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Doctor insights on: Is Wellbutrin Good For Depression

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Is wellbutrin (bupropion) good for depression and stopping smoking?

Is wellbutrin (bupropion) good for depression and stopping smoking?

Yes 4 some: Some depressed pts & some smokers are helped by wellbutrin (bupropion). ...Read more

Dr. Pamela Pappas
4,598 Doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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Good day, I put on Nuzak and Wellbutrin by my GP about 4 years ago due to depression. I hate being on it and would like wean off. Any advice please?

Good day, I put on Nuzak and Wellbutrin by my GP about 4 years ago due to depression. I hate being on it and would like wean off. Any advice please?

Weaning off: It is important to check with the treating doctor about going off or lowering doses of these medications. If you have been in remission and doing well, it might be possible as long as it is slowly weaned, one by one. Your doctor must guide you and plan it with you. ...Read more

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Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Use alternative: Unfortunately Prozac (while an awesome drug) can interact with quite a few medications. Usually the SSRI + Wellbutrin (bupropion) combo is a great and very commonly used therapeutic option for patients suffering with depression and anxiety. There are plenty of efficacious and safer alternatives. Hope that helps! ...Read more

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Is wellbutrin and effexor (venlafaxine) a good combination to treat GAD, OCD, and depression?

Is wellbutrin and effexor (venlafaxine) a good combination to treat GAD, OCD, and depression?

Everyone is diff.: Not all folks will respond the same. However this combination has been tried in so many people in the best with great results. If the symptoms worsen or noticeable side effects then follow up sooner. However many people get good response on this. ...Read more

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Is lexapro and Wellbutrin (bupropion) a good combination for post partum anxiety and depression?

Is lexapro and Wellbutrin (bupropion) a good combination for post partum anxiety and depression?

Discuss w/ OBGYN, etc: Less is best if you are breastfeeding and if one works it may be better than a mix, but ask your pediatrician and OBGYN and psychiatrist if you have one. Please consider good psychotherapy since it's a big help to make these months easier - new mother support is very important! It might even make drugs less needed. Best wishes! ...Read more

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Is it good to combine Prozac with wellbutrin (bupropion) for treatment of depression?

Is it good to combine Prozac with wellbutrin (bupropion) for treatment of depression?

May be: Wellbutin blocks the uptake of norepinephrine & Dopamine while Prozac (fluoxetine) is a ssris so they effect different neurotransmitters & may work 4 u. ...Read more

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Would wellbutrin and Vyvanse be a good combo for narcolepsy and severe apathy w depression? Pristiq (desvenlafaxine) worked but no longer

Would wellbutrin and Vyvanse be a good combo for narcolepsy and severe apathy w depression? Pristiq (desvenlafaxine) worked but no longer

Perhaps: Have you considered modafanil or xyrem [sodium oxybate]?
Stimulants like vyvanse work, and perhaps stimulating drugs like wellbutrin (bupropion).
These drugs are widely considered treatment of choice for narcolepsy. A neurology consult is in order. ...Read more

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Wellbutrin xl does not seem to be helping like I thought it would for depression, I'm already on Paxil, (paroxetine) what's a good antidepressant I can add to paxi?

Wellbutrin xl does not seem to be helping like I thought it would for depression, I'm already on Paxil, (paroxetine) what's a good antidepressant I can add to paxi?

We're not allowed: To recommend drugs on this forum, but there are drugs that "enhance" the effects of anti-depressants. See your MD for a list, because s/he will know more about what your specific medical picture looks like and can avoid trouble by just picking one or the others. ...Read more

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I have GAD & depression Doc add me wellbutrin (bupropion) 150mg XL for sexual dysfunction It works very good for that but make me strong anxiety do I have to stop?

I have GAD & depression Doc add me wellbutrin (bupropion) 150mg XL for sexual dysfunction It works very good for that but make me strong anxiety do I have to stop?

SSRI/SNRI: Usually we treat anxiety disorders with antidepressant that have Anxiety modulating properties like the SSRI's and the SNRI's as well as the old generation of meds. Wellbutrin (bupropion) is not one of them. However we do combine Wellbutrin (bupropion) with SSRI's quite often to address depression and anxiety. Good luck and feel better ...Read more

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I take wellbutrin (bupropion) for depression. My gastro prescribed hyoscymine for biliary. I read it is a serotonin antagonist. It that good or bad for my m.?

No interaction: Wellbutrin (bupropion) doesn't have a direct effect on serotonin (unlike other antidepressants) and therefore Hyoscyamine should be fine. Not sure what you meant by "it that good or bad for my m.? " but hope this helps. ...Read more

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Off zoloft and now given Wellbutrin. I don't know if im depressed or anxious or both. My doctor keeps trying different meds. Good med for saddness?

Off zoloft and now given Wellbutrin. I don't know if im depressed or anxious or both. My doctor keeps trying different meds. Good med for saddness?

Sadness: Sadness is very different from a major depression. Sadness is a human feeling that all of us experience at sometime in our lives., Antidepressants do not resolve sadness- seeing a mental health professional can help. In my practice I feel it is very important to carefully evaluate the patient. Antidepressants have significant side effects. See a psychiatrist and get a careful evaluation

...Read more

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Is wellbutrin (bupropion) for ADHD and depression?

Is wellbutrin (bupropion) for ADHD and depression?

Wellbutrin (bupropion) is used: To treat depression. It is excellent for atypical depression. I have seen it used for adhd - but usually when more typical adhd medication were not an option. (off label). ...Read more

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How effective is Wellbutrin (bupropion) for treating depression?

Wellbutrin (bupropion): Works for some, especially for depression with low energy. ...Read more

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Does wellbutrin (bupropion) help with depression?

Yes: It is best to speak specifically with you physician about your particular details. However, in general, wellbutrin (bupropion) can help treat a major depressive episode. Wellbutrin (bupropion) particularly helps when symptoms of low energy and poor concentration are present. The sexual side risk of wellbutrin (bupropion) are lower than other antidepressants. ...Read more

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How long can a person be treated for depression with wellbutrin (bupropion)?

How long can a person be treated for depression with wellbutrin (bupropion)?

Wellbutrin (bupropion): For first episode of depression, usually 6 months to a year. If recurrent, it takes longer. ...Read more

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I'm using Wellbutrin (bupropion) to treat depression, how do I tell if it's working for me?

Feel better but. .: Know that it make time for a medication to really "kick in" for you. As your body's neurochemistry has to adjust and/or the dose needs to be right for you. This can takes weeks if not months. But if it's going to work for you, you should feel some improvement in your moods, or energy levels, or desire to be active, or ability to concentrate. ...Read more

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Vyvanse and wellbutrin (bupropion) for add and depression, is that okay?

Vyvanse and wellbutrin (bupropion) for add and depression, is that okay?

Yes: Those two meds can be used together to treat those disorders. Unfortunately they will not overlap and provide benefit for both disorders. There is always the potential for some type of drug interaction or to just not feel well with both meds on board so it is importannt to have close follow up with the prescribing provider ...Read more

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Hat should I do if Wellbutrin (bupropion) is worsening my depression?

Hat should I do if Wellbutrin (bupropion) is worsening my depression?

Is it worsening it: Or just not ameliorating the symptoms? What is the dose, and for how long? What are the psychological events in your life? Is there a history of depression in the family, or during winter? Lots of questions--all should be asked by a psychologist or psychiatrist. Some meds actually cause the symptoms they purport to treat. You need an MD to assess that part. ...Read more

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How does wellbutrin (bupropion) (and similar meds) help with depression and anxiety?

Dep, usu not anxiety: Wellbutrin (bupropion) helps 2/3 to 3/4 of patients with clinical depression feel better, about the same as other antidepressants. It is not an anti-anxiety med, and won't help anxiety directly. However, sometimes anxiety is a symptom of depression. In this case, if the depression is treated the anxiety may go away as well. ...Read more

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Can wellbutrin (bupropion) and lithium improve anxiety, depression, and overal mood?

Can wellbutrin (bupropion) and lithium improve anxiety, depression, and overal mood?

Bipolar disorder: Bipolar disorder is often helped by lithium, which is a mood-stabilizing medication. Sometimes depression is severe enough despite this that an antidepressant like wellbutrin (bupropion) is added -- but not without the mood stabilizer. If prescribed by your psychiatrist and you are followed regularly, the combination may help your mood, wellbutrin (bupropion) is not an anti-anxiety medication, though. ...Read more

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I am currently on Wellbutrin (bupropion). Can I also take the herb Rhoziva to help with depression and managing stress?

Not a Good Idea: There is no scientific methodology to evaluate possible interactions between herbal supplements and medications that might be prescribed by a physician. As a result, information is based on animal studies, case reports, and historical contraindications. Rhozia, a herbal
supplement from Siberia increases dopamine/serotonin & might interfere with wellbutrin (bupropion). Avoid it. ...Read more

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Can one take a combo of Cymbalta and Wellbutrin? Cymbalta works well for my depression but Wellbutrin erased my alcohol cravings.

Cymbalta Wellbutrin: Cymbalta and Wellbutrin can be safely combined. The Cymbalta levels may be increased, but I have not seen this become a problem. The addition of Wellbutrin to SSRI antidepressants is a well studied augmenting method. ...Read more

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Can I take Wellbutrin (bupropion) XL 300 Mg for depression while pregnant? I came off of my meds after thinking that I could possibly be pregnant. What to do?

Consult your doctor: The vast majority of medications (including non-prescription and homeopathic, herbs, alternatives, etc) have the potential for causing birth defects. Therefore, first determine your pregnancy status then, consult your physician for whether you should be taking Wellbutrin (bupropion) if you are pregnant. It is rated Category C for pregnant women which means it's best avoided unless benefits outweigh risks. ...Read more

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Does wellbutrin (bupropion) work very well for ADHD and depression?

Does wellbutrin (bupropion) work very well for ADHD and depression?

Wellbutrin (bupropion) is: Excellent for atypical depression/ seasonal affective disorder. Would not use it first line for adhd. However, it can be used off-label for that purpose. ...Read more

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I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

I am being prescribed Lexapro, wellbutrin and elavil for depression and anxiety. Is this combo safe?

Drug Interactions: Elavil (amitriptyline) + Wellbutrin (bupropion) ^ es seizure risk. Escitalopram +amitriptyline ^'es risk of serotonin syndrome. Wellbutrin + Lexapro ^es seizure risk. I am assuming that the Elavil is added in for insomnia or pain control and not for depression/ anxiety. This does not mean that these drugs can't be used together but there are possible drug interactions. D/W your physician. ...Read more

Dr. Alan Ali
792 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more