or climax). ...Read more

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28yo fem w/ depression, anxiety. Zoloft for ~10 yrs, 50mg then 75. Added welbutrin. Zoloft quit helping, tried lexapro. Big weight gain. Rec new drug?

28yo fem w/ depression, anxiety. Zoloft for ~10 yrs, 50mg then 75. Added welbutrin. Zoloft quit helping, tried lexapro. Big weight gain. Rec new drug?

Antidepressants best: Another antidepressant, possibly snri like Effexor may be more helpful at this time. Add ons such as gaba- calm and natural anxiety aids can help. They do cause weight gain usually. Therapy is always an important treatment modality for depression and anxiety, don't think it is not helpful! ...Read more

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Which is a better anti depressant drug to treat panic attacks, anxiety and depression. Lexapro or zoloft?

Both Potentially: Lexapro and zoloft are similar medications and have both been shown to be helpful for panic, anxiety, and depression. There is probably a decreased percentage of side effects with lexapro, so it might be preferable for that reason. However, plenty of people do well with either medicine, and I have had some patients do well with zoloft after not getting benefit with lexapro. ...Read more

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I've started taking Zoloft for my anxiety and depression 5 days ago. Can I have a few drinks just one night every weekend?

I've started taking Zoloft for my anxiety and depression 5 days ago. Can I have a few drinks just one night every weekend?

Don't recommend: Zoloft + alcohol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. See: http://pubs.niaaa.nih.gov/publications/Medicine/medicine.htm I hope this helps. Best wishes. ...Read more

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If Zoloft is helping reduce my pain, does this suggest my pain is caused by my anxiety/depression ?

If Zoloft is helping reduce my pain, does this suggest my pain is caused by my anxiety/depression ?

Not necessarily: Zoloft is an SSRI type of drug. This class of medications, though primarily used & indicated for treating depressive mood disorders & related psychiatric phenomenon, also has analgesic properties. PLEASE-Don't misinterpret what I say by thinking you can use Zoloft like aspirin or hydrocodone...YOU CAN'T but over the long haul these medications can alter pain reception & this is independent of mood ...Read more

Dr. Heidi Fowler
3,036 doctors shared insights

Anxiety (Definition)

Anxiety is a general term for several disorders that cause nervousness, fear, apprehension, and worrying. These disorders affect how we feel and behave, and they can manifest real physical symptoms. Mild anxiety is vague and unsettling, while severe anxiety can be extremely debilitating, having a serious ...Read more


Dr. Donald Jacobson
1,017 doctors shared insights

Sertraline (Definition)

Also called zoloft, is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more