Doctor insights on:
Is Trileptal Better Than Lyrica And Neurontin For Face Pain
Cost and absorption: Gabapentin (neurontin) and Pregabalin (lyrica) are structurally similar and have similar effects pharmacologically. Pregabalin is absorbed better and is more potent in some studies, however it is also quite a bit more expensive since it is not available as a generic. ...Read more
Basically price: Gabapentin is older and available generically, so much cheaper. Lyrica (pregabalin) is newer dosages are different and somewhat less frequent than gabapentin. Lyrica (pregabalin)- because it is newer has more indications ( labelled uses- ie postherpetic neuralgia and fibromyalgia) but Gabapentin will work just as well. Gabapentin(neurontin) was originally marketed for seizure disorders but more commonly used for neuralgi. ...Read more
Mechanisms of action: Meds that act on calcium channels = Gabapentin and lyrica; likely no new meds with that same mechanism of action for a while. But, existing meds for neuropathy w/ different moa include Cymbalta & venlafaxine (snris), Amitriptyline and other heterocyclic antidepressants, tizanidine (alpha2 agonist), vimpat (lacosamide) (anticonvulsant), Alpha lipoic acid, and vitamin B12 + b6 + folate supplements. Take care! ...Read more
See below: It was designed as a more potent successor to gabapentin. Recent studies have shown that Pregabalin is effective at treating chronic pain in disorders such as fibromyalgia and spinal cord injury. In june 2007, Pregabalin became the first medication approved by the U.S. Food and drug administration specifically for the treatment of fibromyalgia. Neurontin is not approved for this use (but is used. ...Read moreSee 1 more doctor answer
Is it ok to take Lyrica (pregabalin) and Neurontin? I use Neurontin to help me sleep at night. Won't take together just same day
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