Top
40
Doctor insights on: Is Uninodular Goiter Cancer

Share
1

1
Is multinodular goiter preventable?

Is  multinodular goiter preventable?

Unknown.: Unfortunately, the reasons for nodule development in the thyroid gland are not well understood. ...Read more

See 1 more doctor answer
Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
Is a heterogeneous thyroid nodule cancerous?

Is a heterogeneous thyroid nodule cancerous?

Possibly: Each thyroid nodule has an approx. 5% chance of malignancy, thus a heterogenous could be cancerous. Looking at it the other way, a heterogenous nodule has a 95% chance of not being cancerous. ...Read more

See 3 more doctor answers
3

3
What is anaplastic thyroid cancer?

What is anaplastic thyroid cancer?

An aggressive tumor: This is an aggressive form of thyroid cancer that can come back rapidly and is general treated with a combination of surgery, radiation therapy, and chemotherapy. ...Read more

See 3 more doctor answers
4

4
Is toxic goiter curable?

Yes: There are many types of thyrotoxicosis. You should see a thyroidologist. ...Read more

5

5
What is a multinodular goiter?

Large thyroid lumps: A 'goiter' refers to an enlarged thyroid gland. A multi-nodular goiter is usually diagnosed on an ultrasound scan when many lumps or 'nodules' are seen. Typically these are benign. 3 things to consider for nodular goiter: 1) big enough overall to cause problems with swallowing, voice, or breathing? 2) do nodules over-produce thyroid hormone? 3) are any of the larger or irregular nodules cancer? ...Read more

6

6
What is a nodular goiter?

Thyroid with masses: Goiter usually means an enlarged thyroid gland, but can also refer a normal-sized gland with nodules or masses within it. Thyroid nodules are areas within the gland that stick out from the gland and can be felt when pressing on the neck, or may be areas that appear different from the normal gland on imaging tests like ultrasound or cat scans. ...Read more

See 1 more doctor answer
7

7
What is a non toxic uninodular goiter?

A nodule: Hi. A non-toxic uninodular goiter means you have a nodule in the thyroid that is NOT autonomously over-producing thyroid hormone. There is a risk the nodule is a thyroid cancer, so your doctor will probably send you to an endocrinologist to get a fine needle aspiration biopsy. If the nodule is benign, you leave it alone; if it's cancer, you head down that path (most are benign). Good luck. ...Read more

8

8
Is goiter hereditary?

Goiter: Some goiters are present in several family members and some are not. If you are concerned about getting it yourself because others in the family have been diagnosed with this in the past. Have your PCP check your thyroid (physical exam) and order appropriate lab studies and if it is OK don't worry but get the same labs done annually. ...Read more

9

9
Can a nontoxic uninodular goiter become cancerous?

Can a nontoxic uninodular goiter become cancerous?

May need biopsy: A solitary nodule in a goiter, that is "cold" on scan, needs to be biopsied by someone who is good at this. Although the likelihood of cancer is low, maybe 10%, but it needs to be checked out. ...Read more

11

11
What is papillary thyroid carcinoma?

What is papillary thyroid carcinoma?

PTC: Hi. Papillary thyroid cancer (PTC) is the most common type of thyroid cancer, and generally also carries the best prognosis. General sequence is detect a nodule, do needle biopsy (find cancer), do ultrasound of neck looking for lymph nodes, have thyroid and suspicious nodes surgically removed, get treated with radioactive iodine. TSH suppression lifelong in most cases. Follow serum thyroglobulin. ...Read more

12

12
What is an adenomatous goiter?

What is an adenomatous goiter?

Adenomatous Goiter: It is a goiter due to growth of multiple encapsulated adenomas or multiple non encapsulated colloid nodules within its substance. ...Read more

13

13
Can huge hypervascular thyroid nodule be goiter?

Yes: By definition, any enlargement of the thyroid gland is a goiter. So if the nodule is causing the thyroid to be enlarged, there is a goiter. The question is, what is the cause of the nodule? Sounds like a biopsy is in your future. ...Read more

14

14
Is thyroid cancer genetic?

Is thyroid cancer genetic?

Perhaps: Known genetic mutations are seen in thyroid cancers: braf in papillary; kras in follicular; ret gene (usually point mutation) involving 10q11.2 in medullary carcinoma; p53 in undifferentiated carcinoma. However, "inherited" types of thyroid carcinoma are much less common - although medullary carcinoma is the most common type. ...Read more

See 2 more doctor answers
16

16
What is a exophytic thyroid nodule?

thyroid: Exophytic refers to a nodule that sticks out of the normal thyroid boundary/outline. ...Read more

See 1 more doctor answer
18

18
Is hypoechoic cancer?

Is hypoechoic cancer?

Not necessarily: This is a description of ultrasound characteristics of a finding - it doesn't bounce back sound waves in relation to surrounding structures. More often, benign findings or cysts are hypoechoic. Additional scans may help confirm. ...Read more

See 2 more doctor answers
19

19
What is thyroid cancer?

What is thyroid cancer?

Often curable cancer: The thyroid gland is in the lower neck and makes essential hormones. Cancers of the thyroid gland are of multiple types; the most common is of the pappliary subtype. Often surgery is the first step of treatment followed by treatment with trace amounts of radioactive iodine which destroys any remaining cancer. In most cases survival and cure rates are very good. ...Read more

See 1 more doctor answer
21

21
Can a nontoxic uninodular goiter become cancerous?

May need biopsy: A solitary nodule in a goiter, that is "cold" on scan, needs to be biopsied by someone who is good at this. Although the likelihood of cancer is low, maybe 10%, but it needs to be checked out. ...Read more

22

22
What exactly does nontoxic uninodular goiter mean/?

What exactly does nontoxic uninodular goiter mean/?

Goiter: Goiter is simple enlargement of the thyroid gland. Most often, it's due to insufficient dietary iodine or familial inheritance. Non-toxic means that you are not producing an abnormal amount of thyroid hormone. Uninodular would specifically mean that you have a single nodule within the thyroid. Usually a solitary nodule should be evaluated with needle biopsy or followed closely with ultrasound. ...Read more

23

23
What is a non toxic uninodular goiter?

A nodule: Hi. A non-toxic uninodular goiter means you have a nodule in the thyroid that is NOT autonomously over-producing thyroid hormone. There is a risk the nodule is a thyroid cancer, so your doctor will probably send you to an endocrinologist to get a fine needle aspiration biopsy. If the nodule is benign, you leave it alone; if it's cancer, you head down that path (most are benign). Good luck. ...Read more

24

24
I just got results from a thyroid uptake scan it says they found a toxic uninodular goiter and unspecified goiter I also have itp is there a connection and what exactly is a toxic uninodular goiter also my thyroid is enlarge

I just got results from a thyroid uptake scan  it says they found a toxic uninodular goiter and unspecified goiter I also have itp is there a connection and what exactly is a toxic uninodular goiter also my thyroid is enlarge

Get thyroid labs: You most likely already have your thyroid levels checked. If not, you need to get thyroid labs drawn. From the uptake and scan above, your TSH should be low, which indicates hyperthyroidism. The treatment is 1)antithyroid drug, 2)i-131 ablation, 3)surgery. With itp, maybe hold off on surgery for now. Please discuss all of this with your doctor. Good luck. ...Read more

See 2 more doctor answers
25

25
Help please! could calcified thyroid goiters can become cancer?

Help please! could calcified thyroid goiters can become cancer?

Usually not: The rate of cancer arising in these idiopathic goiters is surprisingly low, though the cancers themselves are hard to find. If there is a dominant mass in the enlarged gland, it should be checked. ...Read more

26

26
My doctor wants to watch the isthmus nodule that came bk atypical benign foll cells...Its 2.7 with goiter..I want all out not wait for cancer...Help?

Find another doctor: You can always look and find another doctor/specialist who can get it removed. When in doubt, seek a second medical opinion! ...Read more

27

27
I have a 2cm complex cyctic multinodule goiter on my right thyroid and a 4 CM one on my left side no calcifications what are the chances its cancer ?

Cancer risk: Each nodule has a 5% chance of cancer. Your nodules are large and should be evaluated (biopsy). Keep in mind that the bigger the nodule, the higher the risk that the biopsy will come back negative (benign) although the cancer is still there (false negative). You are very young and if the nodules are causing some compressive symptoms now, surgery might be a good option for you. ...Read more

28

28
I have hyperthyroid and have a goiter on my neck. Can it become cancer?

I have hyperthyroid and have a goiter on my neck. Can it become cancer?

Not likely: There are several possible explanations for hyperthyroidism + goiter. At age 35, the most common cause is graves' disease, not a cancerous condition. Sometimes hyper is caused by multiple thyroid nodules. In that case, we do a iodine thyroid scan to identify nodules causing the hyper (hot nodules) and nodules not causing it (cold). Cold nodules can be cancerous, but not very often. ...Read more

29

29
Have goiter + 6 micronodules, not suspicious on 2 US. TSH 2.2 FT3/4 OK. Anti Tpo 1309 Anti TG 117. Goiter fluctuates size. Is it likely to be cancer?

Have goiter + 6 micronodules, not suspicious on 2 US. TSH 2.2 FT3/4 OK. Anti Tpo 1309 Anti TG 117. Goiter fluctuates size. Is it likely to be cancer?

Not very likely: B"sd sounds fairly typical for Hashimoto's thyroiditis, which commonly causes coarse echoes on thyroid US images. Also, nodules are often seen, many of which are pseudonodules due to thyroid inflammation only, and tend to come and go over time. Dr will keep up with serial US to watch for growing or otherwise suspicous nodules that might suggest cancer with need for needle biopsy or surgery ...Read more

30

30
Have goiter with 6 micronodules. US say nodules not suspicious. A-TPO 1,309 A-TG 117. TSH, FT3/4 normal. Goiter size fluctuates. Could this be cancer?

Not likely: Multinodular lesions/goiter are not uncommon. It would be prudent to follow your doctor's advise for continuing care to watch out for any changes. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

31

31
Would there be a reason to remove your thyroid gland without you having cancer or a goiter?

Yes: Thyroid cancers especially in adults must be resected. Younger patients do better even if tumor has spread to nodes. Goiters getting large can obstruct the breathing passages and may need surgery, but a small solitary adenoma of the thyroid that is benign but cold in terms of isotope uptake should be removed because of the high conversion rate to malignancy over time. ...Read more

33

33
Is thyroiditis (based on u/s that showed borderline thyroid enlargement /goiter) related to thyroid cancer? If no nodes were seen? Have globus symptom

Is thyroiditis (based on u/s that showed borderline thyroid enlargement /goiter) related to thyroid cancer? If no nodes were seen? Have globus symptom

Globus: You started with a globus sensation which may be due to an anxiety disorder. You had a thyroid U/S done which sounds to be NORMAL. thyroiditis is not diagnosed on ultrasound, its based on hormone levels. You have no goiter or nodules. You have a normal exam. You need to address the globus. You can get an ENT exam with laryngopharyngoscopy and talk to your doctor about treating anxiety or OCD. ...Read more

34

34
Multinodular goiter dx. Us biopsy of thyroid- benign. What's the treatment for goiter? history of cancer- can't i just get it removed prophylacticly?

Multinodular goiter dx. Us biopsy of thyroid- benign. What's the treatment for goiter? history of cancer- can't i just get it removed prophylacticly?

Why?: Unless it represents a danger like cancer, or is a severe physical or cosmetic problem, why remove an organ "prophylactically"/ if that were true, why not also "prophylactically" remove your nose, breasts, external ears, toes, one kidney......And all the other parts of your body you don't really need that could potentially cause trouble in the future? ...Read more

See 1 more doctor answer
37

37
With history of graves disease, and now TSH 7 and multinodular goiter, likelyhood of cancer?

With history of graves disease, and now TSH 7 and multinodular goiter, likelyhood of cancer?

Increased likelihood: Yes, likelihood of thyroid CA is increased with chronic thyroid disease like yours. It does not mean though that you already have or definitively will have CA, but you MAY develop it. You must be monitored to have a chance to catch CA early. At this time the only advise I give is to be consistent with your treatments and follow ups as it is recommended by your treating MD. ...Read more

See 1 more doctor answer
38

38
I had a partial thyroidectomy and the radioactive iodine treatment for the other side due to goiter-nodule with small cancer. Synthroid (thyroxine) reduced-why?

I had a partial thyroidectomy and the radioactive iodine treatment for the other side due to goiter-nodule with small cancer. Synthroid (thyroxine) reduced-why?

For RAI to Work: The overall treatment is a little confusing as cancer is usually surgically removed, but there are a few reasons to lower your Synthroid (thyroxine). It may be held for a while so your left over thyroid tries to work and will suck up the RAI. The other reason is when the thyroid cells die they will release thyroid hormone. This could temp make you hyperthyroid. Eventually your dose will be adjusted again. ...Read more

See 1 more doctor answer
39

39
Can a very slight increase in calcium levels in blood work indicate cancer? I do have athyroid goiter with normal TSH & a mass in neck of my r femur.

Can a very slight increase in calcium levels in blood work indicate cancer?  I do have athyroid goiter with normal TSH & a mass in neck of my r femur.

Seek other cause: The slightly elevated calcium will be worth repeating, but it will not make or break the cancer workup. It'll be your physician's decision whether or not to biopsy the mass in the femur, simply wait, or do more imaging. I trust your "amyloid goiter" is not really a medullary carcinoma with coexisting parathyroid disease (multiple endocrine neoplasia ii). ...Read more

Dr. Steve Martinez
316 doctors shared insights

Thyroid Enlargement (Definition)

Thyroid enlargement refers to a thyroid gland that is larger than normal. The thyroid gland is located in the front of the neck, below the Adam's apple, and may become enlarged due to hyper or hypo-thyroidism. An enlarged thyroid is also ...Read more